Tibolone mechanism of action

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Postmenopausal Tibolone Therapy: Biologic Principles and Applied ...2007年1月3日 · Tibolone, an analogue of the progestin, norethynodrel, is a drug with tissue- specific effects on ... Tibolone: a steroid with a tissue-specific mode of action. ... Rubin GL, Harrold AJ, Mills JA, et al. ... Twitter; Share on Google Plus ...Tissue-selectivity: the mechanism of action of tibolone - PubMedTibolone appears to regulate estrogenic activity in the various tissues by influencing the availability of estrogenic compounds for the estradiol receptor in a tissue-selective manner.Tibolone as Hormonal Therapy and Neuroprotective Agent: Trends ...2020年6月4日 · The aim of this review is to discuss the mechanism of action of TIB, its systemic effects, and the risk associated with its use, especially ...Cardiovascular Effects of Tibolone: A Selective Tissue Estrogenic ...2007年7月3日 · Tibolone possesses a tissue‐selective mechanism of action that differs from that of estrogen and/or progestogen. Unlike these compounds ...Endometrial Effects of Tibolone | The Journal of Clinical ...Background and Objectives: The Tibolone Histology of the Endometrium and Breast ... The mechanism of action of tibolone is supportive for the observation that ...Tibolone (Livial, Liviella, CAS Number: 5630-53-5) | Cayman ...Three major metabolites of tibolone are responsible for its tissue selective mechanism of action. Conversion into 3α- and 3β-hydroxy-tibolone results in estrogenic ...Tibolone - WikipediaTibolone, sold under the brand name Livial among others, is a medication which is used in ... of postmenopausal women". Taiwan J Obstet Gynecol. ... "Tibolone: a steroid with a tissue-specific mode of action". J. Steroid Biochem. Mol. Biol.Effects of Tibolone on the Breast of Postmenopausal Women ...Taiwan J Obstet Gynecol, 44 (2005), pp. 327-331 ... ML Stefanick, GL Anderson, KL Margolis, et al. ... Tissue-selectivity: the mechanism of action of tibolone.Tibolone | DrugBank Online2015年5月14日 · Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist ... Mechanism of action.(PDF) Effects of Tibolone on the Breast of Postmenopausal Women2021年2月17日 · Taiwan J Obstet Gynecol •June 2007 •Vol 46 •No 2 121 ... has provided a clearer insight into the mechanism and. action of tibolone, which is significantly different from. those of ... Stefanick ML, Anderson GL, Margolis KL, et al.


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