蘇鴻麟 - 中興大學生命科學系
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神經幹細胞實驗室 ... 實驗室位置:, 402台中市南區國光路250號生命科學大樓6F 603實驗室 ... 國立中興大學, 生物科技發展中心, 服務推廣組組長, 2011.08-2013,01. 蘇鴻麟[教授] 神經幹細胞實驗室 辦公室電話: (04)22840416#605 實驗室電話: (04)22840416#604 傳   真 : (04)22854391 實驗室位置: 402台中市南區國光路250號生命科學大樓6F603實驗室 最高學歷 : 國防醫學院生命科學研究所博士 專長領域 : 胚胎幹細胞、神經科學、病毒學、細胞生物學 電子信箱 : [email protected];[email protected] 實驗室網站: https://orcid.org/0000-0001-7734-3499 學歷 經歷 研究方向 開設課程 研究室人員 學術著作 年份 標題 2020 中興大學產學績優教師 2019 中興大學產學績優教師科技部大醫工學門複審委員 2018 中興大學產學績優教師 2017 國家新創獎 2017 興大創新研發成果卓越獎 2017 中興大學產學績優教師 2016 中興大學產學績優教師 2015 中興大學產學績優教師 2015 科技部幹細胞、醫工、骨科學門複審委員 2014 中興大學研究績優教師 2013 EditorialBoardmemberofBiomedResearchInternational 2013 第六屆臺法前鋒科學論壇國際成員養成會議 2012 台灣幹細胞學會理事委員 2012 EditorialboardmemberofCellTransplantation 2010 中興大學傑出貢獻獎 2009 中興大學傑出青年教師獎 畢業學校 主修學門系所 學位 時期 國防醫學院 生命科學研究所 博士 1997-2001 國防醫學院 微生物及免疫學研究所 碩士 1995-1997 台灣大學 獸醫學系 學士 1988-1993 服務機關 服務部門 職稱 時期 中興大學生命科學系 生命科學系 教授 2013,08- 中興大學 生物科技發展中心 研發組組長 2013,02-2015,01.31 國立中興大學 生物科技發展中心 服務推廣組組長 2011.08-2013,01 國立中興大學 生命科學系 副教授 2010,08-2013,07 國立中興大學 生命科學系 助理教授 2005,02-2010,07 日本財團法人先端醫療振興財團 事業化推進部 主任研究員 2002-2005 日本理化學研究所 發生‧再生科學總合研究中心 訪問研究員 2002-2005 國立中山大學 生物醫學研究所 博士後研究員 2001-2002 研究興趣1.遺傳性與退化性神經疾病之細胞模式的建立2.由胚胎幹細胞分化成為特定的神經細胞,如多巴胺神經細胞與運動神經細胞3.體外粒線體的遞送與治療4.幹細胞培養基的開發研究主題1.胚胎幹細胞與iPS的神經分化2.臨床用培養基的開發3.粒線體遞送與疾病治療研究計畫科技部支持之價創計畫、育苗計畫與個人型研究計畫 博士班黃隆永林智堯吳詩芳蔡昇峰碩士班大學部研究助理江承運博士後研究申靜懿畢業生洪達任(碩96畢),高榮惠(碩96肄)、包翊絹(碩97畢),黃柏瑞(碩97畢),張兆嶔(碩97畢),吳雅婷(碩98畢),林智堯(碩98畢),張嘉佑(碩98畢),林秀鴻(碩99畢),丁筱茜(碩99畢),喬書荷(碩100畢),陳嬿如(碩101畢),蔡詠任(碩101畢),阮植垠(碩101畢),張菀婷(碩101畢),陳靜雯(博100畢),郭淑明(博100畢),陳聖美(博101畢),劉人瑋(博102畢),曾莉萍(博士後研究員),李琇琴(博102肄),吳詩芳(碩102畢),沈博文(碩102畢),陳姵穎(碩102畢),葉文瑜(碩102畢),陳逸茵(碩102畢),曾學敏(碩103畢),張滋麟(碩103畢),賴正國(博103畢),蔡筱琪(博103畢),黃柏瑞(博104畢),申仕政(博103畢),張嘉佑(博104畢),郭珊珊(碩104畢),黃隆永(碩106畢),楊雅晴(碩106畢),江承運(碩106畢),郭啟中(博105畢),莊介森(博106畢),黃逸軒(碩107畢),張㚬瑋(碩107畢),胡智勝(碩108畢),李亦可(碩108畢),黃茂軒(博108畢),莊弘盟(博106畢) A.期刊論文 1.Wang,H.M.,Fu,L,,Cheng,C.C.,Gao,R.,Lin,M.Y.,Su,H.L.,Belinda,N.E.,Nguyen,T.H.,Lin,W.H.,Lee,P.C.,Hsieh,L.P.2019InhibitionofLPSInducedOxidativeDamagesandPotentialAnti-InflammatoryEffectsofPhyllanthusemblicaExtractviaDown-RegulatingNF-κB,COX-2,andiNOSinRAW264.7Cells..,Antioxidants(Basel),8(8),E270... 2.Huang,M,H,,Chou,Y,W,,Li,M.H.,Shih,T.E.,Lin,S.Z.,Chuang,H.M.,Chiou,T.W.,Su,H.L.,Harn,H.J.2019EpigenetictargetingDNMT1ofpancreaticductaladenocarcinomausinginterstitialcontrolreleasebiodegradingpolymereducedtumorgrowththroughhedgehogpathwayinhibition.,PharmacologicalResearch.,139,50-61... 3.Chen,Y.J.,Cheng,F.C.,Chen,C.J.,Su,H.L.,Sheu,M.L.,Sheehan,J.,Pan,H.C.2019Down-RegulatedExpressionofMagnesiumTransporterGenesFollowingaHighMagnesiumDietAttenuatesSciaticNerveCrushInjury.,Neurosurgery,84,965-976.. 4.Su,H.L.,Chiang,C.Y.,Lu,Z.H.,Cheng,F.C.,Chen,C.J.,Sheu,M.L.,Sheehan,J.,Pan,H.C.2018Lateadministrationofhigh-frequencyelectricalstimulationincreasesnerveregenerationwithoutaggravatingneuropathicpaininanervecrushinjury.e,BMCNeuroscience,19,37.. 5.Sheu,M.L.,Chiang,C.Y.,Su,H.L.,Chen,C.J.,Sheehan,J.,Pan,H.C.2018IntrathecalInjectionofDualZipperKinaseshRNAAlleviatingtheNeuropathicPaininaChronicConstrictiveNerveInjuryModel.,InternationalJournalofMolecularSciences,19,2421.. 6.Liu,C.A.,Chang,C.Y.,Hsueh,K.W.,Su,H.L.,Chiou,T.W.,Lin,S.Z.,Harn,H.J.2018Migration/InvasionofMalignantGliomasandImplicationsforTherapeuticTreatment.,InternationalJournalofMolecularSciences,19,1115...(SCI) 7.Chuang,H.M.,Ho,L.I.,Huang,M.H.,Huang,K.L.,Chiou,T.W.,Lin,S.Z.,SuH.L.,Harn,H.J.,2018Non-CanonicalRegulationofTypeICollagenthroughPromoterBindingofSOX2andItsContributiontoAmelioratingPulmonyFibrosisbyButylidenephthalide..nary,InternationalJournalofMolecularSciences.vol.19,3024..(SCI) 8.Chang,C.Y.,Ting,H.C.,Su,H.L.,Jeng,J.R.2018CombiningInducedPluripotentStemCellsandGenomeEditingTechnologiesforClinicalApplications.,CellTransplantation,27,379-392... 9.Chang,C.Y.,Ting,H.C.,Liu,C.A.,Su,H.L.,Chiou,T.W.,Harn,H.J.,Lin,S.Z.2018InducedPluripotentStemCells:APowerfulNeurodegenerativeDiseaseModelingToolforMechanismStudyandDrugDiscovery..,CellTransplantation.vol.doi:10.1177/0963689718775406. 10.Tsai,S.F.Tao,M.Ho,L.I.Chiou,T.W.Lin,S.Z.Su,H.L.*Harn,H.J.*2017Isochaihulactone-inducedDDIT3causesERstress-PERKindependentapoptosisinglioblastomamultiformecells.,Oncotarget,8(3):4051-4061.(SCI) 11.Kuo,C.C.Su,H.L.Chang,T.L.Chiang,C.Y.Sheu,M.L.Cheng,F.C.Chen,C.J.Sheehan,J.Pan,H.C.2017PreventionofAxonalDegenerationbyPerineuriumInjectionofMitochondriainaSciaticNerveCrushInjuryModel.,Neurosurgery,80(3):475-488.. 12.Hsieh,M.H.Meng,W.Y.Liao,W.C.Weng,J.C.Li,H.H.Su,H.L.Lin,C.L.Hung,C.S.Ho,Y.J.2017CeftriaxonereversesdeficitsofbehaviorandneurogenesisinanMPTP-inducedratmodelofParkinson'sdiseasedementia.,BrainResBull,132:129-138..(SCI) 13.Chuang,C.S.Su,H.L.Lin,C.L.Kao,C.H.2017RiskofParkinsondiseaseafterorganophosphateorcarbamatepoisoning,ActaNeurolScand,136(2):129-137.. 14.Chuang,C.S.Chang,J.C.Cheng,F.C.Liu,K.H.Su,H.L.*Liu,C.S.*2017ModulationofmitochondrialdynamicsbytreadmilltrainingtoimprovegaitandmitochondrialdeficiencyinaratmodelofParkinson'sdisease,LifeSciences,.vol.191:236-244.. 15.Chang,J.C.,S.L.Wu,K.H.Liu,Y.H.Chen,C.S.Chuang,F.C.Cheng,H.L.Su,Y.H.Wei,S.J.Kuo,andC.S.Liu,2016Allogeneic/xenogeneictransplantationofpeptide-labeledmitochondriainParkinson'sdisease:restorationofmitochondriafunctionsandattenuationof6-hydroxydopamine-inducedneurotoxicity.,TranslRes,.vol.170,pp.40-56.(SCI) 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30.Systemiccombinedmelatonin-mitochondriatreatmentimprovesacuterespiratorydistresssyndromeintherat.2015GalanginPreventsAcuteHepatorenalToxicityinNovelPropacetamol-InducedAcetaminophen-OverdosedMice.,J.MedFood.vol.18,no.11,pp.1187-97..(SCI) 31.TsaiHC,SuHL,HuangCY,FongYC,HsuCJ,TangCH.2014/06CTGFincreasesmatrixmetalloproteinasesexpressionandsubsequentlypromotestumormetastasisinhumanosteosarcomathroughdown-regulatingmiR-519d.,Oncotarget.vol.5,no.11,pp.3800-12. 32.TsengLP,JuanCY,LinSL,DoranMR,LinJJ,HsuSH,LiaoJW,ShenCIandSuHL*.2014/05NanohybridsofsilverparticlesonclayplateletsdelaminatePseudomonasbiofilms,Nanomedicine(Lond).vol.9,no.6,pp.803-17. 33.TsaiHC,HuangCY,SuHLandTangCH2014/05CTGFincreasesdrugresistancetopaclitaxelbyupregulating1survivinexpressioninhumanosteosarcomacells,BBA-MolecularCellResearch.vol.1843,no.5,pp.846-54.(SCI) 34.ChenYJ,ChengFC,SheuML,SuHL,ChenCJ,SheehanJ,PanHC2014/04DetectionofsubtleneurologicalalterationsbytheCatwalkXTgaitanalysissystem.,J.NeuroengRehabil..vol.11,pp.62. 35.TsaiHC,HuangCY,SuHL,TangCH.2014/03CCN2enhancesresistancetocisplatin-mediatingcellapoptosisinhumanosteosarcoma.,PLoSOne.vol.9,no.3,pp.e90159. 36.ChiangCY,SheuML,ChengFC,ChenCJ,SuHL,SheehanJ,PanHC.2014/01ComprehensiveanalysisofneurobehaviorassociatedwithhistomorphologicalalterationsinachronicconstrictivenerveinjurymodelthroughuseoftheCatWalkXTsystem.,J.Neurosurg..vol.120,no.1,pp.250-62.. 37.KuoCH,LuCY,YangYC,ChinC,WengBC,LiuCJ,ChenYH,ChangLL,KuoFC,WuDC,SuHL2014Doeslong-termuseofsilvernanoparticleshavepersistentinhibitoryeffectonH.pyloribasedonMongoliangerbil'smodel?,BiomedResInt.vol.2014,pp.461034. 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46.LaiCH,LaiCK,LinYJ,HungCL,ChuCH,FengCL,ChangCSandSuHL*.2013/06Characterizationofputativecholesterolrecognition/1interactionaminoacidconsensus-likemotifofCampylobacterjejunicytolethaldistendingtoxinC,PLoSONE.vol.8,no.6,pp.e66202. 47.KuoSM,KaoHW,HouMH,WangCH,LinSHandSuHL*2013EvolutionofinfectiousbronchitisvirusinTaiwan,positivelyselectedsitesinthenucleocapsidproteinandtheireffectsonRNA-bindingactivity.VetMicrobiol.162.pp.408-18. 48.Cheng,FC,Sheu,ML,SuHL,Chen,YJ,Chen,CJ,Chiu,WT,Sheehan,J.andPan,HC2013TheeffectofexerciseonmobilizationofhematopoieticprogenitorcellsinvolvedintherepairofsciaticnervecrushinjuryJ,Neurosurgury.118(3):.pp.594-605.. 49.LiuJW,HsuYC,KaoCY,SuHL*.,ChiuIM*.2013LIF-inducedStat3signalingsuppressesFGF1-inducedErk1/2activationtoinhibitthedownstreamdifferentiationinmouseembryonicstemcells,StemCellsDev.22(8):.pp.1190-7. 50.KuoCC,TsaiHY,LinJG,SuHL.,ChenYF2013SpinalSerotonergicandOpioidReceptorsAreInvolvedinElectroacupuncture-InducedAntinociceptionatDifferentFrequenciesonZuSanLi(ST36)Acupoint,EvidBasedComplementAlternatMed..vol.2013,pp.291972. 51.HuangCP,ChenHN,SuHL.,HsiehCL,ChenWH,LaiZR,LinYW2013ElectroacupunctureReducesCarrageenan-andCFA-InducedInflammatoryPainAccompaniedbyChangingtheExpressionofNav1.7andNav1.8,ratherthanNav1.9,inMiceDorsalRootGanglia,EvidBasedComplementAlternatMed.2013:312184. 52.LuHE,YangYC,ChenSM,SuHL,HuangPC,TsaiMS,WangTH,TsengCP,HwangSM2012ModelingNeurogenesisImpairmentinDownSyndromewithInducedPluripotentStemCellsfromTrisomy21AmnioticFluidCellsExp,CellRes.319(4).pp.498-505. 53.YangDY,SheuML,SuHL.ChengFC,ChenYJ,ChenCJ,ChiuWT,YiinJJ,SheehanJ,PanHC2012Dualregenerationofmuscleandnervebyintravenousadministrationofhumanamnioticfluid-derivedmesenchymalstemcellsregulatedbystromalcell-derivedfactor-1αinasciaticnerveinjurymodel,JNeurosurg.116(6).pp.1357-67. 54.ChiaoSH,LinSH,ShenCI,LiaoJW,BauIJ,WeiJC,TsengLP,HsuSH,LaiPS,LinSZ,LinJJ*andSuHL*2012EfficacyandSafetyofNanohybridsComprisingSilverNanoparticlesandSilicateClayforControllingSalmonellaInfectionInt,Int.J.Nanomed.7:.pp.2421-32. 55.SheuML,ChengFC,SuHL,Ying-JuChenYJ,ChenCJ,ChiangCM,ChiuWT,SheehanJandPanHC2012RecruitmentbySDF-1αofCD34-positivecellsinvolvedinsciaticnerveregeneration,JNeurosurg.116(2).pp.432-44. 56.LaiCY,OuYC,ChangCY,PanHC,ChangCJ,LiaoSL,SuHL*andChenCJ*2012EndothelialJapaneseencephalitisvirusinfectionenhancesmigrationandadhesionofleukocytestobrainmicrovascularendotheliaviaMEK-dependentexpressionofICAM1andtheCINCandRANTESchemokines,J.Neurochem.123(2):.pp.250-261. 57.ShenCI,WangCH,ShenSC,LeeHC,LiaoJW*andSuHL*.2011TheinfectionofchickentrachealepithelialcellswithaH6N1avianinfluenzavirus,PLoSONE.6(5):e18894. 58.LinML,LuYC,SuHL,LinHT,LeeCC,KangSE,LaiTC,ChungJG,andChenSS2011DestabilizationofCARPmRNAsbyAloe-EmodinContributestoCaspase-8–Mediatedp53-IndependentApoptosisofHumanCarcinomaCellsJ,Cell.Biochem.112.pp.1176-91. 59.ChangCY,ShenCC,SuHL*,ChenCJ*2011GefitinibinducesapoptosisinhumangliomacellsviatargetingBadphosphorylationJ,Neuro-Oncology.105(3).pp.507-22. 60.SuHL*,LinSH,WeiJC,PaoIC,ChiaoSH,HuangCC,LinSZandLinJJ*2011NovelNanohybridsofSilverParticlesonClayPlateletsforInhibitingSilver-ResistantBacteriaPLoSONE.6(6):e2112. 61.PanHC,SheuML,SuHL.ChenYJ,ChenCJ,YangDY,ChiuWT,ChengFC2011MagnesiumSupplementPromotesSciaticNerveRegenerationandDown-regulatesInflammatoryResponse,MagnesiumResearch.24(2):.pp.54-70. 62.PanHC,WuYT,ShenSC,WangCC,TsaiMS,ChengFC,LinSZ,ChenCW,LiuCSandSuHL*.2011CharacterizationofAxonFormationintheEmbryonicStemCell-DerivedMotoneuron,CellTransplantation.20(4):.pp.493-502. 63.LinCD,LaiCK,LinYH,HsiehJT,SingYT,ChangYC,ChenKC,WangWC,SuHL,LaiCH2011CholesterolDepletionReducesEntryofCampylobacterjejuniCytolethalDistendingToxinandAttenuatesIntoxicationofHostCells,InfectImmun.79(9):.pp.3563-75. 64.WeiJC,YenYT,SuHL,LinJJ.2011InhibitionofbacterialgrowthbytheexfoliatedclaysandobservationofphysicalcapturingmechanismJ,Phy.Chem.C,115,.pp.18770-75. 65.ShenCI,WangCH,LiaoJW,HsuTW,KuoSMandSuHL*.2010Theinfectionofprimaryaviantrachealepithelialcellswithinfectiousbronchitisvirus,Vet.Res.41:06.. 66.ChenCW,LiuCS,ChiuIM,ShenSC,PanHC,LeeKH,LinSZandSuHL*.2010ThesignalsofFGFsontheneurogenesisofembryonicstemcells,J.Biomed.Sci.17:33.. 67.LiPR,WeiJC,ChiuYF,SuHL.PengFC,LinJJ.2010Evaluationoncytotoxicityandgenotoxicityoftheexfoliatedsilicatenanoclay,ACSApplMaterInterfaces.2:.pp.1608-13. 68.KuoSM,WangCH,HouMH,HuangYP,KaoHWandSuHL*.2010EvolutionofinfectiousbronchitisvirusinTaiwan,CharacterisationofRNArecombinationinthenucleocapsidgene.Vet.Microbiol.144:.pp.293-302.. 69.ChuangCS,SuHL,ChengFC,HsuS,ChuangCF,andLiuCS2010QuantitativeEvaluationofMotorFunctionBeforeandAfterEngraftmentofDopaminergicNeuronsinaRatModelofParkinson'sDisease,J.Biomed.Sci.17:9.. 70.SuHL*,ChouCC,HungDJ,LinSH,PaoIC,LinJH,HuangFL,DongRXandLinJJ*.2009TheDisruptionofBacterialMembraneIntegritythroughROSGenerationInducedbyNanohybridsofSilverandClay,Biomaterials.30:.pp.5979-5987. 71.ChangJC,HsuSH*andSuHL2009Theregulationofthegapjunctionofhumanmesenchymalstemcellsthroughtheinternalizationofquantumdots,Biomaterials.30:1937-1946.IF=7.9. 72.ChangJC,SuHLandHsuSH.2008Theuseofpeptide-deliverytoprotecthumanadipose-derivedadultstemcellsfromdamagecausedbytheinternalizationofquantumdots,Biomaterials.29.pp.925-936. 73.TsaoCH,SuHL,LinYL,YuHP,KuoSM,ShenCI,ChenCW.andLiaoCL*.2008Japaneseencephalitisvirusinfectionactivatescaspases-8and-9inFADD-independentandmitochondrion-dependentmanner,J.Gen.Virol.89,.pp.1930-41. 74.SuHL,MugurumaK,KengakuM,WatanabeKandSasaiY.2006GenerationofCerebellarNeuronPrecursorsfromEmbryonicStemCells,Dev.Biol.290:.pp.287-296. 75.SuHL,LiaoCLandLinYL2002Japaneseencephalitisvirusinfectioninitiatesendoplasmicreticulumstressandanunfoldedproteinresponse,JVirol.76:.pp.4162-71.
延伸文章資訊
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