Imprinted genes in humans

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Imprinted genes as potential genetic and epigenetic toxicologic ...Imprinted genes are necessary for normal mammalian development. ... Dissociation of IGF2 and H19 imprinting in human brain. Brain Res. tw | twGenomic Imprinting: Implications for Human Disease - NCBI1999年1月6日 · Consequently, abnormal expression of these genes results in numerous human genetic disorders including carcinogenesis. This paper reviews ... tw | twCatalogue of Imprinted Genes and Parent-of-Origin Effects in ...Additionally, we now recognize several phenotypes in humans, mice and other animals which show a pattern of inheritance consistent with the involvement of ... | Genome-wide identification of new imprinted genes2010年6月29日 · Nevertheless, the number of identified imprinted genes is unlikely to be complete as the precise extent of imprinting in the mouse or human ...Genomic Imprinting: Implications for Human Disease - The American ...Genomic imprinting differs from classical genetics in the sense that the parental complement of imprinted genes are not equivalent with respect to their ...Genome-wide prediction of imprinted murine genesImprinted genes are epigenetically modified genes whose expression is ... Subset of mouse chromosome 7f5 that is homologous to the imprinted human BWS ...A model system to study genomic imprinting of human genes | PNASAbstract. Somatic-cell hybrids have been shown to maintain the correct epigenetic chromatin states to study developmental globin gene expression as well as ... tw | twMonoallelic expression and methylation of imprinted genes in ...2002年8月6日 · This model should allow experimental manipulation of epigenetic modifications of cultured EG cells that may not be possible in human stem cell ...Mechanisms of Genomic Imprinting - Cell PressImprinted genes are often associated with human diseases, including disorders affecting cell growth, development, and behavior.Evaluation of Allelic Expression of Imprinted Genes in Adult Human ...2010年10月21日 · Imprinted gene expression status in the healthy adult human has for obvious reasons been difficult to characterise. Peripheral blood leukocytes ...