林赫 - 中興大學生命科學系

林赫[ 教授 ] ... 2017: 高筱涵,林薰妤,莊家驊 2018: 張婷捷, 張智瑩 2019: 方晧, 林奇翰, 陳巧倫, 張景明 大學生- 李冠勳(國科會計畫2006-中興生科所) 林赫[教授] 內分泌與腫瘤實驗室 辦公室電話： (04)22840416#310 實驗室電話： (04)22840416#311 傳  &nbsp   真 ： (04)22874740 實驗室位置： 生命科學大樓308室 最高學歷 ： 國立陽明大學博士 專長領域 ： 生理學、細胞生物學、腫瘤生物學、生理藥理學、內分泌學、神經生物學  電子信箱 ： [email protected] 實驗室網站： https://orcid.org/0000-0001-7849-9137    學歷 經歷 研究方向 開設課程 研究室人員 學術著作 年份 標題 2018 國立中興大學「特聘教授」 2017 國立中興大學「特優導師」 2016 指導本系學生郝貞明參與科技部大專學生專題研究計畫榮獲105年度"研究創作獎" 2015 國立中興大學「優秀年輕學者獎助計畫-懷璧獎」 2013 國立中興大學傑出青年教師 2012 指導博士班學生獲得第二十屆細胞及分子生物新知研討會優秀論文獎(許馥甯) 2011 國立中興大學傑出青年教師獎 2011 指導博士班學生獲得第七屆亞太平洋生理學會大會優秀論文獎(許馥甯)及論文佳作獎(黃寶萱) 2011 指導博士班學生獲得美國細胞生物學會年會之旅行獎(許馥甯) 2010 獲邀參加"第三屆台法前鋒科學論壇國際成員養成會議" 2010 獲98年度國立中興大學建教合作計畫之"成長之星" 2010 榮獲99年度國立中興大學產學績優獎 2009 台中榮民總醫院與十大院校合作計畫優良論文 2009 國立中興大學傑出青年教師獎 2008 指導台中一中學生陳其寬獲得第七屆旺宏科學獎金牌 2008 指導本系學生楊旻修參與國科會大專學生專題研究計畫榮獲96年度"研究創作獎" 2007 國科會96年度傑出學者養成計畫 2007 台中榮民總醫院與八大院校合作計畫發表第一名 2006 指導學生獲得2006年(第21屆)生物醫學聯合年會「優秀壁報獎」(學生:陳疇丞) 2004 第12屆細胞及分子生物新知研討會「優秀壁報獎」   畢業學校 主修學門系所 學位 時期 國立陽明大學 生理學研究所 博士 1995~2000 私立東海大學 生物學系 學士 1991~1995   服務機關 服務部門 職稱 時期 國立中興大學 生命科學系 系主任 2019.02迄今 國立中興大學 生命科學系 副系主任 2017.08迄今 國立中興大學 研發處學術發展組 組長 2014.8-2018.7 科技部 生命科學司 專題研究計畫-複審委員 2015~ 國立中興大學 生命科學系 教授 2013.08迄今 ChineseJournalofPhysiology(SCI) EditorialOffice AssociateEditor(副主編) 2013迄今 Pharmacologia 編輯部 編輯 2014/1迄今 台灣內分泌及代謝學會 理事會 理事 2014/5迄今 中國醫藥大學附設醫院 醫學研究部 顧問 2013/8迄今 AmericanJournalofCancerReview 編輯部 編輯 2013/7迄今 亞洲大學 生物科技系 合聘教授 2013/8迄今 Evidence-basedComplementaryandAlternativeMedicine(SCI) 編輯部 編輯 2014/12迄今 中國生理學會 理事會 理事 2014.5迄今 美國德州大學西南醫學中心 泌尿外科 訪問教授 2012.02至2013.01 AdaptiveMedicine期刊 編輯部 副主編 2011.01迄今 台灣調適科學會 理事會 理事 2007~2009 國立中興大學 生命科學系 副教授 2009.02~2014.07 國立中興大學 生物科技發展中心研究發展組 組長 2014.2~2014.7 國立中興大學 生命科學系 助理教授 2004.10~2009.01   研究興趣1各種腫瘤之細胞內訊息傳遞及藥物作用(包括攝護腺癌,乳癌,肺癌,子宮頸癌,膀胱癌,甲狀腺癌等)2內分泌之細胞內訊息傳遞3探討神經分化之分子機制(包括神經退化性疾病)研究主題1癌症的致癌機轉及藥物反應2雄性激素生物合成機轉及受到藥物的影響目前研究計畫1.科技部研究計畫(2017-2020):CDK5與有絲分裂的關係探討2.農委會研究計畫(2016-2017):攝護腺肥大的藥物開發3.科技部龍門計畫(2014-2016):研發可治療具抗性之攝護腺癌的新穎生物源奈米藥劑並探討其專一機制4.國科會專題研究計畫(2015~2016):探討Cdk5蛋白激酶經由調控細胞週期抑制蛋白p21表現而影響乳癌細胞進展之生理機制5.榮總中興合作計畫(2016):探討Cdk5是否可藉由調控HIF-1α而影響癌細胞之VEGF的表現並刺激血管新生6.大專學生暑期研究計畫(2015~2016):探討神經生長因子於攝護腺癌LNCaP細胞株中是否可透過刺激Erk-Egr-1-p35蛋白途徑而活化Cdk5激酶並促進下游雄性激素受體活性及癌細胞生長   現任人員:碩士級研究助理-黎喻暄博士班-彭裕婷,周柔君,高暐翔,MuhammetOner碩士班二年級:廖婉伶,游婉媜,謝丞恩,ShazzadPrince一年級:鄭語喬,鄭邦廷,CelikAyse大學部-劉芳伶,劉冠緯,鄭羽辰,欒玖霖,侯昀君離職人員:博士後研究員-許馥甯(Scientist,BionovaScientificCo,USA)林麗瓊(PostdoctoralFellow,UniversityofGlascow,UK)張智翔(正瀚生技博士後研究員)林君榕(PostdoctoralFellow,UniveristyofTexasSouthwesternMedicalCenter,USA)碩士級研究助理-黃威寰,江明憬,王若馨畢業博士-許馥甯(2011-TexasA&M博士後研究員)蕭宏柏(2011-國家衛生研究院博士後研究員)陳靜嫻(2011-UCDavis助理教授)張仲達(2012-亞東醫院急診部醫師)王心怡(台中榮民總醫院核子醫學科醫師)林筱筠(美國中國醫藥大學博士後研究)林育慶(2015-彰濱秀傳紀念醫院泌尿外科醫師)李岳聰(彰濱秀傳紀念醫院副院長)于家珩(童綜合醫院教學部主任)賴威仲(2016-成大博士後研究員)黃寶萱(2016-衛福部食藥署)張瓊方(2016)畢業碩士-2006:古建得,曾群富,郭宏碩,陳疇丞2007:許馥甯,邱治源,吳承修2008:林俐伶,李冠勳,劉美芳2009:黃威寰,張瓊方,游舜期2010:江明憬,王麗娟2011:洪慶宗,彭裕婷,陳姿吟,林耿志2012:董佩綾,朱敏嘉,連傳岳,黃振權2013:白家明,周敬唐,李培齊2014:邱德桓2015:王若馨,高暐翔,王俊智2016:王建甯,王韻琪2017:高筱涵,林薰妤,莊家驊2018:張婷捷,張智瑩2019:方晧,林奇翰,陳巧倫,張景明大學生-李冠勳(國科會計畫2006-中興生科所)江明憬(國科會計畫2007-中興生科所)楊旻修(國科會計畫創作獎2008-陽明生化所)劉靜宜(國科會計畫2008-成大生理所)黃寶萱(國科會計畫2009-中興生科所)白竹君(2009)曾百功(國科會計畫2011-中興生科所)賴怡君(2015)宋時瑜(2015-陽明藥理所)陳家璋(2015-陽明生藥所)陳一誠(2015-成大生理所)郝貞明(科技部計畫創作獎2016-台大解剖所)馮興凱(2017-陽明大學微免所)陳森強(台大免疫所)張晏慈(台大生化所)張修維(成大生化所)劉念慈(台大生化所)   A.期刊論文  1.LinLC,GaoAC,Lai,CH*,HsiehJT*,andLinH*2017/01Inductionofneuroendocrinedifferentiationincastrationresistantprostatecancercellsbyadipocytedifferentiation-relatedprotein(ADRP)deliveredbyexosomes.,CancerLetters.vol.391,no.74-82.(SCI) 2.ChenYA,LienHM,KaoMC,LoUG,LinLC,LinCJ,ChangSJ,ChenCC,HsiehJT*,LinH*,TangCH*,andLaiCH*2017/01SensitizationofradioresistantprostatecancercellsbyresveratrolisolatedfromArachishypogaeastems.,PLoSOne.vol.12,pp.e0169204.(SCI) 3.HuangPH,ChenMC,PengYT,KaoWH,ChangCH,WangYC,LaiCH,HsiehJT,WangJH,LeeYT,LinE,YueCH,WangHY,YouSC,LinH*2016/12Cdk5directlytargetsnuclearp21CIP1andpromotescancercellgrowth,CancerResearch.vol.76,pp.6888-6900.(SCI) 4.LaiCK,ChenYA,LinCJ,LinHJ,KaoMC,HuangMZ,LinYH,Chiang-NiC,ChenCJ,Lo2016/02MolecularmechanismsandpotentialclinicalapplicationsofCampylobacterjejunicytolethaldistendingtoxin,FrontiersinCellularandInfectionMicrobiology.vol.6,no.9.(SCI) 5.HsiaoHB,HsiehCC,WuJB,LinH,andLinWC*2016/02Kinsenosideinhibitstheinflammatorymediatorreleaseinatype-IIcollageninducedarthritismousemodelbyregulatingtheTcellsresponse,BMCComplementaryandAlternativeMedicine.vol.16,no.80.(SCI) 6.HuangPH,WangHY,HuangCC,LeeYT,YueCH,ChenMC*,LinH*2016SuppressionofbreastcancercellgrowthbyHer2-reducedARserine81phosphorylation,ChineseJournalofPhysiology.(SCI) 7.LinCJ,LaiCK,KaoMC,WuLT,LoUG,LinLC,ChenYA,LinH*,HsiehJT*,LaiCH*,Lin2015/06Impactofcholesterolondiseaseprogression,Biomedicine.vol.5,no.7.(SCI) 8.YueCH,HuangCY,TsaiJH,HsuCW,HsiehYH*,LinH*,LiuJY*2015/05MZF-1/Elk-1complexbindstoproteinkinaseCαpromoterandisinvolvedinhepatocellularcarcinoma,PLoSOne.vol.10,no.5.(SCI) 9.LinHY,HuangBR,YehWL,LeeCH,HuangSS,LaiCH,LinH,andLuDY2014/02Antineuroinflammatoryeffectsoflycopeneviaactivationofadenosinemonophosphate-activatedproteinkinase-α1/hemeoxygenase-1pathways,NeurobiologyofAging.vol.35,no.191-202.(SCI) 10.ChenMC,HsuSL,LinH*,andYangTY*2014Retinoicacidandcancertreatment,Biomedicine.vol.4,no.4,pp.22.(SCI) 11.ShenSC,ShenCI,LinH,ChenCJ,ChangCY,ChenSM,LeeHC,LaiPS,andSuHL*2014Susceptibilityofhumanembryonicstemcell-derivedneuralcellstoJapaneseencephalitis,PLoSOne.vol.9,no.12.(SCI) 12.LinE,ChenMC,HuangCY,HsuSL,HuangWJ,LinMS,WuJCH,LinH*2014All-transretinoicacidinducesDU145cellcyclearrestthroughCdk5activation,CellularPhysiologyandBiochemistry.vol.33,pp.1620-1630.(SCI) 13.HsuFN,ChenMC,LinKC,PengYT,LiPC,LinE,ChiangMC,HsiehJT,andLinH*2013Cyclin-dependentkinase5modulatesSTAT3andandrogenreceptoractivationthroughphosphorylationofSer727onSTAT3onprostatecancercells,AmericanJournalofPhysiology-EndocrinologyandMetabolism.vol.305,pp.E975-E986.(SCI) 14.HuangPH,HuangCY,ChenMC,LeeYT,YueCH,WangHY,andLinH*2013Emodinandaloe-emodinsuppressbreastcancercellproliferationthroughERαinhibition,Evidence-basedComplementaryandAlternativeMedicine.vol.2013,pp.376123.(SCI) 15.HsiaoHB,LinH,WuJB,andLinWC2013Kinsenosidepreventsovariectomy-inducedbonelossandsuppressesosteoclastogenesisbyregulatingclassicalNF-κBpathways,OsteoporosisInternational,24.pp.1663-1676.(SCI) 16.LinE,LinH,HungGU,WuJCH,HsiehHL,LinTC,ChenCC,WangCH,LinMS2013Spontaneousruptureofthebladderafteraseizure,apitfallofdiagnosis.SurgicalScience,4. 17.WangHY,LinWY,ChenMC,LinT,ChaoCH,HsuFN,LinE,HuangCY,LuoTY,andLinH*2013InhibitoryeffectsofRhenium-188-labeledHerceptinonprostatecancercellgrowth,apossibleradioimmunotherapytoprostatecarcinoma.InternationalJournalofRadiationBiology,89.no.1,pp.346-355.(SCI) 18.ChenMC,HuangCY,HsuSL,LinE,KuCT,LinH*,andChenCM*2012RetinoicacidinducesapoptosisofprostatecancerDU145cellsthroughCdk5over-activation,ECAM,2012:580736.no.1.(SCI) 19.LinHY,YehWL,HuangBR,LinC,LaiCH,LinH*,andLuDY*2012Desipramineprotectsneuronalcelldeathandinduceshemeoxygenase-1expressioninMes23.5dopaminergicneurons,PLoSOne,7:e50138.(SCI) 20.LinHandWangPS2012InhibitoryeffectsofdigoxinontestosteroneproductioninratLeydigcells,AdaptiveMedicine,4.pp.165-172. 21.ChangCT,HoTY,LinH,LiangJA,HuangHC,LiCC,LoHY,WuSL,HuangYF,andHsiangCY20125-FluorouracilinducedintestinalmucositisvianuclearFactor-kappaBactivationbytranscriptomicanalysisandinvivobioluminescenceimaging,PLoSOne,7:e31808.(SCI) 22.LeeYT*,LinH,GuoJC,YanSL,HouHJ,LaiYS,LiuYH,WuHS,andHwangMH2012Laparoscopy-assistedBillrothIgastrectomyforectopicpancreasintheprepyloricregion,CaseReportofGastroenterology,6.pp.712-719. 23.HsuFN,ChenMC,ChiangMC,LinE,LeeYT,HuangPH,LeeGS,LinH*2011Regulationofandrogenreceptorandprostatecancergrowthbycyclin-dependentkinase5,JournalofBiologicalChemistry,286.pp.33141-33149.(SCI) 24.HsiaoHB,WuJB,LinH,LinWC*.2011KinsenosideisolatedfromAnoectochilusformosanussuppresseslipopolysaccharide-stimulatedinflammatoryreactionsinmacrophagesandendotoxinshockinmice,Shock,35.pp.184-190. 25.ChangCT,LinH,HoTY,LiCC,LoHY,WuSL,HuangYF,LiangJA,HsiangCY2011Comprehensiveassessmentofhostresponsestoionizingradiationbynuclearfactor-κBbioluminescenceimaging-guidedtranscriptomicanalysis,PLoSOne,6:e23682.pp.IF:4.092.14.1%.(SCI) 26.HsuFN,YangMS,LinE,TsengCF,LinH*.2011ThesignificanceofHer2onandrogenreceptorproteinstabilityinthetransitionofandrogenrequirementinprostatecancercells,AmericanJournalofPhysiology-EndocrinologyandMetabolism,300.pp.E902-E908. 27.LienHM,KuoPT,HuangCL,KaoJY,LinH,YangDY,LaiYY.2011Studyoftheanti-proliferativeactivityof5-substituted4,7-dimethoxy-1,3-benzodioxolederivitivesofSY-1fromAntrodiacamphorateonhumanCOLO205coloncancercells,ECAM,2011:450526.no.1.(SCI) 28.ChenCH,LinH,ChuangSM,LinSY,ChenJJW2010AcidicstressfacilitatestyrosinephosphorylationofHLJ1toassociatewithactincytoskeletoninlungcancercells,ExperimentalCellResearch,316:.pp.2910-2921. 29.LeeYT,LinH,ChenKY,WuHS,HwangMH,YanSL2010Life-threateninghemobiliacausedbyhepaticpseudoaneurysmafterT-tubecholedochostomy:reportofacase,BMCGastroenterology,10:81. 30.ChenMC,LinH,HsuFN,HuangPH,LeeGS,WangPS2010TheinvolvementofcAMPinnervegrowthfactor-triggeredp35/Cdk5activationanddifferentiationinPC12cells,AmericanJournalofPhysiology-CellPhysiology.pp.C516-C527.(SCI) 31.KuoHS,Hsu,FN,ChiangMC,YouSC,ChenMC,LoMJ,andLinH*2009RetinoicacidcausesCdk5-dependentapoptosisofcervicalcancercellline,ChineseJournalofPhysiology,52.pp.23-30.(SCI) 32.LinH*,ChenMC,andKuCT2009Cdk5regulatessteroidogenicacuteregulatoryprotein(StAR)andandrogenproductioninmouseLeydigcellsEndocrinology,150,pp.396-403.(SCI) 33.LinH2009Theversatilerolesofcyclin-dependentkinase5inhumandiseases,AdaptiveMedicine,1.pp.22-25. 34.LeeWJ,WuCS,LinH,LeeIT,WuCM,TsengJJ,ChouMM,andSheuWHH2009Visfatin-inducedexpressionofinflammatorymediatorsinhumanendothelialcellsthroughtheNF-kBpathwayInternatioanlJournalofObesity33,pp.465-472.(SCI) 35.YanSL,LinH,KuoCL,WuHS,HuangMH,andLeeYT2008Primaryretroperitonealmucinouscystadenoma,reportofacaseandreviewoftheliteratureWorldJournalofGastroenterology,14.pp.5769-5772. 36.LeeYT,LinH,WuHS,KuoCL,HwangMA,TsengYC,andHwangMH2008Largeepidermoidcystofthebreast:reportofacaseFormosanJournalofSurgery41,pp.221-225.(SCI) 37.LinE,LinH,LinMS,WuJCH,ChenWC,ChiuAW2008Laparoscopicexcisionofaparagangliomalocatedintherenalarteriovenouswindows-areasonableapproach,TheOpenUrology&NephrologyJournal,1.pp.40-43. 38.LinH*,ChenMC,ChiuCY,SongYM,andLinSY2007Cdk5regulatesSTAT3activationandcellproliferationinmedullarythyroidcarcinomacells,JournalofBiologicalChemistry282.pp.2776-2784.(SCI) 39.LinH,LinTY,andJuangJL*.2007AblderegulatesCdk5kinaseactivityandsubcellularlocalizationforamyloid-inducedDrosophilaneuCellDeath&Differentiation14,pp.607-615.(SCI) 40.LinH,JuangJL*,andWangPS*2004InvolvementofCdk5/p25indigoxin-triggeredprostatecancercellapoptosis.JournalofBiologicalChemistry279,pp.29302-29307.(SCI) 41.LinH,WangSW,WangRY,andWangPS*.2001StimulatoryeffectoflactateontestosteroneproductionbyratLeydigcells,JournalofCellularBiochemistry83.pp.147-154.(SCI) 42.LinH,ChienCH,LinYL,ChenCF,andWangPS*.2000InhibitionoftestosteronesecretionbyS-petasininrattesticularinterstitialcells,ChineseJournalofPhysiology43.pp.99-103.(SCI) 43.ChiaoYC,LinH,WangSW,andWangPS*.2000Directeffectsofpropylthiouracilontestosteronesecretioninrattesticularinterstitialcells,BritishJournalofPharmacology130.pp.1477-1482.(SCI) 44.ChangLL,LoMJ,KanSF,HuangWJ,ChenJJ,KauMM,WangJL,LinH,TsaiSC,ChiaoYC,YehJY,WunWS,andWangPS*1999Directeffectsofprolactinoncorticosteronereleasebyzonafasciculata-reticulariscellsfrommalJournalofCellularBiochemistry73,pp.563-572.(SCI) 45.LinH,TsaiSC,ChenJJ,ChiaoYC,WangSW,WangGJ,ChenCF,andWangPS*.1999Effectsofevodiamineonthesecretionoftestosteroneinrattesticularinterstitialcells,Metabolism48.pp.1532-1535.(SCI) 46.HuangWJ,YehJY,TsaiSC,LinH,ChiaoYC,ChenJJ,LuCC,HwangSW,WangSW,ChangLS,andWangPS*.1999Regulationoftestosteronesecretionbyprolactininmalerats,JournalofCellularBiochemistry74.pp.111-118.(SCI) 47.KauMM,LoMJ,WangSW,TsaiSC,ChenJJ,ChiaoYC,YehJY,LinH,ShumAY,FangVS,HoLT,andWangPS*.1999Inhibitionofaldosteroneproductionbytestoteroneinmalerats.,Metabolism48.pp.1108-1114.(SCI) 48.LoMJ,KauMM,ChenJJ,YehJY,LinH,WangSW,andWangPS1999Age-relateddifferencesincorticosteronesecretioninfemalerats,Metabolism48.pp.535-541.(SCI) 49.KauMM,LoMJ,TsaiSC,ChenJJ,LuCC,LinH,WangSW,andWangPS*.1999Effectsofestradiolonaldosteronesecretioninovariectomizedrats,JournalofCellularBiochemistry73.pp.137-144.(SCI) 50.WangSW,LinH,HwangWJ,andWangPS*1999Inhibitionoftestosteronesecretionbydigitoxininrattesticularinterstitialcell,JournalofCellularBiochemistry74.pp.74-80.(SCI) 51.LinH,WangSW,TsaiSC,ChenJJ,ChiaoYC,LuCC,HuangWJ,WangGJ,ChenCFandWangPS*1998InhibitoryeffectofdigoxinontestosteronesecretionthroughmechanismsinvolvingdecreasesofcycBritishJournalofPharmacology125,pp.1635-1640.(SCI) 52.WangSW,LinH,TsaiSC,HwuCM,ChiaoYC,LuCC,ChenJJ,WangGJ,ChouCJ,LinLC,andWangPS*.1998EffectsofmethanolextractofChansuonthehypothalamic-pituitary-testisfunctioninrats,Metabolism47.pp.1211-1216.(SCI) 53.DoongML,LuCC,KauMM,TsaiSC,ChiaoYC,ChenJJ,YehJY,LinH,HuangSW,ChenTS,ChangFY,andWangPS*1998InhibitionofgastricemptyingandintestinaltransitbyamphetaminethroughamechanisminvolvingaBritishJournalofPharmacology124,pp.1123-1130.(SCI) 54.TsaiSC,ChenJJ,ChiaoYC,LuCC,LinH,YehJY,LoMJ,KauMM,WangSW,andWangPS*.1997TheroleofcyclicAMPproduction,calciumchannelactivationandenzymeactivitiesintheinhibitioBritishJournalofPharmacology122.pp.949-955.(SCI) 55.WangSW,ChiaoYC,TsaiSC,LuCC,ChenJJ,ShihHC,ChenYH,LinH,HwuCM,andWangPS1997Inhibitionofbufalinonpituitaryandtesticularfunctioninrats,JournalofPharmacologyandExperimentalTherapy283.pp.528-532.(SCI) B.研討會論文  1.YangMS,HsuFN,andLinH*20082008Changesofsurvivalsignalingsbetweenandrogen-dependentand-independnetstatusinprostatecancercells,The23thJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March29~30.(OralSession#44). 2.Lee,GSandLinH*.20082008RoscovitineinhibitsproliferationofprostatecancercellspossiblythroughCdk5inhibition,The23thJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March29~30.(OralSession#8). 3.LiuCY,LinLL,ChiangMC,LinH*.20082008TheroleofEGFRtranslocationinprostatecancercells,The23thJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March29~30.(OralSession#6). 4.LinLL,HsuFN,andLinH*.20082008Cdk5interferescyclinD1-dependentregulationofandrogenreceptor,The23thJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March29~30. 5.YouSC,KuoHS,LinLL,andLinH*.20072007All-trans-RetinoicAcid(RA)-inducedproteininteractionbetweenCdk5andp21CIP1promoteG1arrest15thSymposiumonRecentAdvancesinCellularandMolecularBiology,Kenting,Taiwan,1-3,February,2007.(Poster#80). 6.LinH*,ChenMC,andWangPS20072007NicotinedecreasestestosteroneproductionandLeydigcellviabilitythroughCdk5hyperactivation.ProgramandAbstractofthe40thAnnualMeetingoftheSocietyfortheStudyofReproduction,SanAntonio,USA21-25,July,2007.(poster#414). 7.ChiuCY,PengHC,andLinH*.20072007Theroleofcdk5inGDNF-inducedproliferationofhumanmedullarythyroidcarcinomacells,The22ndJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March17~18,2007.(OralSession#002). 8.HsuFN,LinLL,HuangWH,andLinH*20072007Cdk5regulatesproliferationofprostatecancer5\r\ncellsthroughandrogenreceptorphosphorylation15thSymposiumonRecentAdvancesinCellularandMolecularBiology,Kenting,Taiwan,1-3,February,2007.(Poster#74). 9.ChenCCandLinH20062006Therolepfp35/Cdk5inN-cadherin/beta-catenin-relatedadhesioninprostatecancercells,The21thJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March18~19.(PosterSession#504). 10.KuCT,ChiuCY,YouSC,andLinH.20062006Retinoicacid-induceddifferentiationofprostatecancercellline,DU145,isthroughupergulationoThe21thJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March18~19. 11.KuoHS,ChiangMC,TsengSH,andLinH.20062006RelationshipbetweenCdk5/p35andp53proteinsinretinoicacid-induceddifferentiationofHeLacellThe21thJointAnnualConferenceofBiochemicalScience,Taipei,Taiwan,March18~19.(PosterSession#294). 12.TsengCF,HsuFN,andLinH.20062006TheinvolvementofCdk5andp35inHer2/ErbB3-dependentandrogenreceptorsignalingpathway,The21thJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March18~19.(OralSession#028). 13.LiGS,TsaiSY,andLinH.20062006TheroleofCdk5/p35inNGF-induceddifferentiationofPC12,The21thJointAnnualConferenceofBiochemicalScience.Taipei,Taiwan,March18~19.(PosterSession#313). 14.LinH,ChenMC20052005Thebiologicalfunctionsofcyclin-dependentkinase5andp35proteininandrogenproductionofmousProgramandAbstractofthe38thAnnualMeetingoftheSocietyfortheStudyofReproduction,Quebec,Cananda.24-27,July,2005(Program#751). 15.LinH.20052005Therolesofcdk5andp35proteininandrogenproductionofmouseleydigcells,The20thJointAnnualConferenceofBiochemicalScience. 16.LinH,ChenMC,JuangJL,andWangPS20042004Apossiblecurativeeffectofdigoxinonprostatecancer,TwelfthInternationalCongressofEndocrinology,Lisbon,Portugal.August31~September4(OralSession#16).