陳全木 - 中興大學生命科學系

鳥禽遺傳資源暨動物生技研究中心_高教深耕特色中心計畫總主持人(教育部五年期計畫)_2018-2022。

... 下學期, 生物技術學(正課+實習), 3學分(選修), 生科系三年級. 陳全木[講座教授/終身特聘教授] 分子胚胎暨DNA甲基化研究室 辦公室電話： (04)22840319#701、(04)22856309 實驗室電話： (04)22840319#702 傳  &nbsp   真 ： (04)22874740 實驗室位置： 生命科學大樓701室 最高學歷 ： 國立台灣大學博士 專長領域 ： 分子胚胎學、羊水間葉幹細胞、基因轉殖動物科技、疾病動物模式、甲基化基因晶片、基因銘印機制、癌症生物學、功能性胜肽研究、表觀遺傳學  電子信箱 ： [email protected] 實驗室網站： https://orcid.org/0000-0003-2461-9150    學歷 經歷 研究方向 開設課程 研究室人員 學術著作 年份 標題 2019.05 榮獲科技部107年度傑出研究獎 2018.07 榮獲2018日本APSBMS傑出研究成就獎 2017,12 榮獲2017年度教育部生技創新創業獎 2016,12 榮獲第十三屆國家新創獎(企業新創獎) 2016,12 指導碩士生(吳佩穎)獲第22屆台灣微生物學會論文競賽第一名 2016,11 指導碩士生(林煒峪)獲中華實驗動物學會第十四屆學術研討會壁報論文競賽優勝獎 2016,11 指導碩士生(陳彥廷)獲中華實驗動物學會第十四屆學術研討會壁報論文競賽優勝獎 2014.02 榮獲科技部102年度傑出研究獎 2013.12 榮獲國科會2013年農業生技產業化發展典範案例獎 2013.08 獲聘國立中興大學榮譽特聘教授 2012.10 榮獲2012年台北國際發明技術交易獎銀牌 2012.09 榮獲第九屆經濟部國家發明獎（生物醫學類) 2011.10 榮獲第十八屆東元科技獎 2011.09 榮獲國立中興大學100年度研究績優獎 2011.07 榮獲中興大學100年度特別貢獻獎 2011.08 榮獲美國動物生物科技2011年度傑出科學獎 2011.02 榮獲第三屆國家創新科技獎 2010.09 榮獲國立中興大學99年度建教合作績優獎 2010.09 榮獲第七屆經濟部國家發明獎（生物科技類） 2010.08 榮獲國立中興大學98年度特殊貢獻獎 2010.07 榮獲第四屆有庠科技發明獎（生醫製藥類) 2009.11 榮獲經濟部第二屆CrazyIdea應用王創意競賽佳作獎 2009.10 榮獲國立中興大學創業大賽優等獎 2009.09 榮獲國立中興大學98年度研發成果技術授權績優獎 2009.05 榮獲第五屆台灣幹細胞學會2009年度論文發表優勝獎 2008.10 榮獲2008經濟部CrazyIdea應用王創意競賽銅牌獎 2008.09 榮獲國立中興大學97年度建教合作績優獎 2007.09 獲聘國立中興大學特聘教授 2007.08 榮獲國立中興大學96年度優秀教育人員獎 2007.06 榮登首版亞洲科學名人錄 2007.03 榮獲國立金門高中科技類-傑出校友獎 2006.09 榮獲95年度中興大學研發成果技術轉移績優獎 2006.09 獲頒中華民國第四十四屆十大傑出青年 2006.02 獲頒第二屆總統農業創新獎 2005.06 榮獲第41屆日本肝癌研究年會SelectedPosterPresentationAward 2004.06 獲英國愛丁堡皇家學會海外訪問學者研究獎助 2004.05 榮獲中興大學九十二學年度青年教師研究獎 2002.09 獲美國EllisFischel癌症中心訪問學者獎助 2001.04 榮獲2001年美國癌症醫學年會最佳論文獎 2001.03 獲國科會科技人員國外短期研究獎助 2001 榮獲國科會甲種研究獎助 2001 榮獲金門縣立金沙國中傑出校友獎 2000 榮獲國科會甲種研究獎助 1999 榮獲國科會甲種研究獎助 1998 榮獲國科會甲種研究獎助 1997 榮獲國科會乙種研究獎助 1991 榮獲戈福江獎   畢業學校 主修學門系所 學位 時期 國立台灣大學 博士 1991/09-1995/05 國立台灣大學 學士 1987/09-1991/06   服務機關 服務部門 職稱 時期 國立中興大學 生命科學院 院長 2016/08-迄今 國立中興大學 生命科學系 講座教授 2021/08-迄今 國立金門大學 通識教育中心 講座教授 2015/08-迄今 教育部 資訊及科技教育司 顧問 2017/01-迄今 國立中興大學 生命科學系 終身特聘教授 2015/08-迄今 國立中興大學 轉譯醫學博士學位學程 特聘教授 2013/08-迄今 國際生物催化暨農業生物技術學會 (ISBAB) 常務理事 2013/01-迄今 中興大學-國衛院 組織工程與再生醫學博士學程 特聘教授/招生委員 2010/08-迄今 科技部 生命科學司 學門召集人 2015/01-2017/12 國立中興大學 研發處 研發長 2009/08-2016/01 國立中興大學 產學智財營運中心 中心主任 2011/01-2011/07 財團法人台灣動物科技研究所 諮議委員會 顧問 2009/01-2014/12 中興大學-中研院 微生物基因體學博士學程 特聘教授 2010/08-迄今 中研院-中興大學 分子暨生物農學國際博士學程 特聘教授 2007/08-迄今 國立陽明大學醫學院 臨床醫學研究所 兼任教授 2007/08-2009/07 國立中興大學 生命科學系 教授兼主任 2005/08-2009/07 國立中興大學 生技中心教學推動組 教授兼組長 2004/08-2008/07 英國愛丁堡大學醫學院 分子與臨床醫學中心 訪問教授 2004/06-2004/07 國立中興大學 生命科學系 副教授 2002/08-2004/08 美國EllisFischel 癌症研究中心 客座研究員 2001/09-2002/03 美國密蘇里大學醫學院 基因晶片中心 訪問教授 2001/03-2001/08 國立中興大學 動物學系 副教授 2000/08-2002/08 國立中興大學 動物學系 助理教授 1998/02-2000/07 國立中興大學 動物學系 講師 1996/08-1998/01 國立台灣大學 生殖育種研究室 博士後研究員 1995/08-1996/07   研究興趣1.基因轉殖複製動物培育技術之開發及其於生物醫學領域之研究應用2.影響哺乳動物胚早期發育階段發生之關鍵基因的篩選與功能之分析3.小鼠甲基化基因晶片之開發及其於發育生物學與腫瘤生物學之研究4.人類疾病動物模式開發(肺腺癌鼠、骨鬆症鼠、高血壓中風鼠、螢光/冷光鼠)5.功能性乳胜肽的開發與細胞及動物功效驗證6.羊水間葉幹細胞的誘導分化及其應用於細胞治療之研究研究主題1.小鼠CpGislands甲基化基因晶片之研發及其於肝癌基因之篩檢應用2.人類凝血因子基因轉殖動物之培育及其於血友病治療之應用3.含塵蟎過敏原基因之轉殖動物培育及其於新式口服性減敏療法之開發4.含人類hLPH乳糖分解酶之低乳糖乳基因轉殖動物研發及其於乳糖不耐症之應用5.控制胚早期發育之Granzyme關鍵基因的生理功能鑑定及分子調控機制6.抗骨質疏鬆症與骨關節炎之功能性胜肽研發及功效驗證7.表現綠螢光蛋白之羊水幹細胞於高氧肺損傷與肺纖維化的細胞治療研究曾執行之研究計畫*肝癌進行的病毒與腫瘤生物學因素：以新微陣列技術分析肝癌異常性甲基化與相關基因(3/3)(95-2321-B-010-005-)台-法國際合作計畫（合作對象：法國巴斯德研究院）。

*利用小鼠甲基化基因晶片剖析胚幹細胞於體外分化之機制(2/3)(95-2313-B-005-012-)國科會三年期計畫2005-2008。

*複製豬基因體組中銘印基因群上遺傳性修飾異常之研究(95-2313-B-005-030-MY3)國科會三年期計畫2006-2009。

*新式抗高血壓胜肽研究與商品雛形建構(96-2317-B-212-002-)國科會產學合作計畫。

*利用小鼠基因晶片剖析VEGF誘導基因轉殖鼠肺腫瘤生成之機制(97-2313-B-005-004-MY3)國科會三年期計畫2008-2011。

*表現VP1外鞘蛋白於基因轉殖動物乳汁:研發抗腸病毒71型新式口服疫苗(98-2321-B-005-006-MY3)國科會三年期計畫2009-2012。

*新式酪蛋白磷酸胜肽之研發及其於改善骨質疏鬆症之商品化應用(3/3)國科會三年期計畫2010-2013。

*利用乳腺表現型基因轉殖動物系統產製具生物活性之人類第八凝血因子B-區刪除重組蛋白(3/3)國科會三年期計畫2011-2014。

*利用過量表現人類血管內皮生長因子基因轉殖鼠模式探討不同物種乳鐵蛋白抑制肺部癌化之分子作用機轉(3/3)國科會三年期計畫2012-2015。

*豬乳鐵蛋白及其衍生抗菌胜肽之高效能量產與產業應用(1/4)科技部計畫2014-2018。

*新穎抗骨鬆胜肽於腸道細胞鈣離子吸收之機制及於骨質疏鬆動物治療模式之研究(1/3)科技部三年期計畫2015-2018。

目前進行之研究計畫*A型血友病動物模式之新式基因療法開發:以磁性奈米包膜材料作為核酸載體之功效評估(科技部三年期計畫)_2018-2021。

*建構Akr1A1基因剔除鼠之骨質疏鬆症動物模式作為新穎抗骨鬆胜肽開發之功效評估(科技部三年期計畫)_2019-2022。

*鳥禽遺傳資源暨動物生技研究中心_高教深耕特色中心計畫總主持人(教育部五年期計畫)_2018-2022。

  學期 科目名稱 學分 開設班級 下學期 動物基因轉殖技術學 2學分(選修) 博碩士班 下學期 遺傳學(正課+實驗) 4學分(必修) 生科系二年級 下學期 生物技術學(正課+實習) 3學分(選修) 生科系三年級 下學期 生命科學與工程 2學分(選修) 通識講座(材料系) 下學期 分子胚胎專題研究(二) 2學分(選修) 博碩士班 下學期 生物科技學特論 2學分(必修) 博士班 上學期 胚胎學 3學分(選修) 生科系三年級 上學期 生命科學與工程 3學分(選修) 通識講座(化工系) 上學期 生技產業暑期校外實習 1學分(選修) 博碩士班 上學期 分子生物學 4學分(必修) 生科系三年級 上學期 分子胚胎學專題研究(一) 2學分(選修) 博碩士班 上學期 生物科技產程 2學分(選修) 生科系四年級 現任博士後研究人員張若麟，籃英維，莊凱程歷任博士後研究人員童鈺棠(台北醫學大學代謝與肥胖科學研究所助理教授/中興大學生物科技研究所助理教授)蔡東州(豐展生物科技股份有限公司研發部經理)廖純惠陳勝義在學博士班生王俊隆、陳昱璇、陳建甫、賴仁傑、高永璁、柯祈化、楊小萱、吳婉如、江芸薇、陳世偉Ph.D.博士畢業生No.1楊勝舜(97博士畢；台中榮總胃腸科主治醫師、部定副教授）、No.2劉芳爵(97博士畢；行政院農委會新化畜試總所研究員)、No.3陳怡如(97博士畢；台中榮總醫院皮膚科主治醫師兼主任、陽明大學醫學系副教授)、No.4顏至慶(98博士畢；中國醫大胸腔科主治醫師、呼吸治療學系副教授)、No.5郭孟富(99博士肄；豐展生物科技股份有限公司總經理)、No.6洪哲明(99博士畢；行政院農委會新化畜試總所研究員)、No.7何國鼎(99博士畢；疾管局科技預官、台大醫學院博士後研究員)、No.8蔡東州(99博士畢；豐展生物科技股份有限公司研發部經理)、No.9陳俊宇(100博士畢;國家衛生研究院博士後研究員、中石化公司研發經理)、No.10賴紫綸(101博士畢;台中榮民總醫院、興大醫工所博士後研究員)、No.11沈志傑(101年博士畢；成功大學醫工所博士後研究員)、No.12黃景堂(101年博士畢；衛生福利部科技發展組研究員)、No.13林怡均(101年博士畢；中山醫學大學博士後研究員)、No.14蔡森蔚(102年博士畢；慈濟醫院復健科主治醫師兼主任)、No.15杜旻育(103年博士畢；國軍台中總醫院中清分院院長、國軍岡山分院副院長)No.16劉旭崇(104年博士畢；台中澄清醫院胸腔內科主治醫師、內科部副主任)、No.17賴政威(104年博士畢；生技公司研發人員)、No.18林怡伶(105年博士畢；台中榮民總醫院腸胃科博士級研究人員)、No.19劉佳宜(105年博士畢；仁德醫護專科學校護理科博士級講師)、No.20陳煒(105年博士畢；嘉義基督教醫院胸腔科主治醫師、醫院副院長)、No.21陳怡蒨(105年博士畢；資料未更新)、No.22鄒永恩(106年博士畢；中國醫大耳鼻喉部主治醫師兼喉科主任)、No.23羅文吉(107年博士畢；中國醫大醫學檢驗部組織庫醫檢師)、No.24郭嘉文(107年博士畢；國軍台中總醫院中清分院副院長、腎臟科主治醫師兼主任)、No.25林明鋒(107年博士肄；衛福部台中醫院泌尿科主治醫師兼主任)、No.26涂智彥(107年博士畢；中國醫大附設醫院胸腔科主治醫師兼主任)、No.27蔡新中(108年博士畢；衛福部台中醫院外科/醫美科主治醫師兼主任)、在學碩士班生張加妙、AbdulkadirCindem(Duka)、范瑞家、林楚倪、劉雅晴、張祐禎歷屆碩士畢業生王志宏(88碩士)，蔡文瑄(89碩士)，林殿威(89碩士)，林志成(89碩士)，盧建宇(90碩士)，白舜元(90碩士)，蔡淑惠(91碩士)，王立忠(91碩士)，魏杏芬(91碩士)，林怡君(92碩士)，余佳恆(92碩士)，陳彥伯(92碩士)，江敏瑜(93碩士)，沈志傑(93碩士)，黃文經(93碩士)，江敏瑜(93碩士)，劉家崙(93碩士)，黃俊諺(93碩士)，余秉純(93碩士)，黃國真(94碩士)，王妙鈴(94碩士)，蘇經貿(94碩士)，陳暐恩(95碩士)，賴政威(95碩士)，黃彬武(95碩士)，武揮凱(96碩士)，邱鎧澤(96碩士)，謝佳霓(96碩士)，鍾雅雯(96碩士)，林淑燕(96碩士)，陳亮璞(96碩士)，林憲儀(96碩士)，管育平(96碩士)，周郁青(97碩士)，林冠伶(98碩士)，溫世濤(98碩士)，洪玉靜(98碩士)，林耕佑(98碩士)，林巧絜(98碩士)，黃小茹(98碩士)，張喬惠(98碩士)，翁大永(99碩士)，張伊君(99碩士)，駱又瑄(99碩士)，陳奕安(100碩士)，張藝馨(100碩士)，楊宗憲(100碩士)，葉上民(100碩士)，蔡至倫(101碩士)，吳敏翠(101碩士)，孫正岳(101碩士)，林雨寗(101碩士)，蕭文鵑(101碩士)，高兆志(101碩士)，張雯惠(102碩士)，莊家輝(102碩士)，陳律慈(102碩士)，王冠傑(102碩士)，江慧雯(102碩士)，歐陽桓(103碩士)，陳昱璇(103碩士)，李佳紋(104碩士)，吳欣珊(104碩士)，蔡沂瑾(104碩士)，何梅萱(104碩士)，陳香君(105碩士)，黃裕森(105碩士)，楊景程(105碩士)，劉耀文(105碩士)，吳佩穎(106碩士)，林煒峪(106碩士)，張顧議(106碩士)，孫子惠(107碩士)，洪冠妃(107碩士)，李信翰(107碩士)，陳彥廷(107碩士)，陳泰全(107碩士)，蕭凱烜(108碩士)，陳婉如(108碩士)，鄭惟元(108碩士)，柯祈化(108碩士)，賴韻文(109碩士)，蔡忠良(109碩士)，陳盈錚(109碩士)大學部丁昱心、黃嘉洋、陳宥盈、游子朋、楊馨惠、邱珮慈、陳克華歷屆大學部畢業生尤儀德(86)，張瑩徹(87)，張釗綺(87)，翁挺亮(87)，高志豪(87)，周家瑋(87)，林怡君(88)，林玄原(88)，簡嫜憶(88)，沈吉堂(88)，林承岳(88)，周芳俞(89)，王則堯(89)，王育彬(89)，葉凱嘉(90)，蔡東州(90)，鍾銘峻(90)，林崇宇(91)，余秉純(91)，沈志傑(91)，劉妍君(92)，黃彬武(92)，林建宇(92)，梁志嘉(92)，林憲儀(93)，田宜鷺(93)，王毓瑄(93)，章齊軒(94)，朱德威(94)，陳昭順(94)，張伊君(95)，李蕙萍(95)，陳思怡(95)，吳孟容(96)，劉琪玲(96)，游景州(96)，黃怡禎(97)，賴財春(97)，吳紹瑋(98)，王仕名(100)，簡良容(101)，陳瀚乾(101)，湯婷羽(101)，李佩慈(102)，王脩博(102)，張雅筑(103)，甘芳諭(103)，李漢文(103)，白蕙菁(103)，沈秉毅(104)，胡振豪(104)，蔡佳宏(104)，黃浩恩(105)，陳彥廷(105)，林柏諭(105)，李智揚(105)，李妍靚(105)，蔣介皓(106)，林志維(106)，潘慶輔(106)，高永璁(106)，吳依珊(106)，張人允(107)，黃琬庭(107)，劉成展(107)，陳盈錚(108)，莊智捷(108)，郭佶鑫(108)，劉季昀(109)、侯長宏(109)、葉漢中(109)、吳宇軒(109)、羅浚嘉(109)、蒲姿佑(109)現任研究助理陳盈錚、莊慧專歷任研究助理林志成(美國匹茲堡大學醫學院助理研究員)賴怡彣(中興大學生命科學系博士、台中榮民總醫院博士後研究員)楊尚訓(美國EmoryUniversity醫學院博士、成大生理學研究所教授)余佳恆(美商昆泰公司資深臨床研究主任)林怡君(台中生技公司捷恩麥克區經理、南投縣衛生局組員)林建宇(台灣大學分子醫學研究所博士、中研院博士後研究員)劉妍君(台灣大學分子醫學所研究助理)周郁青(尖端臍帶血公司、中化健康生技公司)林冠伶(中研院研究助理)章齊軒(美國BaylorCollegeofMedicine博士)朱德威(美國UniversityofUtah博士)陳新雅(東海大學畜產與生物科技學系研究助理)何梅萱張伊君陳光彥(台灣大學醫學院醫學檢驗暨生物技術學系博士生)魏齊萱(中興大學生命科學院生物醫學研究所博士生)向雨彤TheresaRöhrig(德國籍；MedicalFacultyofMannheimHospital,HeidelbergUniversity)吳欣珊(財團法人生物技術開發中心研究人員)吳佩穎孫子惠楊景程陳淑玲李欣蓓   A.期刊論文  1.G.R.L.Chang,M.Y.Tu,K.Y.Chang,C.F.Chen,J.C.Lai,Y.T.Tung,H.L.Chen,H.C.Fan,andC.M.Chen*2021/10KFP-1,anovelcalcium-bindingpeptideisolatedfromkefir,promotescalciuminfluxthroughTRPV6channels,Mol.Nutr.FoodRes.2021:2100182.[IF=5.914;FoodScience&Technology,9/160=5.6%;Q1](獲選為封面故事CoverStory).(SCI) 2.Y.W.Chiang,S.W.Wu,C.W.Luo,S.P.Chen,C.J.Chen,W.Y.Chen,C.C.Chang,C.M.Chen*,Y.H.Kuan*2021/09Airpollutantparticles,PM2.5,exposureandglaucomainpatientswithdiabetes:Anationalpopulation-basednestedcase–controlstudy,Int.J.Environ.Res.PublicHealth18(18):9939.[IF=3.390;Public,Environmental&OccupationalHealth,41/176=23%;Q1].(SCI) 3.J.L.Wang,Y.T.Tsai,C.H.Lin,A.Cidem,T.Staniczek,G.R.L.Chang,C.C.Yen,W.Chen,K.Y.Chong,andC.M.Chen*2021/08Benefitsofmetformincombinedwithpemetrexedasafirst-linetherapyforadvancedlungadenocarcinomapatientswithdiabetes,Biomolecules11:1252.[IF=4.879;Biochemistry&MolecularBiology,96/298=32.2%;Q2].(SCI) 4.J.L.Wang,Y.W.Lan,Y.T.Tsai,Y.C.Chen,T.Staniczek,Y.A.Tsou,C.C.Yen,C.M.Chen*2021/06Additiveantiproliferativeandantiangiogeniceffectsofmetforminandpemetrexedinanon-small-celllungcancerxenograftmodel,Front.CellDev.Biol.9:688062.doi:10.3389/fcell.2021.688062.[IF=6.684;Oncology,6/41=14.6%;Q1].(SCI) 5.M.Y.Tu,K.Y.Han,Y.W.Lan,K.Y.Chang,C.W.Lai,H.L.Chen,C.F.Chen,J.C.Lai,andC.M.Chen*.2021/06AssociationofTGF-β1andIL-10genepolymorphismswithosteoporosisinastudyofTaiwaneseosteoporoticpatients,Genes12(6):930.(SCI)[IF=4.096;Genetics&Heredity,65/175=37.1%;Q2].(SCI) 6.H.L.Chen,Y.T.Tung,M.Y.Tu,M.N.Y.Chan,H.S.Wu,C.C.Yen,andC.M.Chen*.2021/06Effectsofkefirpeptidesonameliorationofdepressive-likebehaviorthroughBDNF/TrkBpathwayinmice.,J.DairySci.104(6):6415-6430.[IF=4.034;Agriculture,Dairy&AnimalScience,6/63=Top9.5%;Q1].(SCI) 7.Y.W.Lan,C.M.Chen,andK.Y.Chong2021/05InvitromethodstoevaluatetheeffectsofmesenchymalstemcellsonTGF-β1-inducedpulmonaryfibrosis,MethodsMol.Biol.(Clifton,N.J.)2269:83-92.[IF=10.71;MolecularBiology;Q1].(SCI) 8.I.O.Yusuf,H.M.Chen,P.H.Cheng,C.Y.Chang,S.J.Tsai,J.I.Chuang,C.C.Wu,B.M.Huang,H.S.Sun,C.M.ChenandS.H.Yang*2021/05Fibroblastgrowthfactor9stimulatesneuronallengththroughNF-kBsignalinginstriatalcellHuntington’sdiseasemodels,Mol.Neurobiol.58(5):2396-2406.(SCI)[IF=5.590;Physiology,7/81=Top8.6%;Q1].(SCI) 9.C.H.Kuo#,J.Y.Chen#,C.M.Chen#,C.W.Huang,andY.M.Liou*2021/03EffectsofvaryinggelatincoatingconcentrationsonRANKLinducedosteoclastogenesis,Exp.CellRes.400:112509.(SCI)[IF=3.905;Oncology,134/242=55.4%;Q2](#Co-firstauthors).(SCI) 10.F.J.Cheng,C.H.Chen,W.C.Tsai,B.W.Wang,M.C.Yu,T.C.Hsia,Y.L.Wei,Y.C.Hsiao,D.W.Hu,C.Y.Ho,T.S.Li,C.Y.Wu,W.Y.Chou,Y.L.Yu,C.H.Tang,C.Y.Chen,C.M.Chen,...W.C.Hung*.2021/02Cigarettesmoke-inducedLKB1/AMPKpathwaydeficiencyreducesEGFRTKIsensitivityinNSCLC,Oncogene40:1162–1175.(SCI)[IF=9.867;Oncology,30/242=Top12.4%;Q1].(SCI) 11.Y.A.Tsou,W.C.Chang,C.D.Lin,R.L.Chang,M.H.Tsai,L.C.Shih,T.Staniczek,T.F.Wu,H.Y.Hsu,W.D.Chang,C.H.Lai,andC.M.Chen*2021/02Metforminincreasessurvivalinhypopharyngealcancerpatientswithdiabetesmellitus:Retrospectivecohortstudyandcell-basedanalysis,Pharmaceuticals14:191.(SCI)[IF=5.863;Pharmacology&Pharmacy,37/275=Top13.5%;Q1].(SCI) 12.H.Ou-Yang,S.C.Wu,L.Y.Sung,S.H.Yang,S.H.Yang,K.Y.Chong,andC.M.Chen*2021/01STAT3isanupstreamregulatorofgranzymeginthematernal-to-zygotictransitionofmouseembryos,Int.J.Mol.Sci.22:460.(SCI)[IF=5.923;Biochemisrty&MolecularBiology,67/298=22.5%;Q1].(SCI) 13.192. C.M.Chen,Y.-T.Tung,C.-H.Wei,P.-Y.Lee,L.B.Ware,H.-E.Huang,andW.Chen2021Aspirinattenuatedhyperoxiainducedacuterespiratorydistresssyndrome(ARDS)throughsuppressingpulmonaryinflammationviaNF-κBandMAPKssignalingpathway,BMCBiologySubmittedJun.,22.2021.[IF=7.431;Biology,6/112=5.3%;Q1].(SCI) 14.C.F.Chen,H.P.Lee,Y.H.Chao,M.Y.Tu,C.C.Yen,S.H.Yang,C.C.Lin,K.Y.Chong,andC.M.Chen*2021Suppressionofdendriticcellmaturationbykefirpeptidesalleviatescollagen-inducedarthritisinmice,Front.Pharmacol.SubmittedJun.,23.2021.[IF=5.810;Oncology,46/352=13%;Q1].(SCI) 15.L.K.Tsai,H.Ou-Yang,J.Xu,C.M.Chen,W.F.Chang,L.Y.Sung*2021Somaticcellnucleartransferinembryonicdevelopmentandstemcellresearch,Int.J.Mol.Sci.SubmittedJun.,28,2021.(SCI)[IF=5.923;Biochemisrty&MolecularBiology,67/298=22.5%;Q1].(SCI) 16.Y.C.Chen,Y.W.Lan,S.M.Huang,C.C.Yen,W.Chen,W.J.Wu,T.Staniczek,K.Y.Chong,andC.M.Chen*2021Humanamnioticfluidmesenchymalstemcellsattenuatepancreaticcancercellproliferationandtumorgrowthinanorthotopicxenograftmousemodel,CancersSubmittedJun.29,2021.[IF=6.639;oncology,51/242=21%;Q1].(SCI) 17.I.O.Yusuf,H.M.Chen,P.H.Cheng,C.Y.Chang,S.J.Tsai,J.I.Chuang,C.C.Wu,B.M.Huang,H.S.Sun,C.M.ChenandS.H.Yang*2021FGF9inducesneuriteoutgrowthuponERKsignalinginknock-instriatalHuntington'sdiseasecells,LifeSci.267:118952.(SCI)[IF=5.037;LifeScience,7/81=Top8.6%;Q1].(SCI) 18.Y.W.Chiang,S.W.Wu,C.H.Su,H.Y.Sun,C.J.Chen,W.Y.Chen,C.C.Chang,C.M.Chen*2021BisphenolAinducedapoptosisandmitochondrialdysfunctionthroughcaspaseandkeap1/Nrf2pathwayactivationinARPE-19cells,CellBiol.Toxicol.SubmittedJun.,17,2021.[IF=6.691;CellBiology,51/195=26.2%;Q2].(SCI) 19.M.C.Tung,Y.W.Lan,H.H.Li,H.L.Chen,S.Y.Chen,Y.H.Chen,C.C.Lin,M.Y.Tu,andC.M.Chen*.2020Kefirpeptidesalleviatehigh-fatdiet-inducedatherosclerosisbyattenuatingmacrophageaccumulationandoxidativestressinApoEknockoutmice,ScientificReports10:8802.(SCI)[IF=4.379;MultidisciplinarySciences,19/126=Top15%;Q1][Nature系列期刊].(SCI) 20.R.Reisz*,A.LeBlanc,H.Maddin,T.Dudgeon,D.Scott,T.Huang,J.Chen,C.M.Chen,andS.Zhong.2020EarlyJurassicdinosaurfetaldentaldevelopmentanditssignificancefortheevolutionofsauropoddentition,NatureCommunications.11:2240.(SCI)[IF=14.919;MultidisciplinarySciences,5/126=Top3.9%;Q1][Nature系列期刊][Science.Carleton.Ca特別報導;2020/5/7].(SCI) 21.C.M.Chen,Y.T.Tung,C.H.Wei,P.Y.Lee,andW.Chen*.2020Anti-inflammatoryandreactiveoxygenspeciessuppressionthroughaspirinpretreatmenttotreathyperoxia-inducedacutelunginjuryinNF-κB–luciferaseinducibletransgenicmice,Antioxidants9(5):429.(SCI)[IF=6.312;FoodSciences&Technology,11/144=Top7.6%;Q1].(SCI) 22.Y.H.Chen,H.L.Chen,H.C.Fang,Y.T.Tung,C.W.Kuo,M.Y.Tu,andC.M.Chen*.2020Anti-inflammatory,antioxidant,andantifibroticeffectsofkefirpeptidesonsalt-inducedrenalvasculardamageanddysfunctioninagedstroke-pronespontaneouslyhypertensiverats,Antioxidants9(9):790.(SCI)[IF=6.312;FoodSciences&Technology,11/144=Top7.6%;Q1].(SCI) 23.M.Y.Tu,H.Chu,Y.J.Lin,K.T.Chiang,C.M.Chen,C.S.Yang,andC.Y.Lai*.2020Combinedeffectofheartrateresponsesandanti-GstrainingmanoeuvreeffectivenessonGtoleranceinahumancentrifuge,ScientificReports10:21611.(SCI)[IF=4.379;MultidisciplinarySciences,19/126=Top15%;Q1][Nature系列期刊].(SCI) 24.C.M.Chen,H.C.Lu,Y.T.Tung,andW.Chen*.2020Antiplatelettherapyforacuterespiratorydistresssyndrome,Biomedicines8:230.(SCI)[IF=6.081;Pharmacology&Pharmacy,32/275=Top11.6%;Q1].(SCI) 25.M.Y.Tu,K.Y.Han,G.R.L.Chang,G.D.Lai,K.Y.Chang,C.F.Chen,J.C.Lai,C.Y.Lai,H.L.Chen,andC.M.Chen*.2020Kefirpeptidespreventestrogendeficiency-inducedbonelossandmodulatethestructureofthegutmicrobiotainovariectomizedmice,Nutrients12:3432.(SCI)[IF=5.717;Nutrition&Diebetics,17/89=Top19.1%;Q1].(SCI) 26.C.C.Yen,W.H.Chang,M.C.Tung,H.L.Chen,H.C.Liu,C.H.Liao,Y.W.Lan,K.Y.Chong,S.H.Yang,andC.M.Chen*.2020Lactoferrinprotectshyperoxia-inducedlungandkidneysystemicinflammationfrominaninvivoimagingmodelofNF-κB/luciferasetransgenicmice,Mol.ImagingBiol.22(3):526-538.(SCI)[IF=3.488;Radiology,NuclearMedicine&MedicalImaging,35/186=18.8%c;Q1].(SCI) 27.H.L.Chen,K.F.Hung,C.C.Yen,C.H.Laio,J.L.Wang,Y.W.Lan,K.Y.Chong,H.C.Fan,andC.M.Chen*.2019/09Kefirpeptidesalleviateparticulatematter<4μm(PM4.0)-inducedpulmonaryinflammationbyinhibitingtheNF-κBpathwayusingluciferasetransgenicmice,ScientificReports9:11529.(SCI)[IF=5.097;MultidisciplinarySciences,19/126=Top15%;Q1][Nature系列期刊].(SCI) 28.Y.A.Tsou,W.D.Chang,J.J.Lu,T.F.Wu,H.L.Chen,C.M.Chen,andM.H.Tsai*.2019/09Theeffectofmetforminuseonhypopharyngealsquamouscellcarcinomaindiabetesmellituspatients,BMCCancer19:862.(SCI)[IF=4.430;Oncology,121/308=39.3%;Q2].(SCI) 29.T.T.Huang,Y.W.Lan,W.H.C.M.Chen,Y.F.Ko,D.Ojcius,J.Martel,J.YoungandK.Y.Chong*.2019/08Antrodiacinnamomeainducesanti-tumoractivitybyinhibitingtheSTAT3signalingpathwayinlungcancercells,ScientificReports9:5145.[IF=5.097;MultidisciplinarySciences,19/126=Top15%;Q1][Nature系列期刊].(SCI) 30.S.W.Tsai,H.S.Wu,I.A.Chen,H.L.Chen,G.R.L.Chang,H.C.Fan*,andC.M.Chen*.2019/07Amutant-typeporcinemyostatinpropeptide(D75A-MSPP)elevatesmyoblastgrowthanddifferentiationinC2C12cellsandinhighfatdiet-fedmice,Res.Vet.Sci.124:200-211.(SCI)[IF=2.534;VeterinarySciences,20/166=Top12%;Q1].(SCI) 31.H.C.Tsai,G.R.L.Chang,H.C.Fan,H.Ou-Yang,L.C.Huang,S.C.Wu,andC.M.Chen*.2019/06Amini-pigmodelforevaluatingtheefficacyofautologousplateletpatchesoninducedacutefullthicknesswoundhealing,BMCVet.Res.15:191.(SCI)[IF=2.741;VeterinarySciences,16/166=Top9.6%;Q1].(SCI) 32.C.F.Tu,C.K.Chuang,K.S.Hsiao,C.H.Chen,C.M.Chen,S.H.Peng,Y.HSu,M.T.Chiou,C.H.Yen,S.W.Hung,T.S.Yang,andC.M.Chen.2019/05LesseningofporcineepidemicdiarrhoeavirussusceptibilityinpigletsaftereditingoftheCMP-N-glycolylneuraminicacidhydroxylasegenewithCRISPR/Cas9tonullifyN-glycolylneuraminicacidexpression,PLoSONE14(5):0217236.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 33.H.C.Tsai,C.W.Lehman,C.C.Lin,S.W.Tsai,andC.M.Chen*.2019/04FunctionalevaluationforadequacyofMDCK-lineagecellsininfluenzaresearch,BMCRes.Notes12:101.(SCI)IF=1.66.(SCI) 34.Y.W.Lan,J.C.Yang,C.C.Yen,T.T.Huang,Y.C.Chen,H.L.Chen,K.Y.Chong,andC.M.Chen*.2019/01Predifferentiatedamnioticfluidmesenchymalstemcellsenhancelungalveolarepitheliumregenerationandreverseelastase-inducedpulmonaryemphysema,StemCellRes.Ther.10(1):163.(SCI)[IF=6.832;Medicine,Research&Experimental,31/186=Top16.7%;Q1].(SCI) 35.H.C.Tsai,C.W.Lehman,andC.M.Chen*.2019/01Useofplatelet-richplasmaandplatelet-derivedpatchestotreatchronicwounds,J.WoundCare.28(1):15-21.(SCI)[IF=2.072;Dermatology,42/89=47.2%;Q2].(SCI) 36.H.C.Fan,C.M.Chen,C.S.Chi,J.D.Tsai,K.L.Chiang,Y.K.Chang,S.Z.Lin,andH.J.Harn*.2019/01TargetingtelomeraseandATRXtoinducetumorsenescenceandapoptosisinmalignantgliomas,Int.J.Mol.Sci.20(1):200.(SCI)[IF=5.923;Biochemisrty&MolecularBiology,67/298=22.5%;Q1].(SCI) 37.C.C.Kao,H.L.Chen,M.Y.Tu,andC.M.Chen*.2019/01SerumandurinarySOD3inpatientswithtype2diabetes:comparisonwithearlychronickidneydiseasepatientsandassociationwithdevelopmentofdiabeticnephropathy,Am.J.Physiol.RenalPhysiol.316(1):F32-F41.(SCI)[IF=3.377;Urology&Nephrology,25/118=Top21.2%;Q1].(SCI) 38.H.C.Tsai*,H.C.Shu,L.C.Huang,andC.M.Chen*2019Arandomizedclinicaltrialcomparingacollagen-basedcompositedressingversustopicalantibioticointmentonhealingfull-thicknessskinwoundstopromoteepithelialization,FormosanJ.Surgery52:52-56.(SCI)[IF=0.25;Surgery,256/270=94.8%;Q4].(SCI) 39.T.T.Huang,Y.W.Lan,Y.F.Ko,C.M.Chen,H.C.Lai,D.M.Ojcius,J.Martel,J.D.Young,andK.Y.Chong*.2018/09Antrodiacinnamomeaproducesanti-angiogeniceffectsbyinhibitingtheVEGFR2signalingpathway,J.Ethnopharmacol.220:239-249.(SCI)[IF=4.360;Integrative&ComplementaryMedicine,4/39=Top10.2%;Q1].(SCI) 40.Y.T.Wang,H.C.Liu,H.C.Chen,Y.C.Lee,T.C.Tsai,H.L.Chen,H.C.Fan,andC.M.Chen*.2018/07Oralimmunotherapywiththeingestionofhousedustmiteextractinamurinemodelofallergicasthma,AllergyAsthmaClin.Immunol.14:e43.(SCI)[IF=2.104;Allergy,19/27=70.3%;Q3].(SCI) 41.C.Y.Tu,F.J.Cheng,C.M.Chen*,S.L.Wang,Y.C.Hsiao,C.H.Chen,T.C.Hsia,Y.H.He,B.W.Wang,I.S.Hsieh,Y.L.Yeh,C.H.Tang,Y.J.Chen,andW.C.Huang.2018/05Cigarettesmokeenhancesoncogeneaddictiontoc-METanddesensitizesEGFR-expressingnon-smallcelllungcancertoEGFRTKIs,Mol.Oncol.12(5):705-723.(SCI)[IF=6.603;Oncology,38/308=Top12.3%;Q1].(SCI) 42.W.J.Lo,C.L.Lin,Y.C.Chang,L.Y.Bai,C.Y.Lin,J.A.Liang,L.Y.Li,L.M.Chao,C.F.Chiu,C.M.Chen*,andS.P.Yeh.2018/04Totalbodyirradiationtremendouslyimpairtheproliferation,differentiationandchromosomalintegrityofbonemarrow-derivedmesenchymalstromalstemcells,Ann.Hematol.97(4):697-707.(SCI)[IF=3.673;Hematology,40/93=43%;Q2].(SCI) 43.Y.T.Tung,H.L.Chen,H.S.Wu,M.H.Ho,K.Y.Chong,andC.M.Chen*.2018/03Kefirpeptidespreventhyperlipidemiaandobesityinhighfatdiet-inducedobeseratsvialipidmetabolismmodulation,Mol.Nutri.FoodRes.62(3):1700505.(SCI)[IF=5.914;FoodScience&Technology,9/160=Top5.6%;Q1].(SCI) 44.C.Y.Tu†,C.M.Chen†,W.C.Liao,B.R.Wu,C.Y.Chen,W.C.Chen,T.C.Hsia,W.C.Cheng,andC.H.Chen*.2018Comparisonoftheeffectsofthethreemajortyrosinekinaseinhibitorsasfirst-linetherapyfornon-small-celllungcancerharboringepidermalgrowthfactorreceptormutations,Oncotarget.9(36):24237-24247.(SCI)[5-yIF=5.168;Oncology,44/217=Top20.3%;Q1]†Co-firstauthor..(SCI) 45.C.Y.Tu,B.W.Wang,F.J.Cheng,C.H.Chen,T.C.Hsia,Y.L.Wei,C.Y.Chen,I.S.Hsieh,Y.L.Yeh,L.Y.Wang,C.M.Chen,W.C.ChangandW.C.Chang*.2018IncenseburningsmokesensitizeslungcancercellstoEGFRTKIbyinducingAREGexpression,Am.J.CancerRes.8(12):2575-2589.(SCI)[IF=6.166;Oncology,70/308=22.7%;Q1].(SCI) 46.Y.A.Tsou,M.C.Tung,K.A.Alexander,W.D.Chang,M.H.Tsai,H.L.Chen,andC.M.Chen*.2018TheroleofBPIFA1inupperairwaymicrobialinfectionsandcorrelateddiseases,BioMed.Res.Int.2018:e2021890.(SCI)[IF=3.411;Biotechnology&AppliedMicrobiology,69/159=43.4%;Q2].(SCI) 47.C.M.Chen*,J.L.Wang,Y.T.Tsai,J.H.Jiang,andH.L.Chen.2017/09Repurposingofmetforminandlungcancermanagement.In:AGlobalScientificVision-Prevention,Diagnosis,andTreatmentofLungCance,InTechPublishers,Inc.Rijeka,EU.Chapter9,pp.149-163.ISBN978-953-51-5119-7.. 48.L.S.Her,S.H.Mao,C.Y.Chang,P.H.Cheng,H.I.Yang,C.M.ChenandS.H.Yang*.2017/09miR-196aenhancesneuronalmorphologythroughsuppressingRANBP10toprovideneuroprotectioninHuntington'sdisease,Theranostics.7(9):2452-2462.(SCI)[IF=11.556;Medicine,Research&Experimental,6/186=Top3.2%;Q1].(SCI) 49.Y.W.Lan,S.M.Theng,T.T.Huang,K.B.Choo,C.M.Chen,H.P.Kuo,andK.Y.Chong*.2017/08OncostatinM-preconditionedmesenchymalstemcellsalleviatebleomycin-inducedpulmonaryfibrosisthroughparacrineeffectsofthehepatocytegrowthfactor,StemCellsTranslat.Med.6(3):1006-1017.(SCI)[IF=6.940;Cell&TissueEngineering,4/31=12.9%;Q1].(SCI) 50.C.W.Lai,H.L.Chen,K.Y.Chong,W.Y.Lin,andC.M.Chen*.2017/05AnovelosteoporosismodelwithascorbicaciddeficiencyinAkr1A1geneknockoutmice,Oncotarget.8(5):7357-7369.(SCI)[IF=5.168;Oncology,44/217=Top20.3%;Q1].(SCI) 51.Y.A.Tsou,Y.T.Tung,H.C.Chen,T.F.Wu,C.C.Lin,C.H.Lai,H.L.Chen,andC.M.Chen*.2017/03LactoferrininteractswithSPLUNC1toattenuatelipopolysaccharide-inducedinflammationofhumannasalepithelialcellsviadown-regulatedMEK1/2-MAPKsignaling,Biochem.CellBiol.95(3):394-399.[IF=3.626;Biochemistry&MolecularBiology,168/298=56.4%;Q3](SCI).(SCI) 52.J.Y.Hsu,Y.L.Jhang,P.H.Cheng,Y.F.Chang,S.H.Mao,H.I.Yang,C.W.Lin,C.M.ChenandS.H.Yang*.2017ThetruncatedC-terminalfragmentofmutantATXN3disruptsmitochondriadynamicsinSpinocerebellarataxiatype3models,Front.Mol.Neurosci.10:196.eCollection2017.(SCI)[IF=5.639;Neurosciences,60/273=Top21.9%;Q1].(SCI) 53.P.H.Cheng,Y.F.Chang,S.H.Mao,H.L.Lin,C.M.Chen,andS.H.Yang*.2016/08Lentiviraltransgenesisinmiceviaasimplemethodofviralconcentration,Theriogenology86(6):1427-1435.(SCI)[IF=2.740;VeterinarySciences,22/166=Top13.3%;Q1].(SCI) 54.C.W.Lai,H.L.Chen,T.C.Tsai,T.W.Chu,S.H.Yang,K.Y.Chong,andC.M.Chen*.2016/08SexuallydimorphicexpressionofeGFPtransgeneintheAkr1A1locusofmouseliverregulatedbysexhormone-relatedepigeneticremodeling,ScientificReports6:e24023.[IF=4.379;MultidisciplinarySciences,19/126=Top15%;Q1][Nature系列期刊].(SCI) 55.C.W.Lai,H.L.Chen,C.C.Yen,J.L.Wang,S.H.Yang,andC.M.Chen*.2016/06Usingdual-fluorescencereportinggenestoestablishaninvivoimagingmodeloforthotopiclungadenocarcinomainmice,Mol.ImagingBiol.18(6):849-859.[IF=3.488;Radiology,NuclearMedicine&MedicalImaging,35/186=18.8%;Q1].(SCI) 56.W.J.Lo,W.S.Chang,H.F.Hsu,H.X.Ji,C.L.Hsiao,C.W.Tsai,S.P.Yeh,C.M.Chen*andD.T.Bau*.2016/05Significantassociationofinterleukin-10polymorphismswithchildhoodleukemiasusceptibilityinTaiwan,InVivo30(3):265-269.(SCI)[Medicne,Research&Experimental].(SCI) 57.S.W.Tsai,H.L.Chen,Y.T.Tung,S.H.Yang,C.Y.Liu,M.Lu,H.J.Pai,C.C.Lin,andC.M.Chen*.2016/01Myostatinpropeptidegenedeliverybygenegunamelioratesmuscleatrophyinaratmodelofbotulinumtoxin-inducednervedenervation,LifeSci.146:15-23.(SCI)[IF=5.037;LifeScience,35/186=Top2.7%;Q1].(SCI) 58.H.L.Chen,T.C.Tsai,Y.C.Tsai,J.W.Liao,C.C.Yen,andC.M.Chen*.2016Kefirpeptidespreventhigh-fructosecornsyrup-inducednon-alcoholicfattyliverdiseaseinamurinemodelbymodulationofinflammationandtheJAK2signalingpathway,Nutrition&Diabetes6(12):e237.(SCI)[IF=5.097;InternalMedicine,21/146=15.4%;Q1][Nature系列期刊].(SCI) 59.W.Chen,Y.Y.Chen,C.F.Tsai,S.C.C.Chen,M.S.Lin,L.B.Ware,andC.M.Chen*.2015/09Incidenceandoutcomesofacuterespiratorydistresssyndrome–AnationwideregistrybasedstudyinTaiwan,1997-2011,Medicine94(43):e1849.[IF=1.889;Medicine,General&Internal,105/313=Top33.5%;Q2].(SCI) 60.M.H.Fu,C.L.Li,H.L.Lin,S.J.Tsai,Y.Y.Lai,Y.F.Chang,P.H.Cheng,C.M.Chen,andS.H.Yang*.2015/09ThepotentialregulatorymechanismsofmiR-196ainHuntington'sdiseasethroughbioinformaticanalyses,PLoSONE10(9):e0137637.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 61.C.Y.Liu,M.L.Lee,C.S.Yang,C.M.Chen,M.Y.Min,andH.W.Yang*.2015/08MorphologicalandphysiologicalevidenceofasynapticconnectionbetweenthelateralparabrachialnucleusandneuronsintheA7catecholaminecellgroupinrats,J.Biomed.Sci.,22(1):79.[IF=8.410;Medicine,General&Internal,38/195=19.5%;Q1].(SCI) 62.Y.W.Lan,K.B.Choo,C.M.Chen,T.H.Hung,Y.B.Chen,C.H.Hsieh,H.P.Kuo,andK.Y.Chong*.2015/06Hypoxia-preconditionedmesenchymalstemcellsattenuatesbleomycin-inducedpulmonaryfibrosis,StemCellRes.Ther.6(1):97.(SCI)[IF=4.963;Medicine,Research&Experimental,19/133=Top14.3%;Q1](HighlyAccessPaper:2063times)[CellResearch&Therapy6:130,2015特別報導;07/14/2015].(SCI) 63.C.W.Kuo,C.J.Shen,Y.T.Tung,H.L.Chen,Y.H.Chen,W.H.Chang,K.C.Cheng,S.H.Yang,andC.M.Chen*.2015/06Extracellularsuperoxidedismutaseamelioratesstreptozotocin-induceddiabeticnephropathyviainhibitingtheROS/ERK1/2signaling,LifeSci.135:77-86.(SCI)[IF=5.037;Medicine,Research&Experimental,35/186=18.8%;Q1].(SCI) 64.Y.A.Tsou,C.D.Lin,H.H.Hsu,M.T.Peng,Y.K.Kuo,N.Tien,J.P.Li,C.K.Wang,H.S.Wu,M.H.Tsai,C.M.Chen*andC.H.Lai.2015/06Associationofbeta-lactam-sensitiveHaemophilusinfluenzaetypeBwithadenoidbiofilmformationinpatientswithadenoidectomysurgery,Surg.Infect.16(6):709-715.(SCI)[IF=2.150;Surgery120/270=44.4%;Q2][FeatureArticles特別報導;12/08-22/2015].(SCI) 65.Y.T.Tung,P.W.Huang,Y.C.Chou,C.W.Lai,H.P.Wang,H.C.Ho,C.C.Yen,C.Y.Tu,D.C.Yeh,J.L.Wang,K.Y.Chong,andC.M.Chen*2015/05Lungtumorigenesisinducedbyhumanvascularendothelialgrowthfactor(hVEGF)-A165overexpressionintransgenicmiceandameliorationoftumorformationbymiR-16,Oncotarget.6(12):10222-10238.(SCI)[IF=5.168;Oncology,44/217=Top20.3%;Q1].(SCI) 66.T.C.Tsai,Y.T.Tung,Y.H.Kuo,J.W.Liao,H.C.Tsai,K.Y.Chong,H.L.Chen,andC.M.Chen*2015/02Anti-inflammatoryeffectsofAntrodiacamphorata,anherbalmedicine,inamouseskinischemiamodel,J.Ethnopharmacol.159:113-121.(SCI)[IF=4.360,Integrative&complementarymedicine,4/39=Top10.2%;Q1].(SCI) 67.K.Y.Chong,C.J.Hsu,T.H.Hung,H.S.Hu,T.H.Wang,C.H.Wang,C.M.Chen,K.B.Choo,H.C.Lai,andC.P.Tseng.2015/01WntpathwayactivationandABCB1expressionaccountforattenuationofproteasomeinhibitor-mediatedapoptosisinmultidrug-resistantcancercells,CancerBiolTher.16(1):149-159.(SCI)[IF=4.742,Oncology,102/308=33.1%;Q2].(SCI) 68.H.C.Liu,M.C.Lu,Y.C.Lin,Y.C.Lai,M.S.Jan,W.L.Lin,andC.M.Chen*2015/01Aorticgraftinfectioncausedbyinvasivepulmonaryaspergillosis,Surg.Infect.16(1):112-113.(SCI)[IF=2.150;Surgical,120/270=44.4%;Q2].(SCI) 69.H.L.Chen,Y.T.Tung,C.H.Chuang,M.Y.Tu,T.C.Tsai,S.Y.Chang,andC.M.Chen*2015/01Kefirimprovesbonemassandmicroarchitectureinanovariectomizedratmodelofpostmenopausalosteoporosis,OsteoporosisInt.26:589-599.(SCI)[IF=4.507;Endocrinology&Metabolism,47/177=26.6%;Q2][WorldBiomedicalFrontiers特別報導;09/28/2015].(SCI) 70.H.C.Liu,H.L.Chen,andC.M.Chen*.2015/01Housedustmiteallergyandassociatedallergen-specificimmunotherapyinallergicasthma,ImmunomeRes.11:085.(SCI)[UnofficialIF*=19.87;Immunology].(SCI) 71.Y.A.Tsou,C.C.Lin,C.J.Tai,M.H.Tsai,C.M.Chen*,andC.H.Lai*.2015Interleukin-13inhibitslipopolysaccharide-inducedBPIFA1expressioninnasalepithelialcells,PLoSONE10(12):e0143484.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 72.M.Y.Tu,H.L.Chen,Y.T.Tung,T.C.Tsai,S.Y.Chang,C.H.Chuang,andC.M.Chen*.2015Short-termeffectsofkefir-fermentedmilkconsumptiononbonemineraldensityandbonemetabolisminarandomizedclinicaltrialofosteoporoticpatients,PLoSONE10(12):e0144231.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 73.Y.L.Lin,H.L.Chen,S.B.Cheng,D.C.Yeh,C.C.Huang,F.K.P’eng,T.C.Tsai,C.C.WuandC.M.Chen*.2015Methylation-silencingRCC1expressionisassociatedwithtumorigenesisanddepthofinvasioningastriccancer,Int.J.Clin.Exp.Pathol.8(11):14257-14269.(SCI)[IF=1.706;Oncology,280/308=90.9%;Q4].(SCI) 74.T.H.Hung,Y.H.Li,C.P.Tseng,Y.W.Lan,S.C.Hsu,Y.H.Chen,T.T.Huang,H.C.Lai,C.M.Chen,K.B.Choo,andK.Y.Chong2015Knockdownofc-METinducedapoptosisinABCB1-overexpressedmultidrug-resistancecancercelllines,CancerGeneTher.22(5):262-270.(SCI)[IF=5.987,Medcine,Research&Experimental,33/186=17.7%;Q1].(SCI) 75.H.L.Chen,Y.T.Tung,C.L.Tsai,C.W.Lai,H.C.Tsai,Y.L.Lin,C.H.Wang,andC.M.Chen2014/09Kefirimprovesfattyliversyndromethroughinhibitedlipogenesispathwayinleptin-deficientob/obknockoutmice,Int.J.Obesity38(9):1172-1179.(SCI)[IF=5.095;Nutrition&Dietetics,15/103=Top14.6%;Q1][Nature系列期刊].(SCI) 76.T.H.Hung,C.M.Chen,C.P.Tseng,C.J.Shen,H.L.Wang,K.B.Choo,andK.Y.Chong2014/08FZD1activatesproteinkinaseCdelta-mediateddrug-resistanceinmultidrug-resistantMES-SA/Dx5cancercells,Int.J.Biochem.CellBiol.53:55-65.(SCI)[IF=5.085;Biochemistry&MolecularBiology88/298=29.5%;Q2].(SCI) 77.H.C.Liu,S.Y.Pai,H.L.Chen,C.W.Lai,T.C.Tsai,W.T.K.Cheng,S.H.Yang,andC.M.Chen*2014/07RecombinantDerp5secretedinthemilkleadingbyaS1-caseinsignalpeptideprotectsagainstdustmiteallergen-inducedairwayinflammation,J.DairySci.97:6792-6803.(SCI)[IF=4.034;Agriculture,Dairy&AnimalScience,6/63=Top9.5%].(SCI) 78.Y.T.Tung,T.Y.Tang,H.L.Chen,S.H.Yang,K.Y.Chong,andC.M.Chen2014/06Lactoferrinprotectsagainstchemical-inducedratliverfibrosisthroughinhibitingstellatecellsactivation,J.DairySci.97(6):3281-3291.(SCI)[IF=4.034;Agriculture,Dairy&AnimalScience,6/63=Top9.5%;Q1].(SCI) 79.C.C.Lin*,H.H.Chen,Y.K.Chen,H.C.Chang,P.Y.Lin,I.H.Pan,D.Y.Chen,C.M.Chen,andS.Y.Lin2014/06Ricebranferuloylatedoligosaccharidesactivatedendriticcellsviatoll-likereceptor2and4signaling,Molecules19:5325-5347.(SCI)[IF=4.411;Biotechnology&AppliedMicrobiology,69/159=38.9%;Q2].(SCI) 80.R.H.Lin,C.C.Huang,Y.A.Tsou*,C.D.Lin,M.H.Tsai,J.H.Chen,C.M.Chen*andY.T.Shiao2014/06Correlationbetweenimagingcharacteristicsandmicrobiologyinpatientswithdeepneckinfections:Aretrospectivereviewofonehundredsixty-onecases,Surg.Infect.15(6):794-799.(SCI)[IF=2.150;Surgery120/270=44.4%;Q2].(SCI) 81.Z.L.Lai,Y.A.Tsou,S.R.Fan,M.H.Tsai,H.L.Chen,J.C.Cheng,andC.M.Chen*2014/06Methylation-associatedgenesilencingofRARBinArecaarcinogens-inducedmouseoralsquamouscellcarcinoma,BioMed.Res.Int.2014:e378358.(SCI)[IF=3.411;Biotechnology&AppliedMicrobiology,69/159=43.4%;Q2].(SCI) 82.Y.J.Chen,M.S.Lin,K.Y.Hsu,C.R.Chen,C.M.Chen,andW.Chen2014/05PrevalenceofasymptomaticperipheralarterialdiseaseandrelatedriskfactorsinyoungerandelderlypatientsinTaiwan,Angiology65(5):396-401.(SCI)[IF=3.619;PeripheralVascularDisease,25/65=38.5%;Q2].(SCI) 83.Y.A.Tsou,C.C.Lin,C.J.Tai,M.H.Tsai,T.C.Tsai,andC.M.Chen2014/04ChronicrhinosinusitisandtheriskofnasopharyngealcancerinaTaiwanesehealthstudy,Am.J.Rhinol.Allergy28(4):168-172.(SCI).[IF=2.467;Otorhinolaryngology11/58=19%;Q1][MDLinx特別報導;07/28/2014].(SCI) 84.H.L.Chen,C.C.Yen,S.M.Wang,T.C.Tsai,Z.L.Lai,J.Y.Sun,W.Lin,W.H.Hsu,andC.M.Chen2014/03Aerosolizedbovinelactoferrinreduceslunginjuryandfibrosisinmiceexposedtohyperoxia,BioMetals27:1057-1068.(SCI)[IF=2.949;Biochemistry&MolecularBiology201/298=67.4%;Q3].(SCI) 85.C.W.Lai,H.L.Chen,K.Y.Lin,F.C.Liu,K.Y.Chong,W.T.K.Cheng,andC.M.Chen2014/03FTSJ2,aheatshock-induciblemitochondrialprotein,suppressescellinvasionandmigration,PLoSONE9(3):e90818.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 86.Y.A.Tsou,M.T.Peng,Y.F.Wu,C.H.Lai,C.D.Lin,C.J.Tai,M.H.Tsai,C.M.Chen*,andH.C.Chen2014/02DecreasedPLUNCexpressioninnasalpolypsisassociatedwithmultibacterialcolonizationinchronicrhinosinusitispatients,Eur.Arch.Otorhinolaryngol.271(2):299-304.(SCI)[IF=2.503;Otorhinolaryngology,14/58=24.1%;Q1][LeadingNews特別報導;05/07/2013].(SCI) 87.L.Y.Sung,W.F.Chang,QZhang,C.C.Liu,C.C.Chang,H.Fu,J.Y.Liou,W.T.K.Cheng,M.Okuka,D.L.Keefe,Y.E.Chen,L.Liu,C.M.Chen,andJ.Xu*2014Telomereelongationandnaïvepluripotentstemcellsachievedfromtelomerasehaplo-insufficientcellsbysomaticcellnucleartransfer,CellReports.9:1603-1609.(SCI)[IF=9.423;CellBiology,28/196=Top14.3%;Q1].(SCI) 88.Y.W.Lan,K.B.Choo,C.M.Chen,T.H.Hung,C.H.Hsieh,H.P.Kuo,andK.Y.Chong*2014Wnt5AregulatesABCB1expressioninmultidrug-resistantcancercellsthroughactivationofthenon-canonicalPKA/β-cateninpathway,Oncotarget.5(23):12273-12290.(SCI)[5-yIF=5.168;Oncology,44/217=Top20.3%;Q1].(SCI) 89.Y.T.Tung,T.C.Tsai,Y.H.Kuo,H.L.Chen,C.C.Yen,J.Y.Sun,W.H.Chang,H.L.Chen,andC.M.Chen*2014Comparisonofsolid-state-culturedandwood-culturedAntrodiacamphoratainanti-inflammatoryeffectsusingNF-κB/luciferaseinducibletransgenicmice,Phytomedicine21(2014):1708-1716.[IF=5.340,Integrative&complementarymedicine,2/39=Top5.1%;Q1].(SCI) 90.H.C.Liu,M.C.Lu,Y.C.Lin,T.C.Wu,J.Y.Hsu,M.S.Jan,andC.M.Chen*2014DifferencesinIL-8inserumandexhaledbreathcondensatefrompatientswithexacerbatedCOPDorasthmaattacks,J.Formos.Med.Assoc.113:908-914.(SCI)[IF=3.282,Medicine,General&Internal,40/313=12.8;Q1].(SCI) 91.Y.A.Tsou,H.J.Huang,T.C.Wang,C.M.Chen*,andC.Y.Chen*2014EvaluationofcorrelationofcellcycleproteinsandKi67interactioninparanasalsinusinvertedpapillomaprognosisandsquamouscellcarcinomatransformation,BioMed.Res.Int.2014:e634945.(SCI)[IF=3.411;Biotechnology&AppliedMicrobiology,69/159=43.4%;Q2].(SCI) 92.C.J.Shen,Y.A.Tsou,S.C.Wu,W.T.K.Cheng,H.L.Chen,C.Y.C.Chen,andC.M.Chen*2014OsteoponinpromotercontrolledbyDNAmethylation:Aberrantmethylationinclonedporcinegenome,BioMed.Res.Int.2014:e327538.(SCI)[IF=3.411;Biochemistry&MolecularBiology,116/298=43.4%;Q2].(SCI) 93.J.T.Huang,C.P.Tseng,M.H.Liao,C.H.Lu,W.Z.Yeh,N.Sakamoto,C.M.Chen*,andJ.C.Cheng.2013/09HepatitisCvirusreplicationismodulatedbytheinteractionofnon-structuralproteinNS5Bandfattyacidsynthase,J.Virol.87(9):4994-5004.(SCI)[IF=5.103;Virology,6/36=16.7%;Q1][SciBite:Pharma特別報導;02/26/2013].(SCI) 94.W.Chen,J.Y.Chen,H.L.Chen,Y.T.Tung,C.W.Kuo,F.C.Mao,C.H.Chuang,K.Y.Chong,andC.M.Chen*2013/09High-frequencyultrasoundimagingtoevaluateliverfibrosisprogressioninratsandYiGuanJianherbaltherapeuticeffects,Evid.Complement.Alter.Med.2013:e302325.(SCI)[IF=2.629,Integrative&complementarymedicine,12/29=41.4%;Q2].(SCI) 95.91. S.T.Wen,W.Chen,H.L.Chen,C.W.Lai,C.C.Yen,K.H.Lee,andC.M.Chen*2013/09AmnioticfluidstemcellsfromEGFPtransgenicmiceattenuatehyperoxia-inducedacutelunginjury,PLoSONE8(9):e75383.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 96.S.W.Tsai,Y.T.Tung,H.L.Chen,C.J.Shen,C.H.Chuang,T.Y.Tang,andC.M.Chen*2013/08TreadmillrunningupregulatestheexpressionofacetylcholinereceptorinratgastrocnemiusfollowingBotulinumToxinAinjection,J.OrthopRes.31:125–131.(SCI)[IF=3.494;Orthopedics,14/117=Top12%;Q1][Science.gov特別報導;03/15/2013].(SCI) 97.Y.T.Tung,H.L.Chen,C.Y.Lee,Y.C.Chou,P.Y.Lee,H.C.Tsai,C.C.Yen,Y.L.Lin,andC.M.Chen*.2013/07ActivecomponentofDanshen(SalviamiltiorrhizaBunge),TanshinoneI,attenuateslungtumorigenesisviainhibitionsofVEGF,CyclinAandCyclinBexpression,Evid.Complement.Alter.Med.2013:e319247.[IF=2.629,Integrative&complementarymedicine,12/29=41.4%;Q2].(SCI) 98.Y.T.Tung,H.L.Chen,H.C.Tsai,S.H.Yang,Y.C.Chang,andC.M.Chen*2013/07TherapeuticpotentialofandrographolideisolatedfromtheleavesofAndrographispaniculataNeesfortreatinglungadenocarcinomas,Evid.Complement.Alter.Med.2013:e305898.[IF=2.629,Integrative&complementarymedicine,12/29=41.4%;Q2].(SCI) 99.C.M.Chen*,Z.L.Lai,M.L.Wang,andH.L.Chen2013/06Cloningandexpressionofhumanextracellularsuperoxidedismutase(EC-SOD)geneinprobioticLactobacilluscasei,Int.J.Biosci.Biochem.Bioinform.3(6):557-561.(SCI).(SCI) 100.H.L.Chen,T.C.Tsai,J.C.Huang,D.C.Wang,andC.M.Chen*2013/06Dimorphicgoatamelogeninallelesonsexchromosomesforgenderdeterminationofpreimplantationembryos,Int.J.Biosci.Biochem.Bioinform.3(6):619-623.(SCI).(SCI) 101.Y.A.Tsou,C.C.Lin,C.H.Lai,C.Y.Wang,C.D.Lin,P.C.Chen,I.J.Tsai,C.M.Chen,F.C.Sung*,andM.H.Tsai2013/05DoesAdenotonsillectomyreallyreducedclinicvisitsforpediatricupperrespiratorytractinfections?AnationaldatabasestudyinTaiwan,Int.J.Pediatr.Otorhinolaryngol.77(5):677-681.(SCI)[IF=1.675;Otorhino-laryngology,28/58=48.3%;Q2].(SCI) 102.C.J.Shen,C.C.Lin,P.C.Shen,W.T.K.Cheng,H.L.Chen,T.C.Chang,S.S.Liu,andC.M.Chen*2013/05Imprintedgenesandsatellitearedifferentiallymethylatedlociinclonedbovinegenomes,CellReprogram.15(5):413-24.(SCI)[IF=1.987;Genetics&Heredity,139/183=76%;Q4][BioPortfolio:TheWorld'sLeadingBiotech,HealthcareandMedicalResource特別報導;11/08/2013].(SCI) 103.M.S.Lin,K.Y.Hsu,Y.J.Chen,C.R.Chen,C.M.Chen,andW.Chen*2013/05PrevalenceandriskfactorsofasymptomaticperipheralarterialdiseaseinpatientswithCOPDinTaiwan,PLoSONE8(5):e64714.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 104.Y.T.Tung,C.C.Yen,H.L.Chen,P.Y.Lee,H.C.Tsai,M.F.Lin,andC.M.Chen*.2013/04BovinelactoferrininhibitslungcancergrowththroughsuppressionofinflammationandVEGFexpression,J.DairySci.96(4):2095-2106.(SCI)[IF=4.034;Agriculture,Dairy&AnimalScience,6/63=Top9.5%;Q1][CancerCommons:Angiogenesis特別報導;02/22/2013](HiCiPaper;8/17/2015).(SCI) 105.Y.A.Tsou#,C.M.Chen#,T.C.Lin,F.W.Hu,C.J.Tai,H.C.Chen,T.H.Yeh,H.J.Harn,M.H.Tsai,andC.I.Jan*2013/04DecreasedSplunc-1expressionisassociatedwithPseudomonasinfectioninsurgicaltreatedchronicrhinosinusitispatientswhomayrequirerepeatedsinussurgery,Laryngoscope123(4):845-851.(SCI)[IF=3.325;Otorhinolaryngology,9/44=20.4%;Q1]†Co-firstauthor.(SCI) 106.P.H.Cheng,C.L.Li,S.J.Tsai,Y.Y.Lai,A.W.S.Chan,C.M.Chen,andS.H.Yang*2013/02MiR-196aamelioratesphenotypesofHuntington'sdiseaseincell,transgenicmouseandindividual-derivedinducedpluripotentstemcellmodels.,Am.J.Hum.Genet.93(2):306-312.(SCI)[IF=11.025;Genetics&Heredity,5/183=Top2.7%;Q1].(SCI) 107.H.C.Liu,S.Y.Pai,W.T.K.Cheng,H.L.Chen,T.C.Tsai,S.H.Yang,andC.M.Chen*2013/01IngestionoftransgenicanimalmilkscontainingtheDp2peptide,adustmiteallergen,potentiallyprotectsmicefromallergicairwayinflammationandhyper-responsiveness,AllergyAsthmaClin.Immunol.9(1):e21.(SCI)[IF=3.406;Allergy,21/37=Top56.8%;Q3][OtoRhinoLaryngology特別報導;07/23/2013].(SCI) 108.P.H.Cheng,C.L.Li,L.S.Her,Y.F.Chang,A.W.S.Chan,C.M.Chen,andS.H.Yang.2013/01SignificantlydifferentialdiffusionofneuropathologicalaggregatesinthebrainoftransgenicmicecarryingN-terminalmutanthuntingtinfusedwithgreenfluorescentprotein,BrainStruct.Funct.218(1):283-94.(SCI)[IF=3.270;Anatomy&Morphology,1/23=Top4.3%;Q1][SciBiteNews特別報導;04/03/2012].(SCI) 109.S.W.Tsai,H.L.Chen,Y.C.Chang,andC.M.Chen*2013MolecularMechanismsoftreadmilltherapyonneuromusclaratrophyinducedviabotulinumtoxinA,NeuralPlasticity.2013:e593271.(SCI)[IF=3.599,Neurosciences,138/273=50.5%;Q3].(SCI) 110.H.Y.Chen,C.J.Chen,Y.N.Lin,Y.H.Chen,W.C.Chen,andC.M.Chen2013Proteomicanalysisrelatedtostressurinaryincontinencefollowingvaginaltraumainfemalemice,Eur.J.Obstet.Gynecol.Reprod.Biol.171(2013):171-179.(SCI)[IF=2.435,Obstetrics&Gynecology,60/121=49.6%;Q2].(SCI) 111.Y.T.Wang,S.Y.Chang,Y.C.Huang,T.C.Tsai,C.M.Chen,andC.T.Lim2013Nanomechanicsinsightsintotheperformanceofhealthyandosteoporoticbones,NanoLett.13(11):5247-5254.[IF=13.025;Nanoscience&Nanotechnology,4/69=Top5.8%][NanowerkNews特別報導;10/10/2013].(SCI) 112.Y.C.Lin,M.C.Lu,C.Lin,M.K.Chiang,M.S.Jan,H.L.Tang,H.C.Liu,W.L.Lin,C.Y.Huang,C.M.Chen*andY.C.Lai2013ActivationofIFN-r/STAT/IRF-1inhepaticresponsestoKlebsiellapneumoniaeinfection,PLoSONE8(11):e79961.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 113.W.C.Chen,K.D.Tsai,C.H.Chen,M.S.Lin,C.M.Chen,C.M.Shih,andW.Chen*2012/09RoleofGallium-67scintigraphyintheevaluationofoccultsepsisinthemedicalICU,Intern.Emerg.Med.7:53-58.(SCI)[IF=3.397;Medicine,General&Internal,55/313=17.6%;Q1].(SCI) 114.J.Y.Chen,H.L.Chen,J.C.Cheng,H.J.Lin,Y.T.Tung,C.F.Lin,andC.M.Chen*2012/06AChineseherbalmedicine,Gexia-ZhuyuTang(GZT),preventsdimethylnitrosamine-inducedliverfibrosisthroughinhibitionofhepaticstellatecellsproliferation,J.Ethnopharmacol.142:811-818.[IF=4.360,Integrative&ComplementaryMedicine,4/39=10.3%;Q1].(SCI) 115.J.C.Lai,M.Y.Tu*,C.M.Chen,andF.Y.Wang2012/03Spinalepiduralabscessinthelumbarspineafterdentalextractionina53-year-oldman,Formos.J.Musculoskel.Disor.3:144-147.(SCI). 116.C.J.Shen,W.T.K.Cheng,S.C.Wu,H.L.Chen,T.C.Tsai,S.H.Yang,andC.M.Chen*2012/02Differentialdifferencesinmethylationstatusofputativeimprintedgenesamongclonedswinegenomes,PLoSONE7(2):e32812.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 117.S.W.Tsai,C.J.Chen,H.L.Chen,C.M.Chen*andY.Y.Chang2012/02TheeffectsoftreadmillrunningonratgastrocnemiusfunctionfollowingbotulinumtoxinAinjection,J.OrthopRes.30(2):319-324.(SCI)[IF=3.494;Orthopedics,9/63=Top12%;Q1].(SCI) 118.M.C.Chen,C.Y.Huang,S.L.Hsu,E.Lin,C.T.Ku,H.Lin*,andC.M.Chen*2012RetinoicacidinducesapoptosisofprostatecancerDU145cellsthroughCdk5over-activation,Evid.Complement.Alter.Med.[IF=2.629,Integrative&complementarymedicine,12/29=41.4%;Q2].(SCI) 119.S.W.Tsai,H.L.Chen,andC.M.Chen*2012Theeffectsoftreadmillonmuscleactivityandneuromuscularjunctionofbotulinumtoxin-inducedmuscleatrophy,NovaSciencePublishers,Inc.NewYork,USA.pp.1-8..pp.1-8. 120.J.Y.Chen,H.L.Chen,S.H.Wu,T.C.Tsai,M.F.Lin,C.C.Yen,W.H.Hsu,W.Chen,andC.M.Chen*2012Applicationofhigh-frequencyultrasoundforthedetectionofsurgicalanatomyintherodentabdomen,Vet.J.191:246-252.(SCI).[IF=2.688;VeterinarySciences,26/166=Top15.7%;Q1].pp.246-252.(SCI) 121.78. Y.J.Chen,Y.T.Chang,J.L.Shen,T.T.Chen,C.B.Wang,C.M.Chen,andC.Y.Wu*2012Associationbetweensystemicantipsoriaticdrugsandcardiovascularriskinpatientswithpsoriasiswithorwithoutpsoriaticarthritis:anationwidecohortstudy,Arthritis&Rheumatism64(6):1879-1887.(SCI)[IF=7.379,Rheumatology1/22=Top4.5%;Q1]DOI10.1002/art.34335.(SCI) 122.C.C.Yen,H.L.Chen,andC.M.Chen*2011Lactoferrin–anovelnaturalhostdefenseprotectagainstEscherichiacoliinfection.In:M.C.RogersandN.D.Peterson,E.coliinfections:Causes,TreatmentandProtection,NovaSciencePublishers,Inc.NewYork,USA.pp.113-124.. 123.K.T.Ho,Y.H.Chang,S.H.Lu,C.N.Huang,C.M.Chen,andM.Y.Shiau*2011Regulationofglucose/lipidmetabolismandinsulinsensitivitybyinterleukin-4,Int.J.Obesty[IF=5.095;Nutrition&Dietetics,15/103=Top14.6%;Q1](SCI)(Accepted)..(SCI) 124.M.C.Chen,C.M.Chen*,andH.Lin*2011Cyclin-dependentkinase5regulatesandrogenproductioninmouseovarythecalcells,Biol.Reprod.85:708.(SCI)[IF=4.285;ReproductiveBiology,5/30=Top16.7%;Q1].(SCI) 125.C.M.Hung,C.C.Yeh,K.Y.Chong,H.L.Chen,S.T.Kao,C.C.Yen,M.H.Yeh,M.S.Lin,andC.M.Chen*2011Gingyo-SanenhancesperipherallymphocyteproliferationandassistsinfectiousBursaldiseasevaccinationinnativechicken,Evid.Complement.Alter.Med.2011:e238208.(SCI)[IF=2.629,Integrative&complementarymedicine,12/29=41.4%;Q2].(SCI) 126.T.C.Tsai,S.H.Wu,H.L.Chen,Y.T.Tung,W.T.K.Cheng,J.C.HuangandC.M.Chen*2011Identificationofsex-specificpolymorphicsequencesingoatamelogeningeneforembryosexing,J.AnimalSci.89(8):2407-2414.(SCI)[IF=3.159;Agriculture,Dairy&AnimalScience,9/79=Top11.4%;Q1].(SCI) 127.Y.T.Chang?,C.M.Chen?,M.Y.Tu,H.L.Chen,S.Y.Chang,T.C.Tsai,Y.T.Wang,andH.L.Hsiao2011Effectsofosteoporosisandnutritionsupplementsonstructuresandnanomechanicalpropertiesofbonetissue,J.Mechan.Behav.Biomed.Materi.4:1412-1420.(SCI)[IF=3.902;MaterialsScienceBiometerials,17/46=37%;Q2].†Co-firstauthor.(SCI) 128.Y.C.Lin,M.C.Lu,H.L.Tang,H.C.Liu,C.H.Chen,K.S.Liu,C.Lin,C.S.Chiou,M.K.Chiang,C.M.Chen*andY.C.Lai*.2011AssessmentofhypermucoviscosityasavirulencefactorforexperimentalKlebsiellapneumoniaeinfections:comparativevirulenceanalysiswithhypermuco-viscosity-negativestrain,BMCMicrobiology11:50.[IF=3.605;Microbiology,50/142=35.2%;Q2](SCI)(獲選為2011年BMCOpenAssess190種期刊中之HighlyAssessedPaper).(SCI) 129.Y.T.Tung,H.L.Chen,C.W.Lai,C.J.Shen,Y.W.Lai,andC.M.Chen*2011Curcuminreducespulmonarytumorigenesisinvascularendothelialgrowthfactor(VEGF)-overexpressingtransgenicmice,Mol.Nutri.FoodRes.55(7):1036-1043.(SCI)[IF=5.914;FoodScience&Technology,9/160=Top5.6%;Q1].pp.1036-1043.(SCI) 130.H.C.Liu,M.S.Jan,Y.C.Lin,T.C.Wu,C.N.Huang,C.M.Chen*,andM.C.Lu*2011Ararepulmonaryzygomycosismanifestedaschronicmediastinitisandbronchialperforation,Eur.Respir.J.38:734-735.(SCI)[IF=16.671;RespiratorySystem,3/96=3.1%;Q1].(SCI) 131.H.J.Lin,J.Y.Chen,C.F.Lin,S.T.Kao,J.C.Cheng,H.L.Chen,andC.M.Chen*2011HepatoprotectiveeffectsofYiGuanJian,anherbalmedicine,inratswithdimethylnitrosamine-inducedliverfibrosis,J.Ethnopharmacol.134:953-960.(SCI)[IF=4.360,Integrative&ComplementaryMedicine,5/29=17.2%;Q1].(SCI) 132.C.C.Yen,C.J.Shen,W.H.Hsu,Y.H.Chang,H.T.Lin,H.L.ChenandC.M.Chen*.2011Lactoferrin:aniron-bindingantimicrobialproteinagainstEscherichiacoliinfection,BioMetals24:585-594.(SCI)[IF=2.949;Biochemistry&MolecularBiology201/298=67.5%;Q3].(SCI) 133.C.C.Yen,Y.W.Lai,H.L.Chen,C.W.Lai,C.Y.Lin,W.Chen,Y.P.Kuan,W.H.Hsu,andC.M.Chen*.2011Aerosolizedhumanextracellularsuperoxidedismutasepreventshyperoxia-inducedlunginjury,PLoSONE6(10):e26870.(SCI)[IF=3.240;MultidisciplinarySciences,29/126=Top23%;Q1].(SCI) 134.H.J.Lin,C.P.Tseng,C.F.Lin,M.H.Liao,C.M.Chen,S.T.KaoandJ.C.Cheng*2011AChineseherbaldecoction,modifiedYiGuanJian,inducesapoptosisinhepaticstellatecellsthroughaROS-mediatedmitochondrial/caspasepathway,Alter.Med.2011:e459531.(SCI)[IF=2.629,Integrative&complementarymedicine,12/29=41.4%;Q2].(SCI) 135.C.M.Hung,C.C.Yeh,H.L.Chen,C.W.Lai,M.F.Kuo,M.H.Yeh,W.Lin,M.Y.Tu,H.C.Cheng,andC.M.Chen*2010Porcinelactoferrinadministrationenhancesperipherallymphocyteproliferationandassistsinfectiousbursaldiseasevaccinationinnativechickens,Vaccine.28:2895-2902.(SCI)[IF=3.641;Medicine,Research&Experimental,72/186=38.7%;Q2].(SCI) 136.C.H.Lin,C.J.Chen,C.M.Chen,S.L.Liao,S.L.Raung,andS.W.Tsai2010Treatmentofatlantoaxialrotatoryfixationwithbotulinumtoxinmuscleblockandmanipulation,J.Chin.Med.Assoc.73:222-224.(SCI)[IF=2.743;Medicine,General&Internal,76/313=24.3%;Q1].pp.222-224.(SCI) 137.C.M.Hung,S.C.Wu,C.C.Yen,M.F.Lin,Y.W.Lai,Y.T.Tung,H.L.Chen,andC.M.Chen*.2010Porcinelactoferrinasfeedstuffadditiveelevatesavianimmunityandpotentiatesvaccination,BioMetals.23:579-587.(SCI)[IF=2.949;Biochemistry&MolecularBiology201/298=67.4%;Q3].(SCI) 138.M.S.Lee,C.H.Lin,T.H.Lee,H.M.Wu,C.C.Huang,L.S.Huang,C.M.ChenandE.H.Cheng*2010AssociationofcreatinkinaseBandperoxiredoxin2expressionwithageandembryoqualityincumuluscells,J.Assist.Reprod.Genet.27:629-639.(SCI)[IF=3.412;Obstetrics&Gynecology,25/83=30.1%;Q2].pp.629-639.(SCI) 139.K.T.Ho§,M.Y.Shiau,Y.H.Chang,C.M.Chen§,S.C.Yang,andC.N.Huang*2010Associationofinterleukin-4promoterpolymorphismsinTaiwanesepatientswithtype2diabetesmellitus,Metabol.Clin.Exp.59:1717-1722.(SCI)[IF=8.694,Endocrinology&Metabolism,11/177=6.2%;Q1](§Equalcontribution)..(SCI) 140.T.C.Tsai,W.Lin,S.H.Yang,W.T.K.Cheng,E.H.Cheng,M.S.Lee,K.Y.Chang,andC.M.Chen*2010GranzymeGisexpressedinthetwo-cellstagemouseembryoandisrequiredforthematernal-zygotictransition,BMCDev.Biol.10:88.[IF=1.978,DevelopmentalBiology,19/40=47.5%;Q2](獲選為2010年BMCOpenAssess190種期刊中之HighlyAssessedPaper).(SCI) 141.F.C.Liu,H.L.Chen,W.Lin,Y.T.Tang,C.W.Lai,A.L.Hsu,andC.M.Chen*2010ApplicationofporcinelipasesecretedbyPichiapastoristoimprovefatdigestionandgrowthperformanceofpostweaningpiglets,J.Agri.FoodChem.58:3322-3329.(SCI).[IF=5.279;Agriculture,Multidisciplinary6/83=Top7.2%;Q1].(SCI) 142.H.L.Chen,Y.W.Lai,C.S.Chen,T.W.Chu,W.Lin,C.C.Yen,M.F.Lin,M.Y.Tu,andC.M.Chen*.2010ProbioticLactobacilluscaseiexpressinghumanlactoferrinelevatesantibacterialactivityinthegastrointestinaltract,BioMetals.23:543-554.(SCI)[IF=2.949;Biochemistry&MolecularBiology201/298=67.5%;Q3].(SCI) 143.Y.J.Chen,J.L.Shen,C.Y.Wu,S.Y.Chu,Y.T.Chang,C.M.ChenandF.Y.Lee2009Elevatedplasmaosteopontinlevelis1associatedwithoccurrenceofpsoriasisandisanunfavorablecardiovascularriskfactorinpatientswithpsoriasis,J.Am.Acad.Dermatol.60(2):225-230.(SCI)[IF=11.527,Dermatology1/89=Top1.1%;Q1].(SCI) 144.C.C.Yen,C.Y.Lin,K.Y.Chong,T.C.Tsai,C.J.Shen,M.F.Lin,C.Y.Su,H.L.ChenandC.M.Chen*2009Lactoferrinasanaturalregimenofselectivedecontaminationofthedigestivetract,J.Infect.Dis.199(4):590-598.(SCI)[IF=5.226,Infectiousdiseases,18/92=Top19.6%;Q1][NaturalNews.com特別報導].(SCI) 145.Y.J.Chen,C.Y.Wu,C.C.Chang,C.J.Ma,M.C.Li,andC.M.Chen*2008NuclearKruppel-likefactor4expressionisassociatedwithhumanskinsquamouscellcarcinomaprogressionandmetastasis,CancerBiol.Ther.7(5):777-782.(SCI)[IF=4.742,Oncology102/308=33.1%;Q2].no.5,pp.777-782.(SCI) 146.H.L.Chen,L.C.Wang,C.H.Chang,C.C.Yen,W.T.K.Cheng,S.C.Wu,C.M.Hung,M.F.Kuo,andC.M.Chen*2008RecombinantPorcineLactoferrinExpressedintheMilkofTransgenicMiceProtectsNeonatalMicefromaLethalChallengewithEnterovirusType71,Vaccine.26:891-898(SCI)[IF=3.641;Medicine,Research&Experimental,72/186=38.7%;Q2].(SCI) 147.H.L.Chen,J.Y.Huang,T.W.Chu,T.C.Tsai,C.M.Hung,C.C.Lin,L.C.Wang,Y.J.Chen,M.F.Lin,andC.M.Chen*2008ExpressionofVP1proteininthemilkoftransgenicmice:Asapotentialoralvaccineagainstforenterovirus71straininfection,Vaccine.26:2882-2889.(SCI)[IF=3.641;Medicine,Research&Experimental,72/186=38.7%;Q2].(SCI) 148.F.C.Liu,H.L.Chen,K.Y.Chong,A.L.Hsu,andC.M.Chen*2008ProductionofrecombinantporcinecolipasesecretedbyPichiapastorisanditsapplicationtoimprovedietaryfatdigestionandgrowthofpostweaningpiglets,Biotech.Prog.24:1333-1341.(SCI)[IF=2.681,FoodScience&Technology,71/160=44.4%;Q2]..pp.1333-1341.(SCI) 149.Y.J.Chen,C.Y.Wu,J.L.Shen,S.Y.Chu,C.K.Chen,Y.T.Chang.andC.M.Chen*2008Psoriasisindependentlyassociatedwithhyperleptinemiacontributingtometabolicsyndrome,ArchDermatol.144(12):1571-1575.(SCI)[IF=4.789,Dermatology;2/63=Top3.2%;Q1].[LeadingNews特別報導].(SCI) 150.C.F.Tu,H.C.Tsai,C.M.Chen,J.M.Lee,T.S.Yang,Y.L.Tseng,N.K.Chou,andP.H.Lee2008Humanleukocyteantigen-DRmatchingimprovedskingraftsurvivalfromtransgenicpigstoaccommodateSCIDmicereconstitutedwithhumanperipheralbloodmononuclearcells,Transplant.Proc.40(2):578-580.(SCI)[IF=1.066,Transplantation24/25=96%;Q4].(SCI) 151.C.M.Chen*,W.E.Chen,C.Y.Chen,J.C.Wu,andH.L.Chen2007DissectingepigeneticalterationsbetweenhepatitisBvirusandhepatitisCvirus-infectedhepatocellularcarcinomausingCpGislandmicroarray,J.Hepatol.46:127.(SCI).[IF=25.083;Gastroenterology&Hepatology2/92=Top2.2%;Q1].(SCI) 152.F.C.Liu,andC.M.Chen*2007CloningmyostatinpropeptidecDNAandconstructionofitsexpressionvector,TaiwanLivestockRes.40:159-168.. 153.F.C.Liu,andC.M.Chen*2007CloningofmyostatincDNAandanalysisoftherelationbetweenbirthweightandmyostatinmRNAexpressionlevelsofneonatalTLRINo.1blackpigs,TaiwanLivestockRes.40:119-128.. 154.K.M.Lin,T.H.Chao,C.M.Chen,L.P.Chen,H.M.Wang,andF.F.Chiang2007MethylationofthePCDH21(Protocadherin-21)geneincolorectalcancer,J.Soc.ColonRectalSurg.18:93-98.(SCI)..pp.93-98.(SCI) 155.S.C.Wu,H.L.Chen,C.C.Yen,M.F.Kuo,T.S.Yang,S.R.Wang,C.N.Weng,C.M.Chen*,andW.T.K.Cheng2007Recombinantporcinelactoferrinexpressedinthemilkoftransgenicmiceenhancesoffspringgrowthperformance,J.Agri.FoodChem.55:4670-4677.(SCI).[IF=5.279;Agriculture,Multidisciplinary5/58=Top8.6%;Q1](榮獲ACS美國化學學會News特別報導；並被撰文收錄於J.Chem.Edu.期刊作為美國高中及大學生物與化學之參考教材).(SCI) 156.F.C.Liu,andC.M.Chen*2007TheeffectofdietaryadditionoftherecombinantcolipaseongrowthperformanceandfatutilizationofTLRIblackpiglets2wkspostweaning,TaiwanLivestockRes.40:169-175..pp.169-175. 157.H.L.Chen,C.C.Yen,C.Y.Lu,C.H.Yu,andC.M.Chen*2006SyntheticPorcineLactoferricinwitha20-ResiduePeptideExhibitsAntimicrobialActivityagainstEscherichiacoli,Staphylococcusaureus,andCandidaalbicans,J.Agri.FoodChem.54:3277-3282.(SCI).[IF=5.279;Agriculture,Multidisciplinary5/58=Top8.6%;Q1].(SCI) 158.H.L.Chen,C.C.Yen,T.C.Tsai,C.H.Yu,Y.J.Liou,Y.W.Lai,M.L.Wang,andC.M.Chen*2006Productionandcharacterizationofhumanextracellularsuperoxidedismutaseinthemethylotrophicyeast,Pichiapastoris,J.Agri.FoodChem.54:8041-8047.(SCI).[IF=5.279;Agriculture,Multidisciplinary5/58=Top8.6%;Q1][ACSNews].(SCI) 159.C.J.Hu,S.D.Chen,D.I.Yang,T.N.Lin,C.M.Chen,T.H.M.HuangandC.Y.Hsu2006Promoterregionmethylationandreducedexpressionofthrombospondin-1afteroxygen-glucosedeprivationinmurinecerebralendothelialcells,J.Cereb.BloodFlowMetabol.26:1519-1526.(SCI)[IF=6.200;Hematology10/93=Top10.8%;Q1].(SCI) 160.C.C.Yen,S.H.Yang,C.Y.Lin,andC.M.Chen*2006Stemcellsinthelungparenchymaandprospectsforlunginjurytherapy,Eur.J.Clin.Invest.36:310-319.(SCI).[IF=4.686;Medicine,General&Internal,48/313=15.3%;Q1].pp.310-319.(SCI) 161.H.L.Chen,Y.W.Lai,C.C.Yen,Y.Y.Lin,C.Y.Lu,S.H.Yang,T.C.Tsai,C.W.LinandC.M.Chen*2005Productionofrecombinantporcinelactoferrinexhibitingantibacterialactivityinmethylotrophicyeast,Pichiapastoris,J.Mol.Microbiol.Biotechnol.8:141-149.(SCI)[IF=0.803;Biotechnology&AppliedMicrobiology152/156=97.4%;Q4].pp.141-149.(SCI) 162.S.H.Wei,T.C.Yip,andC.M.Chen*.2005IdentifyingclinicopathologicalassociationofDNAhypermethylationincancersusingCpGislandmicroarrays.In:DNAMethylationandCancerTherapy,KluwerAcademic.NY,USA.p.107-116.pp.107-116. 163.S.Y.Pai,S.H.Yang,W.T.K.Cheng,C.H.HsuandC.M.Chen*.2004Desensitivitytherapyofallergicairwayinflammationandhyper-reactivitybymammaryspecificexpre. 164.S.H.Tsai,C.M.Chen,C.S.Chang,andG.H.Chen2004EffectofHelicobacterpyloriinfectiononintragastricacidityinpatientswithrefluxesophagitis,J.Gastroenterol.39:821-826.(SCI)[IF=7.527;Gastroenterology&Hepatology,17/92=Top18.5%;Q1].pp.821-826.(SCI) 165.C.M.Chen,H.L.Chen,T.H.C.Hsiau,A.H.A.Hsiau,H.Shi,G.J.R.Brock,S.H.Wei,C.W.Caldwell,P.S.Yan,andT.H.M.Huang2003MethylationtargetarrayforrapidanalysisofCpGislandhypermethylationinmultipletissuegenomes,Am.J.Pathol.163:37-45.(SCI)[IF=4.307;Pathology,12/89=Top13.5%;Q1].(SCI) 166.H.Yang,C.M.Chen,P.S.Yan,T.H.M.Huang,H.Shi,M.Burger,I.Nimmrich,S.Maier,K.Berlin,andC.W.Caldwell2003Theandrogenreceptorgeneispreferentiallyhypermethylatedinfollicularnon-Hodgkin’slymphomas,Clin.CancerRes.9:4034-4042.(SCI)[IF=12.531;oncology,12/308=Top3.4%;Q1].(SCI) 167.S.H.Wei,C.M.Chen,G.Strathdee,J.Harnsomburana,C.R.Shyu,F.Rahmatpanah,H.Shi,S.W.Ng,P.S.Yan,K.P.Nephew,R.Brown,andT.H.M.Huang2002Methylationmicroarrayanalysisoflate-stageovariancarcinomasdistinguishesprogression-freesurvivalinpatientsandidentifiescandidateepigeneticmarkers,Clin.CancerRes.8:2246-2252.(SCI)[IF=12.531;oncology,12/308=Top3.4%;Q1].(SCI) 168.C.M.Chen*,C.H.Wang,S.C.Wu,C.C.Lin,S.H.Lin,andW.T.K.Cheng2002TemporalandspatialexpressionofbiologicallyactivehumanfactorVIIIinthemilkoftransgenicmicedrivenbymammary-specificbovine-lactalbuminregulationsequences,TransgenicRes.11:257-268.(SCI)[IF=2.788;BiochemicalResearchMethods,46/77=59.7%;Q3].(SCI) 169.J.C.Wu,C.M.Chen,T.Y.Chiang,W.H.Tsai,W.J.Jeng,I.J.Sheen,C.C.Lin,andX.J.Meng2002SpreadofhepatitisEvirusamongdifferent-agedpigs:Two-yearsurveyinTaiwan,J.Med.Virol.66:488-492.(SCI)[IF=2.327;Virology,28/36=77.8%,Q3].(SCI) 170.H.Shi,P.S.Yan,C.M.Chen,F.Rahmatpanah,C.Lofton-Day,C.W.Caldwell,andT.H.M.Huang2002ExpressedCpGislandsequencetagmicroarrayfordualscreeningofDNAhypermethylationandgenesilencingincancercells,CancerRes.62:3214-3220.(SCI)[IF=12.701;oncology,20/308=Top6.5%;Q1].(SCI) 171.C.M.Chen,H.L.Chen,H.Shi,C.W.Caldwell,G.J.R.Brock,P.S.Yan,andT.H.M.Huang2002ComplexpatternsofDNAmethylationincancer,In:CancerEpigenetics:DNAmethylationandchromatin.Madrid,Spanish..pp.43-44. 172.P.S.Yan,C.M.Chen,H.Shi,F.Rahmatpanah,S.H.Wei,andT.H.M.Huang2002ApplicationsofCpGislandmicroarraysforhigh-throughputanalysisofDNAmethylation,J.Nutri.132:2430-2434.(SCI)[IF=4.798;Nutrition&Dietetics,17/103=Top16.5%;Q1].(SCI) 173.S.C.Liu,C.M.Chen,andY.H.Yu2002Sexidentificationofduckembryosbypolymerasechainreaction,TaiwanLivestockRes.35:169-173.pp.169-173. 174.R.S.Gitan,H.Shi,C.M.Chen,P.SYan,andT.H.M.Huang2002Methylation-specificoligonucleotidemicroarray:Anewpotentialforhigh-throughputmethylationanalysis,GenomeRes.12:158-164.(SCI)[IF=9.043;Genetics&Heredity,7/183=Top3.8%;Q1].pp.158-164.(SCI) 175.G.J.R.Brock,T.H.M.Huang,C.M.Chen,andK.J.Johnson2001AnoveltechniquefortheidentificationofCpGislandsexhibitingalteredmethylationpatterns(ICEAMP),Nucl.AcidsRes.29(24):e123.(SCI)[IF=16.971;Biochemistry&MolecularBiology,4/300=Top1.3%;Q1].(SCI) 176.P.S.Yan,C.M.Chen,H.Shi,F.Rahmatpanah,S.H.Wei,C.W.Caldwell,andT.H.M.Huang2001DisectingcomplexepigeneticalterationsinbreastcancerusingCpGislandmicroarrays,CancerRes.61:8375-8380.(SCI)[IF=12.701;oncology,20/308=Top6.5%;Q1].(SCI) 177.C.M.Chen*,Y.C.Chang,H.L.Chen,andW.T.K.Cheng2000/08High-levelexpressionofgrowthhormoneinthemethylotropicyeastanditsapplicationongrowthimprovementoffowls,Asian-Aus.J.Anim.Sci.13:158-161.(SCI)[IF=2.509;Biochemistry&MolecularBiology,17/79=21.5%;Q1].(SCI) 178.W.T.K.Cheng,C.H.Lee,C.M.Hung,T.J.ChangandC.M.Chen*2000/05GrowthhormonegenepolymorphismsandgrowthperformancetraitsinDuroc,LandraceandTao-Yuanpigs,Theriogenology54:1225-1237.(SCI)[IF=2.740;ReproductiveBiology,5/33=Top15.1%;Q1].pp.1225-1237.(SCI) 179.C.M.Hung,T.H.Hong,C.H.Hsu,andC.M.Chen*2000Productionofanti-insulinmonoclonalantibodybyanovelimmunizationprotocolanditsclinicalapplicationtoELISAofinsulin,J.Agri.Soci.China1:343-352.pp.343-352. 180.C.M.Chen,WinstonT.K.Cheng,Y.C.Chang,T.J.Chang,andC.L.Chen2000Growthenhancementoffowlsbydietaryadministrationofrecombinantyeastculturescontainingenrichedgrowthhormone,LifeSci.67:2103-2115.(SCI)[IF=5.037;Medicine,Research&Experimental,35/186=18.8%;Q1].pp.2103-2115.(SCI) 181.J.C.Wu,C.M.Chen,W.H.Tsai,T.Z.Chen,andS.D.Lee2000ClinicalandepidemiologicalimplicationsofswinehepatitisEvirusinfection,J.Med.Virol.60:166-171.(SCI)[IF=2.327;Virology,24/36=66.7%;Q3].pp.166-171.(SCI) 182.C.M.Chen,C.L.Hu,andW.T.K.Cheng1999Thetechniquesofbovineembryosexing,Natl.Sci.Coun.Monthly(ROC).vol.27,pp.381-392. 183.M.F.Kuo,C.M.Chen,H.K.Hu,andW.T.K.Cheng.1999Thefeasiblenessofusingmouseembryonicstemcellsafterretrovirusvector-PSNtransfectiontoaggregatewithmousediploidandtetraploidembryosforproductionoftransgenicmice,.Chin.Soc.Anim.Sci.28:471-490..pp.471-490. 184.C.M.Chen,C.L.Hu,C.H.Wang,C.M.Hung,H.K.Wu,K.B.Choo,andW.T.K.Cheng1999Genderdeterminationinsinglebovineblastomeresbypolymerasechainreactionamplificationofsex-specificpolymorphicfragmentsintheamelogeningene,Mol.Reprod.Dev.54:209-214.(SCI)[IF=2.609;ReproductiveBiology,21/30=70%;Q3].pp.209-214.(SCI) 185.M.F.Kuo,C.M.Chen,H.K.Hu,andW.T.K.Cheng1998Integrationandexpressionofporcinegrowthhormonegeneaftertransfectedintothemouseembryonicstemcellsbyretroviralvector,J.Chin.Soc.Anim.Sci.27(1):59-73..pp.59-73.(SCI) 186.M.F.Kuo,C.M.Chen,H.K.Hu,andW.T.K.Cheng.1998Useofnonautologousmicroencapulatedfibroblastsingrowthhormonegenetherapytoimprovegrowthofmidgetswine,Hum.GeneTher.9:1995-2003.(SCI)[IF=5.695;Biotechnology&AppliedMicrobiology,19/161=Top11%;Q1].pp.59-73.(SCI) 187.K.B.Choo,C.M.Chen,andW.T.K.Cheng.19961996Molecularanalysisofcellularlocidisruptedbypapillomavirus16integrationincervicalcancer:frequentviralintegrationintopologicallydestabilizedandtranscriptionallyactivechromosomalregions,J.Med.Virol.49:15-22.(SCI)[IF=2.327;Virology,28/36=77.8%;Q4].pp.15-22.(SCI) 188.J.C.Wu,C.M.Chen,T.Z.Chen,S.D.Lee,F.S.Yen,andK.B.Choo,1996PrevalenceandtypeofprecorehepatitisBvirusmutantsinhepatitisDvirussuperinfectionanditsclinicalimplications,J.Infect.Dis.173:457-459.(SCI)[IF=5.226,Infectiousdiseases,18/92=Top19.6%;Q1].(SCI) 189.J.C.Wu,C.M.Chen,I.J.Sheen,S.D.Lee,H.M.Tzeng,andK.B.Choo1996EvidenceoftransmissionofhepatitisDvirustospousesfromsequenceanalysisoftheviralgenome,Hepatology22:1656-1660.(SCI)[IF=17.425;Gastroenterology&Hepatology,6/131=Top4.6%;Q1].(SCI) 190.K.B.Choo,C.J.Huang,C.M.Chen,C.P.Han,andL.C.Au1995Jun-Boncogeneaberrationsincervicalcancercelllines,CancerLetters93:249-253.(SCI)[IF=8.679;Oncology,27/308=Top8.8%;Q1].pp.249-253.(SCI) 191.C.M.Chen,W.T.K.Cheng,andK.B.Choo,1995FrequentdeletionsandsequenceaberrationsatthetransgenejunctionsoftransgenicmicecarryingthepapillomavirusregulatoryandtheSV40TAggenesequences,TransgenicRes.4:52-59.(SCI)[IF=2.788;Biochemistry&MolecularBiology,211/298=70.8%;Q3].pp.52-59.(SCI) 192.J.C.Wu,K.B.Choo,C.M.Chen,T.Z.Chen,andS.D.Lee1995GenotypingofhepatitisDvirusbyrestriction-fragmentlengthpolymorphismandrelationtooutcomeofhepatitisD,Lancet346:939-941.(SCI)[IF=79.321;Medicine,General&Internal,2/169=1.2%;Q1].(SCI) 193.K.B.Choo,C.M.Chen,C.N.Shen,andL.C.Au,1995Resolutionofuncertaintiesinrestrictionmapsofcosmidclonesby,Anal.Biochem.288:355-357.(SCI)[IF=3.365;Biochemistry&MolecularBiology,135/300=45.0%;Q2].pp.355-357.(SCI) 194.C.M.Chen*,W.T.K.Cheng,andK.B.Choo1994/06Structureanalysisoftransgenesintransgenicmice:evidenceforfrequentdeletions,insertionsandsequenceaberrations.,Asian-Aus.J.Anim.Sci.7:15-18.(SCI)[IF=2.509;Agriculture,Dairy&AnimalScience,14/63=22.2%;Q1].pp.15-18.(SCI) 195.K.B.Choo,andC.M.Chen,1994Cellulargenesandsequencesdisruptedbyhumanpapillomavirusintegrationincervicalcancer,J.Cell.Biochem.18A:224-225.(SCI)[IF=4.429;Biochemistry&MolecularBiology,112/298=37.9%;Q2].pp.224-225.(SCI) 196.C.M.Chen,M.P.Shyu,L.C.Au,H.W.Chu,W.T.K.Cheng,andK.B.Choo1994AnalysisofdeletionoftheintegratedHPV16sequencesincervicalcancer:arapidmultiplexPCRapproach,J.Med.Virol.44:206-211.(SCI)[IF=2.327;Virology,28/36=77.8%;Q4].pp.206-211.(SCI) 197.K.Y.Chong,C.M.Chen,andK.B.Choo1993Post-hybridizationrecoveryofDNAfrommembranefilterforpolymerasechainreaction(PCR)amplification.,BioTechniques14:575-578.(SCI)[IF=1.993;Biochemistry&MolecularBiology,253/298=84.9%;Q4].pp.575-578.(SCI) B.研討會論文  1.Y.H.Chen(陳昱璇),H.L.Chen,J.K.Chen,andC.M.Chen*.2020Kefirpeptidesimprovegutandbloodvesselsfunctionbyamelioratingintestinalmorphologyandenrichingintestinalmicrobiotainsalt-inducedspontaneoushypertensionratstroke-prone(SHRSP)animalmodel,InThe2020ExperimentalBiologyInternationalConference.Apr.4-7,2020.SanDiego,California,USA.FASEBJ.34(Suppl1):1-1.doi.org/10.1096/fasebj.2020.34.s1.09618. 2.C.M.Chen*,J.C.Yang,C.C.Yen,andH.L.Chen.2020Amnioticfluidmesenchymalstemcellsamelioratelungalveolarepitheliumregenerationandreverselungfibrosisofchronicobstructivepulmonarydisease,InThe2020ExperimentalBiologyInternationalConference.Apr.4-7,2020.SanDiego,California,USA.L9646.FASEBJ.34(Suppl1):1-2.doi.org/10.1096/fasebj.2020.34.s1.09646. 3.Y.W.Lan,W.R.Chen,andC.M.Chen*.2020Amnioticfluidmesenchymalstemcellsattenuatechronicalcohol-inducedliverinjuryinaldo-ketoreductase1a1(Akr1a1)knockoutmousemodel,IntheInternationalSocietyforStemCellResearch(ISSCR)AnnualMeeting2020Virtual.Jun.23-27,2020.Boston,Massachusetts,USA.CA:121. 4.Y.C.Chen,Y.W.Lan,andC.M.Chen*.2020Effectsofamnioticfluidmesenchymalstemcellsonpancreaticadenocarcinomadevelopment,IntheInternationalSocietyforStemCellResearch(ISSCR)AnnualMeeting2020Virtual.Jun.23-27,2020.Boston,Massachusetts,USA.CA:122. 5.C.C.Yang,Y.W.Lan,andC.M.Chen*.2020Amnioticfluidmesenchymalstemcellspreconditionedbyhyperoxicexposurebodyfluidimprovetherapeuticefficacyinthehyperoxicacutelunginjurymousemodel,IntheInternationalSocietyforStemCellResearch(ISSCR)AnnualMeeting2020Virtual.Jun.23-27,2020.Boston,Massachusetts,USA.TSC:366. 6.Y.W.Lan,W.R.Chen,andC.M.Chen*.2020Amnioticfluidmesenchymalstemcellsattenuatechronicalcohol-inducedliverinjuryinaldo-ketoreductase1a1knockoutmousemodel,Inthe2020InternationalConferenceofTaiwaneseSocietyofDevelopmentalBiology.P-13.Aug.7-8,NCHU,Taichung,Taiwan. 7.G.R.L.Chang(張若麟)#,K.I.Chang(張顧議)#,C.K.Peng,H.L.ChenandC.M.Chen*.2020KFP-1,a17-residuekefirpeptide,enhancesintracellularcalciumuptakeandinhibitsRANKL-inducedosteoclastogenesisbyacceleratingosteoclastapoptosis,Inthe2020InternationalConferenceofTaiwaneseSocietyofDevelopmentalBiology.P-14.Aug.7-8,NCHU,Taichung,Taiwan.(SelectedOralPresentation). 8.Y.W.Lai,C.H.Ko,H.L.Chen,andC.M.Chen*.2020Anti-inflammationandboneprotectioneffectsofkefirpeptidesinaratmodelofadjuvant-inducedrheumatoidarthritis,Inthe2020InternationalConferenceofTaiwaneseSocietyofDevelopmentalBiology.P-18.Aug.7-8,NCHU,Taichung,Taiwan. 9.Y.T.Kao(高永璁),Y.W.Lan,andC.M.Chen*.2020AssessmentofInUteroTherapyofHemophiliaMicebyAmnioticFluidStemCellsEngraftment,Inthe2020InternationalConferenceofTaiwaneseSocietyofDevelopmentalBiology.P-57.Aug.7-8,NCHU,Taichung,Taiwan. 10.C.M.Chen*(SectionChair;Co-Organizer)2020Developmentofclinical-grademediumforstemcellcultureandbiomechanicsandfunctioningmechanismsofanimalsuctiondevices,Inthe2020InternationalConferenceofTaiwaneseSocietyofDevelopmentalBiology.Aug.7-8,NCHU,Taichung,Taiwan. 11.C.L.Tsai(蔡忠良),H.L.Chen,andC.M.Chen*.2020Effectsofkefirexopolysaccharideextractonhigh-fatdietandSTZ-inducedtype2diabeticrat,Inthe2020AnnualConferenceofChinesePhysiologySociety.P.19.Aug.16-17,2020.Hui-SunExperimentalForest,Nantau,Taiwan.(*榮獲2020年生醫年會/生理學會壁報論文獎). 12.C.M.Chen*(PlenarySpeaker)2020Developmentandcommercializationofanti-osteoporoticpeptides:Frombasicstudytoclinicaltrial,InThe2020SmartTechnologyForum.Aug.18,2020.NCHU,Taichung,Taiwan. 13.Y.H.Chen(陳昱璇),H.L.Chen,J.K.Chen,andC.M.Chen*.2020Anti-inflammation,antioxidantandantifibroticeffectsofkefirpeptidesonsalt-inducedrenalvasculardamageinstroke-pronehypertensiverats,InThe2020SymposiumonInternationalSocietyofBiocatalysisandAgriculturalBiotechnology.Oct.23-24,2020.SectionNo.2.InternationalConferenceHallofHuisunForestFarm,Nantou,Taiwan.(*榮獲2020年國際生物催化暨農業生技學會論文競賽金獎). 14.G.R.L.Chang(張若麟),K.I.Chang,Y.T.Tung,H.L.Chen,andC.M.Chen*.2020A17-residuekefirpeptideenhancescalciuminfluxinCaco-2cellsandinhibitsRANKL-inducedosteoclastogenesisinBMMsandRaw264.7cells,InThe2020SymposiumonInternationalSocietyofBiocatalysisandAgriculturalBiotechnology.Oct.23-24,2020.SectionNo.2.InternationalConferenceHallofHuisunForestFarm,Nantou,Taiwan.(*榮獲2020年國際生物催化暨農業生技學會論文競賽銀獎). 15.Y.W.Lan(籃英維),H.H.Li(李信翰),H.L.Chen,andC.M.Chen*.2020Kefirpeptidesalleviatehigh-fatdiet-inducedatherosclerosisinApoEknockoutmice,InThe2020SymposiumonInternationalSocietyofBiocatalysisandAgriculturalBiotechnology.Oct.23-24,2020.SectionNo.2.InternationalConferenceHallofHuisunForestFarm,Nantou,Taiwan.(*榮獲2020年國際生物催化暨農業生技學會論文競賽佳作獎). 16.Y.T.Kao(高永璁),Y.W.Lan,andC.M.Chen*.2020Assessmentofinuterotherapyofhemophiliamicebyamnioticfluidstemcellsengraftment,Inthe2020InternationalConferenceonStemCell&GeneTherapy.PO-38.Oct.30-31,NYMU,Taipei,Taiwan. 17.Y.J.Ho(何有容),Y.T.Kao(高永璁),Y.M.Liou*,andC.M.Chen*.2019EffectofvitaminCdeficiencyonosteoclastdifferentiationandsurvivalinAkr1A1geneknockoutmice,Inthe34thJointAnnualConferenceofBiomedicalScience.Mar.15-16,NDMC,Taipei,Taiwan. 18.Y.W.Lai(賴韻文),C.H.Ko,H.L.Chen,andC.M.Chen*.2019Anti-Inflammatoryeffectandboneprotectionofkefirpeptidesinaratmodelofadjuvant-inducedrheumatoidarthritis,InThe2019ExperimentalBiologyInternationalConference.Apr.1-4,2019.Orlando,Florida,USA.FASEBJ.33(Suppl1):lb133. 19.C.M.Chen*(SectionChair).2019Applicationsofmitochondrialtransplantation,Inthe2019Mini-SymposiumofMitochondrialMedicineandResearch.Apr.23,2019.NationalChungHsingUniversity,Taichung,Taiwan. 20.S.L.Chou,G.D.Lai,K.Y.Chang,K.Y.Han,G.R.L.Chang,H.L.Chen,andC.M.Chen*.(InvitedSpeaker).2019Kefir-fermentedpeptidesenhancebonedensityandbiomechanicsinovariectomizedmice,Inthe2ndAmericasConferenceonMedicalImagingandClinicalResearch(AMICR2019).Aug.8-10,2019,Toronto,Canada. 21.C.M.Chen*(Sectionchair;InvitedSpeaker).2019ExperiencesharingoftheMoSTOutstandingResearchAwardwinner,InThe35thTaiwanBiologistsSummerCamp.Aug.25-27,2019.GreatRootsForestryResort,Taipei,Taiwan. 22.C.M.Chen*(Organizer;SectionChair).2019Applicationsofnewbiotechnologyintheanimalindustry,Inthe2019InternationalSymposiumonAnimalBiotechnology.Sep.17-19,2019.NationalChungHsingUniversity,Taichung,Taiwan. 23.S.Y.T.Kao(高永璁),Y.W.Lan,andC.M.Chen*.2019Assessmentofinuterotherapyofhemophiliamicebyamnioticfluidstemcellsengraftment,Inthe2019InternationalConferenceofStemCellsResearch-FromStemCellBiologytoNewTherapies.Nov.6-8,2019,Toronto,Canada. 24..C.M.Chen*(InvitedPlenarySpeaker).2019Applicationsofanimalbiotechnologyonagricultureandbiomedicalsciences,InThe2019TaiwanAgriculturalBioeconomicConference:TheOpportunitiesofFutureBioindustry.Oct.2,2019.NationalTaiwanUniversity,Taipei,Taiwan. 25.Y.W.Lan(籃英維),J.C.Yang,C.M.Chen*,andK.Y.Chong.2018Pre-differentiatedamnioticfluidmesenchymalstemcellsenhancelungalveolarepitheliumregenerationandreverseelastase-inducedpulmonaryemphysema,Jun.20-23,2018.Melbourne,Australia.(*TravelAward). 26.C.M.Chen*(InvitedSpeaker).2018nti-osteoporoticpeptidesderivedfromkefirfermentationandtheirapplicationonclinicaluses,InThe2018Middle-TaiwanBreastCancerSymposium.Jan.13-14,2018.MillenniumHotelsandResorts.Taichung,Taiwan. 27.Y.T.Kao(高永璁),Y.T.Chen,Y.W.Lan,andC.M.Chen*.2018InuterotherapyforhemophiliaAusingEGFPamnioticfluidstemcells,InThe2018ExperimentalBiologyInternationalConference.Apr.20-24,2018.SanDiego,CA,USA.FASEBJ.32(Suppl1):816.10. 28.W.R.Chen(陳婉如),Y.W.Lan,H.L.Chen,andC.M.Chen*.2018AKR1A1deficiencyisassociatedwithhighriskofalcohol-inducedfattyliversyndrome,InThe2018ExperimentalBiologyInternationalConference.Apr.20-24,2018.SanDiego,CA,USA.FASEBJ.32(Suppl1):546.6. 29.W.Y.Cheng(鄭惟元),Y.W.Lan,H.L.Chen,andC.M.Chen*.2018AtherogenicdietinducedcardiovasculardiseaseandbonelossinApoEknockoutmice,InThe2018ExperimentalBiologyInternationalConference.Apr.20-24,2018.SanDiego,CA,USA.FASEBJ.32(Suppl1):676.8. 30.C.M.Chen*(Sectionchair;Organizer),2018Howtooperatelaboratoryandwritingafundablegrantproporsal?,InThe34thTaiwanBiologistsSummerCamp.Jun.26-28,2018.NationalQuemoyUniversity.Kinman,Taiwan. 31.T.HSun(孫子惠),Y.W.Lan,C.M.Chen*.2018MechanismsofKFPimprovingfattyliverdiseasethroughOB-Rb/JAK2pathwayinob/obknockoutmice,Inthe2018InternationalConferenceonBiomedicalSciences.Jun.29-30,2018.CMU,Taichung,Taiwan.(*榮獲2018年生物醫學國際研討會壁報論文競賽優等獎). 32.Y.T.Kao(高永璁),Y.T.Chen,Y.W.Lan,C.M.Chen*.2018InuterotherapyforhemophiliaAusingEGFPamnioticfluidstemcells,Inthe2018InternationalConferenceonBiomedicalSciences.Jun.29-30,2018.CMU,Taichung,Taiwan.(*榮獲2018年生物醫學國際研討會壁報論文競賽佳作獎). 33.W.Y.Cheng(鄭惟元),Y.W.Lan,H.H.Li,C.M.Chen*.2018Atherogenicdiet-inducedcardiovasculardiseaseandbonelossinApoE-/-knockoutmice,Inthe2018InternationalConferenceonBiomedicalSciences.Jun.29-30,2018.CMU,Taichung,Taiwan.(*榮獲2018年生物醫學國際研討會壁報論文競賽佳作獎). 34.W.R.Chen(陳婉如),C.W.Lai,Y.W.Lan,C.M.Chen*.2018Akr1A1deficiencyisassociatedwithhighriskofalcohol-inducedfattyliversyndrome,Inthe2018InternationalConferenceonBiomedicalSciences.Jun.29-30,2018.CMU,Taichung,Taiwan.(*榮獲2018年生物醫學國際研討會壁報論文競賽佳作獎). 35.C.M.Chen*(SectionChair;Co-Organizer).2018Advancebiomedicalconceptsandtools,IntheAsia-PacificSocietyforBiologyandMedicalSciences(APSBMS)2018AnnualMeeting.Jul.20-23,2018.Hokkaido,Japan. 36..K.S.Hsiao,C.M.Chen,C.K.Chuang,S.H.Peng,M.T.Chiou,S.W.Hung,C.M.Chen,andC.F.Tu*(Oral).2018GeneeditedpigletsnullporcineCMAHexpressiondon’tresistanttoporcineepidemicdiarrheavirusinfection,Inthe18thAsian-AustralasianAnimalProduction(AAAP)Congress2018.Aug.1-5,2018.Kuching,Sarawak,Malaysia. 37.C.M.Chen*(PlenarySpeaker;SectionChair;Co-Organizer).2018ExpressionofVP1proteininthemilksoftransgenicmice:Asapotentialoralvaccineagainstforanew-identifiedEnterovirus71straininTaiwan,InThe3rdChina-TaiwanBilateralForumonAnimalBiotechnology.Sep.18-21,2018.ShandongAgriculturalUniversity,Shandong,China. 38.C.M.Chen*(PlenarySpeaker;SectionChair;Organizer).2018Thedevelopmentofanti-osteoporoticpeptides:Frombasicresearchtoclinicaltrial,InThe2018BioGroupSymposium_MeetupwithBiotechTalents.Dec.21,2018.P.18.NationalChungHsingUniversity,Taichung,Taiwan. 39.C.M.Chen*(InvitedPlenarySpeaker).2017Thefunctionalstudyofanti-osteoporoticpeptides:Frombasictoclinical,InThe2017TaiwanAcademyofPhysicalMedicineandRehabiliation.LuncheonSymposium.Mar.11-12,2017.Taipei,Taiwan. 40.C.M.Chen*(InvitedParallelSectionChair).2017CancerEpigenomicsFirstSection,InThe3rdTaiwanEpigenomicsSymposiumandInternationalConferenceonSystemsBiology.Mar.17-18,2017.NCCU,Chia-Yi,Taiwan. 41.C.M.Chen*,Y.A.Tsou,andH.L.Chen.2017LactoferrininteractswithSPLUNC1toamelioatelipopolysaccharideinducedinflammationofhumannasalepithelialcells,InThe2017ExperimentalBiologyInternationalConference.ASIP-3547.Apr.22-26,2017.Chicago,IL,USA.FASEBJ.31(Suppl1):760.7. 42.Y.H.Chen(陳昱璇),H.L.Chen,andC.M.Chen*.2017Establishmentofsalt-inducedchronickidneydiseaseinstroke-pronespontaneouslyhypertensiverats(SHRSP)anditstherapeuticeffectofkefir-derivedpeptidesoraladministration,InThe2017ExperimentalBiologyInternationalConference.Apr.22-26,2017.Chicago,IL,USA.FASEBJ.31(Suppl1):855.12. 43.Y.T.Chen(陳彥廷),H.L.Chen,andC.M.Chen*.2017AnovelgenetherapyinhemophiliaAmousemodelbyusinglipid-coatedFe3O4nanoparticles,InThe2017ExperimentalBiologyInternationalConference.ASIP-3349.Apr.22-26,2017.Chicago,IL,USA.FASEBJ.31(Suppl1):984.2. 44.W.Y.Lin(林煒峪),R.L.Chang,Y.W.Liu,andC.M.Chen*.2017Histopathologicaldissectionofthreedifferentosteoporosisanimalmodelsincludingovariectomyfemale,FⅧknockoutandAkr1A1knockoutmice,InThe2017ExperimentalBiologyInternationalConference.Apr.22-26,2017.Chicago,IL,USA.FASEBJ.31(Suppl1):976.4. 45.H.Ou-Yang(歐陽桓),S.C.Wu,L.Y.Sung,andC.M.Chen*.2017Stat3isaupstreamregulatorofGranzymegthattriggertheminorzygoticgeneacitvationinmousepreimplantationembryo,InThe2017ExperimentalBiologyInternationalConference.ASBMB-3363.Apr.22-26,2017.Chicago,IL,USA.FASEBJ.31(Suppl1):765.8. 46.Y.W.Lan,J.C.Yang,K.Y.Chong,andC.M.Chen*.2017Transplantationoflungepithelialprogenitorspre-differentiatedamnioticfluidmesenchymalstemcellsattenuatedelastase-inducedpulmonaryemphysema,InThe2017DevelopmentalBiologyInternationalConference.Jul.12-15,2017.Amstrdam,Nwrgerlands.Mech.Develop.145:S167. 47.C.M.Chen*(InvitedSpeaker),Y.T.Tung,H.S.Wu,andH.L.Chen.2017Kefirpeptidespreventhyperlipidemiaandobesityinhighfatdiet-inducedobeseratsvialipidmetabolismmodulation,InThe2017InternationalCongressonObesityandMetabolicSyndrome(ICOMS).Aug.31-Sep.3,2017.Seoul,Korea. 48.H.L.Chen,T.C.Tsai,Y.C.Tsai,andC.M.Chen*.2017Kefirpeptidespreventhigh-fructosecornsyrup-inducednon-alcoholicfattyliverdiseaseinamurinemodelbymodulationofinflammationandtheJAK2signalingpathway,InThe2017InternationalCongressonObesityandMetabolicSyndrome(ICOMS).Aug.31-Sep.3,2017.Seoul,Korea. 49.C.M.Chen*(PlenarySpeaker;Organizer)2017High-performanceproductionsofporcinelactoferrinanditsantimicrobialmechanismstudyforanimalindustrialapplications,InThe2ndChina-TaiwanBilateralForumonAnimalBiotechnology.Oct.23-26,2017.NationalChungHsingUniversity,Taichung,Taiwan. 50.C.M.Chen*(InvitedSpeaker),P.Y.Wu,C.H.Liao,andH.L.Chen.2017ExpressionoflactoferrininPichiapastorisinductionbyglucoseinamodifiedG1promotersystemanditsantimicrobialandantitumoractivities,InThe13thInternationalConferenceonLactoferrin,Structure,FunctionandApplications.Nov.5-10,2017.Rome,Italy. 51.H.L.Chen,W.H.Chang,C.C.Yen,andC.M.Chen*.2017Lactoferrinactsasanaturalantioxidantprotectinglungsandkidneyssystemicinflammationfromhyperoxicinjury,InThe13thInternationalConferenceonLactoferrin,Structure,FunctionandApplications.Nov.5-10,2017.Rome,Italy. 52.Y.W.Liu(劉耀文)andC.M.Chen.2016Thefunctionalassessmentsofkefir-fermentedpeptidestopreventbonelossandmicroarchitectureinagenetic-deficientosteoporosismodelofclottingfactorVIIIknockoutmice,Inthe31thJointAnnualConferenceofBiomedicalScience.P256.Mar.26-27,NDMC,Taipei,Taiwan. 53.C.M.Chen*(InvitedSpeaker),C.C.Yen,H.L.Chen,andS.M.Wang.2016Aerosolizedprebioticlactoferrinreduceslunginjuryandfibrosisaftermoderatehyperoxicexposureviatheanti-oxidationpathway,InThe2ndProbioticsInternationalCongress:Asia.P6.Feb.28-Mar.2,2016.KualaLumpur,Malaysia. 54.H.L.Chen,Y.T.Tung,C.L.Tsai,andC.M.Chen*.2016Kefirimprovesfattyliversyndromebyinhibitingthelipogenesispathwayinleptin-defectiveob/obknockoutmice,InThe2ndProbioticsInternationalCongress:Asia.P4.Feb.28-Mar.2,2016.KualaLumpur,Malaysia. 55.C.M.Chen*(InvitedSpeaker).2016Currentdevelopmentofanimalbiotechnologyanditsapplicationsinbiomedicalsciences,InThe2016SymposiumonMolecularandBiologicalSciences.Mar.30-Apr.1,2016.ShandongAgriculturalUniversity,Shandong,China. 56.C.M.Chen*(InvitedSpeaker).2016Novelbiotechnologyofmilk-derivedpeptidesanditsapplicationsinbiomedicalscienceandclinicaluse,InThe2016SymposiumonBiomedicalandBio-agriculturalTechnologyDevelopmentinTaiwan.Jul.13-14,2016.NationalChengKungUniversity,Tainan,Taiwan. 57.H.C.Tsai,L.C.Huang,T.P.Lee,S.C.Wu,andC.M.Chen*.2016Studyofplateletrichplasmaandplateletpatchfortheacutewoundshealinginmini-piganimalmodel,Inthe5thCongressofWorldUnionofWoundHealingSocieties(WUWHS).Sep.25-29,2016.Florence,Italy. 58.P.Y.WuandC.M.Chen*(InvitedSpeaker).2016ConstitutiveexpressionofporcinelactoferrininPichiapastorisinducedbyglucose,anovelG1promotersystem,InThe12thInternationalSymposiumonBiocatalysisandAgriculturalBiotechnology(ISBAB).Oct.16-20,2016.UniversityofHongKong.HongKong. 59.M.Y.Tu,K.Y.Chang,C.F.Chen,Z.J.Lai,H.L.ChenandC.M.Chen*(InvitedSpeaker).2016ImprovementsofKefir-fermentedpeptidesonbonemineraldensityandbonemetabolisminarandomizedclinicaltrialofosteoporoticpatients,InThe71thJointAnnualConferenceofTaiwanOrthopaedicAssociation.Oct.22-23,2016.Oral:O-055.Taipei,Taiwan. 60.M.Y.Tu,K.Y.Chang,C.F.Chen,Z.J.Lai,H.L.ChenandC.M.Chen*.2016Kefirpeptidesattenuatedbonelossandimprovedfemurmicroarchitectureinanovariectomizedratmodelofpostmenopausalosteoporosi,InThe71thJointAnnualConferenceofTaiwanOrthopaedicAssociation.Oct.22-23,2016.Oral:SY042.Taipei,Taiwan. 61.J.C.Yang(楊景程),Y.W.Lan,K.C.ChongandC.M.Chen*.2016Differentiatedandpre-differentiatedamnioticfluid-derivedmesenchymalstemcellsinmouseemphysemamodelforlungepitheliumrepairing,InThe12thAnnualConferenceoftheSocietyforStemCellResearch.C3.Oct.1-2,2016.CMU,Taichung,Taiwan. 62.C.M.Chen*(InvitedSpeaker),Y.T.Tung,andH.L.Chen.2016ActivecomponentofDanshen(SalviamiltiorrhizaBunge),TanshinoneI,attenuatesVEGF-inducedlungtumorigenesis,InThe12thCross-StraitSymposiumonPlantMolecularandBiotechnology.O12.Nov.2-4,2016.I-ShouUniversity,Kaohsiung,Taiwan. 63.C.M.Chen*(InvitedSpeaker;Organizer).2016SexuallydimorphicexpressionofeGFPtransgeneintheAkr1A1locusofmouseliverregulatedbysexhormone-relatedepigeneticremodeling,InThe2016BilateralSymposiumonAgriculturalBiotechnology.Nov.8-11,2016.Wuhan,China. 64.Y.T.Chen(陳彥廷),T.C.Tsai,P.S.LaiandC.M.Chen*.2016novelgenetherapyinhemophiliaAinheriteddiseasemousemodel:Usingthemagnetic-coatingmaterials(DPPC-Fe3O4)astheDNAcarrier,InThe14thAnnualConferenceoftheChinese-TaipeiSocietyofLaboratoryAnimalSciences.PT-45,Nov.24-25,2016.AcademiaSinica,Taipei,Taiwan.(*榮獲2016年中華實驗動物學會第十四屆學術研討會壁報論文競賽優勝獎). 65.H.H.Li(李信翰),H.L.Chen,andC.M.Chen*.2016InductionofcardiovasculardiseasesinApoE-/-knockoutmiceandthefunctionalassessmentsofkefirpeptidesinimprovingofvascularendotheliumandthepreventionofatherosclerosis,InThe14thAnnualConferenceoftheChinese-TaipeiSocietyofLaboratoryAnimalSciences.PT-49,Nov.24-25,2016.AcademiaSinica,Taipei,Taiwan. 66.W.Y.Lin(林煒峪),C.W.Lai,H.L.Chen,andC.M.Chen*.2016NutritionalimbalancedosteoporosismousemodelofvitaminCdeficiencybyAkr1A1geneknockout,InThe14thAnnualConferenceoftheChinese-TaipeiSocietyofLaboratoryAnimalSciences.PT-46,Nov.24-25,2016.AcademiaSinica,Taipei,Taiwan.(*榮獲2016年中華實驗動物學會第十四屆學術研討會壁報論文競賽優勝獎). 67.Y.H.Chen(陳昱璇),H.L.Chen,andC.M.Chen*.2016Establishmentofsalt-inducedchronickidneydiseaseanimalmodelinstroke-pronespontaneouslyhypertensiverats(SHRSP)andameliorationofkidneydamagebykefir-derivedpeptidesoraladministration,InThe14thAnnualConferenceoftheChinese-TaipeiSocietyofLaboratoryAnimalSciences.PT-43,Nov.24-25,2016.AcademiaSinica,Taipei,Taiwan.. 68.P.Y.Wu(吳佩穎),G.L.ChangandC.M.Chen*.2016HighlyexpressionofantimicrobiallactoferrininG1promotersystemofPichiapastorisinducedbyglucose,InThe22thFirstGeneralAssemblyandSymposiumonTaiwanSocietyofMicrobiology.AM16,Dec.11,2016.NationalTaiwanUniversity,CollegeofMedicine,Taipei,Taiwan.(*榮獲第二十二屆台灣微生物學研討會應用微生物組論文競賽第一名). 69.C.M.Chen*(PlenarySpeaker;Co-Organizer).2016Currentdevelopmentofanimalbiotechnologyanditsapplicationsintheanimalsciences,InThe1stChina-TaiwanBilateralForumonAnimalBiotechnology.Dec.13-16,2016.ShandongAgriculturalUniversity,Shandong,China. 70.J.C.Yang,H.L.ChenandC.M.Chen*.2015/10Anovelstemcelltherapyapproachameliorateshyperoxia-inducedacutelunginjurybydifferentiatedamnioticfluidstemcellsintolungprogeitorcells.,InThe2015InternationalConferenceonStemCellsandDevelopmentalBiology..Oct.16-17,2015.PosterNo.34.Taipei,Taiwan.. 71.C.M.Chen*(InvitedSpeaker;Organizer)2015/10Lungtumorigenesisinducedbyhumanvascularendothelialgrowthfactor(hVEGF)overexpressionintransgenicmiceandameliorationoftumorformationbymiR-16.,InThe2015SymposiumonAgriculturalandBiologicalSciences..Oct.27-31,2015.Guangxi,China.. 72.Y.S.HuangandC.M.Chen*.(SectionChair)2015/09TheapoptosiseffectoflactoferrinontheHBV-inducedhepatocellularcarcinoma.,InThe2015SymposiumonApplicationofTaiwan'sAgriculturalBiotechnologyandNaturalResources..Sep.3-4,2015.Nantou,Taiwan.. 73.C.M.Chen*(InvitedSpeaker)2015/09LactoferrinpreventsDMN-inducedchemicalinjuryofliverfibrosisbyinhibitingstellatecellactivation.,InThe11thInternationalSymposiumonBiocatalysisandAgriculturalBiotechnology..Sep.13-15,2015.Banff,Alberta,Canada.. 74.C.W.KuoandC.M.Chen*(InvitedSpeaker)2015/09Extracellularsuperoxidedismutasewithheparinbindingdomainretardtheprogressionofstreptozotocin-induceddiabeticnephropathy.,InThe4thInternationalConferenceonNephrologyandTherapeutics..Sep.14-16,2015.Baltimore,USA.. 75.C.M.Chen*,Y.T.Tung,P.W.Huang,Y.C.Chou,D.C.Yeh,andJ.L.Wang.2015/03Dissectionoflungtumorigenesisinducedbyhumanvascularendothelialgrowthfactor(hVEGF)-A165overexpressioninClaracellsoftransgenicmice.,InThe2015ExperimentalBiologyInternationalConference..Mar.28-Apr.1,2015.Boston,MA,USA.. 76.T.C.Tsai,Y.T.Tung,Y.H.Kuo,J.W.Liao,H.C.Tsai,K.Y.Chong,H.L.Chen,andC.M.Chen*.2015/03Anti-inflammatoryeffectsofAntrodiacamphorataanditsactivecompound,ergostatrien-3β-ol,inamouseskinischemiamodel.,InThe2015ExperimentalBiologyInternationalConference..Mar.28-Apr.1,2015.Boston,MA,USA.. 77.C.M.Chen*(InvitedSpeaker),J.Y.Chen,T.Y.Tang,andH.L.Chen.2015Recombinantporcinelactoferrinproductionanditsapplicationonprotectingchemicalinjuryofliverfibrosisinanimalmodel,InThe12thInternationalConferenceonLactoferrin,Structure,FunctionandApplications.Nov.2-6,2015.Nagoya,Japan.. 78.H.C.Liu,H.C.Chen,T.C.Tsai,Y.C.Lee,H.C.Chang,andC.M.Chen*2015Theoralimmunotherapyofhousedustmiteextractsingestioninamurinemodelofallergicasthma,InThe20thCongressoftheAsianPacificSocietyofRespirology.Dec.3-6,2015.KualaLumpur,Malaysia. 79.C.W.Lai(賴政威),H.L.ChenandC.M.Chen*.2014/10Thesystemicpromoterdriving-EGFPtransgenicmicerepresentasexualdimorphicEGFPexpressioninliver:controlledbytestosteroneduringthepubertalperiodofmice.,Inthe15thIUBMBInternationalConferenceon“MolecularMedicineandDrugDiscovery”..PosterNo.G9-6.Oct.21-26,2014.Taipei,Taiwan.. 80.C.M.Chen*,C.J.Shen,W.T.K.Cheng,andH.L.Chen.2014/07Aberrantepigeneticregulationofosteoponingeneinclonedswinegenome.,Inthe2014InternationalConferenceonLifeScienceandBiologicalEngineering..ID:LSBE-1479,Jul.21-24.Sapporo,Japan.. 81.Y.C.Tsai(蔡沂瑾),H.L.Chen,andC.M.Chen*.2014/03KefirpreventsthedevelopmentoffattyliverviaAMPKactivationtoreducelipogenesis,Inthe29thJointAnnualConferenceofBiomedicalScience.P925,Mar.15-16,NDMC,Taipei,Taiwan. 82.H.Ou-Yang(歐陽桓),S.C.Wu,T.C.Tsai,W.T.K.Cheng,andC.M.Chen*.2014/03ThemechanismofgranzymeGspecificexpressedinmouseembryo2-cellstage,Inthe29thJoingAnnualConferenceofBiomedicalScience.P434,Mar.15-16,NDMC,Taipei,Taiwan. 83.H.N.Wu(吳欣珊),H.L.Chen,andC.M.Chen*2014/03Cloningandexpressionofrecombinantwild-typeporcinemyostatinpropeptideanditsmutantforminPichiapastoris.,Inthe29thJointAnnualConferenceofBiomedicalScience..P613,Mar.15-16,NDMC,Taipei,Taiwan.. 84.Y.H.Chen(陳昱璇),H.L.Chen,C.C.Kao,andC.M.Chen*2014/03Kefir-fermentedpeptides(KFP)exhibitinganti-hypertensionandreducingcerebralhemorrhageinstroke-pronespontaneouslyhypertensiverats.,Inthe29thJointAnnualConferenceofBiomedicalScience..P610,Mar.15-16,NDMC,Taipei,Taiwan.(*榮獲2014年第29屆生醫年會_台灣生化與分生學會壁報論文競賽優勝獎). 85.C.W.Lai,S.T.Wen,W.Chen,H.L.Chen,C.C.Yen,K.H.Lee,S.C.WuandC.M.Chen*.2013/11Amnioticfluidstemcellsfromegfptransgenicmiceattenuatehyperoxia-inducedacutelunginjury.,Inthe2013TaiwanSocietyforBiochemistryandMolecularBiology..P01.Nov.22-24.Taichung,Taiwan.. 86.Y.T.Tung,H.L.Chen,C.L.Tsai,andC.M.Chen*.2013/11Kefirimprovesfattyliversyndromebyinhibitingthelipogenesispathwayinleptin-defectiveob/obknockoutmice.,Inthe2013TaiwanSocietyforBiochemistryandMolecularBiology..P21.Nov.22-24.Taichung,Taiwan.. 87.T.C.Tsai,Y.T.Tung,Y.H.Kuo,L.T.Chen,W.H.Chang,andC.M.Chen*.2013/11Anti-inflammatoryeffectsofantrodiacamphorataonhyperoxia-inducedsystemicinflammatoryresponsesinNF-κB/luciferasetransgenicmice.,Inthe2013TaiwanSocietyforBiochemistryandMolecularBiology..P23.Nov.22-24.Taichung,Taiwan.. 88.H.C.Tsai,S.X.Low,andC.M.Chen*.2013/11Dissectingmicrornaprofileinhyperglycemiaandhypoxiawoundhealing.,Inthe2013TaiwanSocietyforBiochemistryandMolecularBiology..P52.Nov.22-24.Taichung,Taiwan.. 89.C.M.Chen*,T.C.Tsai,Y.T.Tung,andH.L.Chen.2013/09Purificationdifferentformsofextracellularsuperoxidedismutaseandtheireffectsonanti-hypertensionthroughnitricoxideinductioninspontaneoushypertensionrats.,InThe13thInternationalConferenceonEndothelin.Sep.8-11,2013.PosterNo:P.71.Tokyo,Japan.. 90.H.L.Chen,T.C.Tsai,Y.T.Tung,andC.M.Chen*.2013/09Identificationandcharacterizationofnovelanti-hypertensivepeptidesobtainedfromfermentedmilk.,InThe13thInternationalConferenceonEndothelin.Sep.8-11,2013.PosterNo:P.72.Tokyo,Japan.. 91.H.L.Chen,T.C.Tsai,J.C.Huang,D.C.Wang,andC.M.Chen*.2013/08Amelogeninallelesonsexchromosomesforgenderdeterminationofpreimplantationgoatembryos.,ICEBB2013,.August24-25,2013.Singapore.. 92.145. Y.T.Tung,H.L.Chen,H.C.Tsai,S.H.Yang,Y.C.Chang,andC.M.Chen*.2013/02Andrographolide,anactivecomponentofAndrographispaniculataNees,fortreatinglungadenocarcinomas.,Inthe5thInternationalConferenceonDrugDiscovery&Therapy(ICDDT)..PosterNo.PO-107.pp.103.Feb.18-21,2013,Dubai,UAE.. 93.M.H.Ho,C.L.Tsai,H.L.Chen,andC.M.Chen*.2013Effectsofkefir-fermentedpeptidesonreductionoflipidaccumulationinhepaticsteatosiscellsinducedbyoleic/palmiticacid,Inthe2013TaiwanSocietyforBiochemistryandMolecularBiology.P66.Nov.22-24.Taichung,Taiwan.. 94.Y.T.Tung,H.L.Chen,H.C.Tsai,S.H.Yang,Y.C.Chang,andC.M.Chen*.2013Therapeuticpotentialofandrographolideisolatedfromtheleavesofandrographispaniculataneesfortreatinglungadenocarcinomas,Inthe2013TaiwanSocietyforBiochemistryandMolecularBiology.P74.Nov.22-24.Taichung,Taiwan.(*本篇論文榮獲2013台灣生物化學學會口頭發表論文獎第三名). 95.C.H.Zhuang(莊家輝),H.L.Chen,andC.M.Chen*.2012/12Thefunctionalassessmentofkefironthepostponementofbonelossinovariectomizedrats.,Inthe2012ConferenceofTaiwanSocietyforBiochemistryandMolecularBiology..PosterNo.68.pp.106.Dec.6-8,2012,Nantou,Taiwan.. 96.H.L.Chen,Y.W.Lai,andC.M.Chen*.2012/08EpigeneticsilenceofDnaJD1geneinhepatitisBvirusXprotein–positivehepatocellularcarcinoma.InThe2012FASEBSummerResearchConferenceon,“LiverBiology:FundamentalMechanisms&TranslationalApplications.PosterNo.6.Jul.29-Aug.3,2012.SnowmassVillage,CO,USA.. 97.H.L.Chen,C.Y.Chen,andC.M.Chen*.2012/07AChineseherbalmedicine,Gexia-ZhuyuTang(GZT),preventsdimethylnitrosamine-inducedliverfibrosisthroughinhibitionofhepaticstellatecellsproliferation,InThe2012FASEBSummerResearchConferenceon“LiverBiology:FundamentalMechanisms&TranslationalApplications.PosterNo.9.Jul.29-Aug.3,2012.SnowmassVillage,CO,USA.. 98.C.M.Chen*,H.C.Liu,S.Y.Pai,W.T.K.Cheng,andH.L.Chen2012/04OraladministrationoftransgenicDp2peptide-enrichedmilkinducestolerancefromallergicasthma,InThe2012ExperimentalBiologyInternationalMeeting:TranslatingScienceforTomorrow’sHealth.TheFASEBJ.2012;26:LB197.Apr.21-25,2012.SanDiego,CA,USA. 99.Lu-TzuChen(陳律慈),H.L.Chen,andC.M.Chen*.2012NuclearfactorkappaBplaysanimportantroleduringthespermatogenesisdevelopmentoftestis,Inthe2012Asia-PacificDevelopmentBiologyConferencePosterNo.2248.Oct.5-8,2012.Taipei,Taiwan.. 100.W.H.Chang(張雯惠),H.L.Chen,andC.M.Chen*.2012Anti-inflammatoryeffectoflactoferrinonhyperoxia-inducedsystemicinflammatoryresponsesusingNF-κB/luciferasetransgenicmice,Inthe2012Asia-PacificDevelopmentBiologyConference.PosterNo.2080.Oct.5-8,2012.Taipei,Taiwan. 101.C.W.Lai(賴政威),H.L.Chen,andC.M.Chen*2012ThepositioneffectoftransgenicmicecausesEGFPgenderdifferentialexpressioninliver.Inthe2012Asia-PacificDevelopmentBiologyConference,PosterNo.XP-07.Oct.5-8.Taipei,Taiwan. 102.Y.T.Tung,H.L.Chen,H.C.Tsai,S.H.Yang,Y.C.Chang,andC.M.Chen*.2012Therapeuticpotentialofandrographolidefortreatinglungadenocarcinomas,Inthe5thInternationalConferenceonIndustrialBioprocesses.Oct.7-10,2012,Taipei,Taiwan.,pp.356. 103.C.M.Chen*,Y.T.Tung,Y.W.Lai,M.L.Wang,T.C.Tsai,andH.L.Chen.2012Cloningandexpressionofhumanextracellularsuperoxidedismutasegene(EcSOD)infood-gradeLactobacilluscasei,Inthe5thInternationalConferenceonIndustrialBioprocesses.Oct.7-10,2012,Taipei,Taiwan,pp.357. 104.C.J.Shen,W.T.K.Cheng,J.Y.Cheng,H.L.Chen,andC.M.Chen*2012Productionofmultimericmethyl-bindingdomain(MBD)proteinforgenome-widehypermethylatedgenesscreening,Inthe5thInternationalConferenceonIndustrialBioprocesses.Oct.7-10,2012,Taipei,Taiwan,pp.359. 105.W.H.Chang(張雯惠),H.L.Chen,C.C.Yen,andC.M.Chen*2012Anti-inflammatorypathwayoflactoferrinonhyperoxia-inducedlunginflammatoryresponsesusingNF-κB/luciferasetransgenicmice,Inthe2012EleventhAnnualAACRInternationalConferenceonFrontiersinCancerPreventionResearch.PosterNo.270347_1..Oct.16-19,2012,Anaheim,California,USA.,pp.168. 106.Y.T.Tung(童鈺棠),H.L.Chen,andC.M.Chen*2012TanshinoneIattenuateslungtumorigenesisinVEGF-overexpressingtransgenicmiceviainhibitionoftumor-activatedcellcyclepathway,Inthe2012EleventhAnnualAACRInternationalConferenceonFrontiersinCancerPreventionResearch.PosterNo.247589_1..Oct.16-19,2012,Anaheim,California,USA,pp.133. 107.G.J.Wang(王冠傑),H.L.Chen,andC.M.Chen*2012ProductionofrecombinantcaseinphosphopeptidetrimerusingPichiapastoris.Inthe2012ConferenceofTaiwanSocietyforBiochemistryandMolecularBiology.,PosterNo.50.Dec.6-8,2012,Nantou,Taiwan.,pp.88. 108.H.L.Chen,C.C.Yen,Y.W.Lai,C.W.Lai,C.Y.Lin,andC.M.Chen*.2012Aerosolizedhumanextracellularsuperoxidedismutase(hEC-SOD)preventshyperoxia-inducedlunginjury,InThe2012ExperimentalBiologyInternationalMeeting:TranslatingScienceforTomorrow’sHealth.TheFASEBJ.2012;26:LB198.Apr.21-25,2012.SanDiego,CA,USA.. 109.M.C.Chen,C.Y.Huang,C.T.Ku,H.Lin,andC.M.Chen*2011/09TheRoleofP25/Cdk5inRetinoicAcid-TriggeredApoptosisofProstateCancerCells,InThe7thFAOPSCongress.Taipei,Taiwan.Sep11-14,2011.(oral#O5-05). 110.M.C.Chen,C.M.Chen*,andH.Lin*.2011Cyclin-DependentKinase5RegulatesAndrogenProductioninMouseOvaryThecalCells,ProgramandAbstractofthe40thAnnualMeetingoftheSocietyfortheStudyofReproduction(poster#708).July31-August4,2011.Portland,USA.. 111.J.Y.Sun(孫正岳),H.L.Chen,andC.M.Chen*2011EstablishmentofantihypertensivepeptideexpressedintransgenicmicemammarysystemandrecombinantPichiapastorisyeast,InThe2011TaiwanSocietyforBiochemistryandMolecularBiology.PosterNo.P3..Nov.24-25,2011.PeikongCreek,Nantou,Taiwan.. 112.C.L.Tsai(蔡至倫),H.L.Chen,andC.M.Chen*.2011FermentedmilkimprovesleptindeletionOB/OBmiceinducednon-alcoholicfattyliverdiseasebydecreasinglipogenesisgenesexpression,InThe2011TaiwanSocietyforBiochemistryandMolecularBiologyPosterNo.P50..Nov.24-25,2011.PeikongCreek,Nantou,Taiwan.. 113.Y.T.Tung,H.L.Chen,T.C.Tsai,C.W.Lai,C.J.Shen,Y.W.Lai,andC.M.Chen*.2011Curcuminreducespulmonarytumorigenesisinvascularendothelialgrowthfactor,InAnnualMeetingofthe102thAmericanAssociationforCancerResearch(AACR).No.2380.Apri2-6,Orlando,USA.. 114.H.L.Chen,C.W.Lai,C.J.Shen,Y.W.Lai,andC.M.Chen*2011CurcuminreducespulmonarytumorigenesisviainhibitionofvascularendothelialgrowthfactorA165(VEGF-A165)inlungadenocarcinomacells,In19thAnnualInternationalConferenceonIntelligentSystemsforMolecularBiology(ISMB).No.C11..July15-19,Vienna,Austria.. 115.Y.W.Lai,H.L.Chen,J.J.W.ChenandC.M.Chen*.2011Theeffectsofmethylation-controlledDnaJD1inhepatitisBvirusXproteinexpressedhepatocellularcarcinoma.InAnnualMeetingofthe102thAmericanAssociationforCancerResearch(AACR).NO.2416.Apri2-6,Orlando,USA. 116.C.M.Chen*,T.C.Tsai,W.Lin,S.H.Yang,W.T.K.Cheng,E.H.Cheng,M.S.Lee,andK.Y.Chong2011GranzymeG,aserineprotease,isexpressedinthetwo-cellstagemouseembryothatrequiredforMZT,.In19thAnnualInternationalConferenceonIntelligentSystemsforMolecularBiology(ISMB).No.C11.July15-19.Vienna,Austria. 117.J.Y.Chen,H.J.Lin,H.L.ChenandC.M.Chen*2011HepatoprotectiveandantihepatofibrooticeffectsofYiGuanJianinratswithdimethylnitrosamine-inducedliverfibrosis,InThe46thAnnualMeetingoftheEuropeanAssociation(EASL)..March30–April3,Berlin,Germany,pp.241. 118.C.W.Lai,K.Y.Lin,F.J.Liou,H.L.Chen,J.C.ChengandC.M.Chen*.2011FTSJ2,aputativeribosomalRNAmethyltransferase,suppressedcellinvasionandmigrationincancercellline,InAnnualMeetingofthe102thAmericanAssociationforCancerResearch(AACR).No.3877.Apri2-6,Orlando,USA. 119.M.T.Wu(吳敏翠),Y.J.Chen,H.L.ChenandC.M.Chen*.2011Thetumorsuppressorfunctionalstudiesofprotocadherin19(PCDH19)geneinhepatomacelllines,Inthe2011JoinedMedicalOncologyConference.A1-37.Apr30-May1,Taipei,Taiwan.. 120..J.Shen(沈志傑),J.Cheng,E.H.Hsieh,H.L.ChenandC.M.Chen*.2011Methyl-bindingdomainproteinapplicationsforhypermethylatedgenesidentificationinclonedporcineandcancercells,Inthe44thAnnualMeetingfortheJapaneseSocietyofDevelopmentalBiology.P1183.May17-21,Okinawa,Japan. 121.T.C.Tsai(蔡東州),W.Lin,S.H.Yang,W.T.K.Cheng,E.H.Cheng,M.S.Lee,K.Y.ChongandC.M.Chen*.2011GranzymeGisexpressedinthetwo-cellstagemouseembryoandisrequiredforthematernal-zygotictransition,Inthe44thAnnualMeetingfortheJapaneseSocietyofDevelopmentalBiology.May17-21,Okinawa,Japan,pp.1183. 122.C.M.Chen*2010Newstrategyofpharmaceuticalproteinproductionsbythemilksoftransgenicclonedanimals,In2010NewAppoachesofTargetedDrugMedicalTherapyConference.Mar.24-25.KaohsiungMedicalUniversity,Taiwan.(Invitedspeaker). 123.I.A.Chen,F.C.Liu,H.L.Chen,andC.M.Chen*2010AdministrationofrecombinantmyostatinpropeptidepromotesmyogensisofC2C12myoblastcells.InProc,ofthe25thJointAnnualConferenceofBiomedicalSciences.P689.Mar.27-28,NDU,Taipei,Taiwan.. 124.T.H.Hung,C.J.Shen,C.M.Chen,andK.Y.Chong2010MethylationprofilingofCpGislandsinmultipledrugresistantcellline,InAnnualMeetingofthe101thAmericanAssociationforCancerResearch(AACR).P4914..WashingtonDC,USA.. 125.T.H.Hung,C.P.Tseng,N.Sakamoto,C.M.Chen,andJ.C.Cheng2010Theinteractionofnon-structureproteinNS5BandlipogenicenzymemodulateshepatitisCvirusreplication,Inthe7thInternationalMeetingonHepatitisCVirusandRelatedViruses(HCV2010).P-125.PacificoYokohama,Japan. 126.C.J.Shen,C.C.Lin,P.C.Shen,W.T.K.Cheng,H.L.Chen,andC.M.Chen*.2010Dissectingsatelliteandimprintinggenesmethylationstatusinclonedbovine,Aberrantmethylationinimprintingloci.InAnnualMeetingofthe101thAmericanAssociationforCancerResearch(AACR).P173.Apr.18-22,WashingtonDC,USA.. 127.H.L.Chen,C.J.Shen,andC.M.Chen*.2010Differentialepigeneticchangespresentinginimprintedgenesofclonedswinegenomes,2010LorneGenomicsInternationalConference.Feb.12-17.Lorne,Melbourne,Australia. 128.C.M.Chen*,C.J.Shen,S.C.Wu,W.T.K.Cheng,andH.L.Chen.2010OPNpromotercontrolledbyDNAmethylation:Aberrantmethylationinclonedporcinegenome,In2010LorneGenomicsInternationalConference.Feb.12-17.Lorne,Melbourne,Australia. 129.Y.H.Chang,C.L.Liu,H.L.Chen,andC.M.Chen*.2010Exon-skippedCanislactoferrinexhibitsantimicrobialactivityandgrowthinhibitionoflungcarcinomacell,InProc.ofthe15thTaiwanJointCancerConference:MolecularOncology-PushingCancerManagement,Astepforward.A1-56.May2-3,NDU,Taipei,Taiwan. 130..Y.W.Lai,H.L.Chen,M.F.Tsai,andC.M.Chen*.2010Characterizationofmethylation-controlledDnaJD1inHep3Bhepatomacellline,InAnnualMeetingofthe101thAmericanAssociationforCancerResearch(AACR).P174.Apr.18-22,WashingtonDC,USA. 131.Z.X.Yang,H.L.Chen,andC.M.Chen*.2010Establishmentofhyperoxia-inducedacutelunginjury(ALI)mousemodelandassessmentofaerosolizedEC-SODtoprotectlunginjury,InXIthChineseExperimentalAnimalSocietyAnnualConference.A16.Nov.2010.Taipei,Taiwan. 132.Y.C.Chang,H.L.Chen,Y.J.Chen,andC.M.Chen.2009/05CharacterizationofBdomain-deletedrecombinanthumanfactorVIIIintransgenicpigs,InProc.ofthe14thTaiwanJointCancerConferenceMolecularOncology-PushingCancerManagement,Astepforward.A1-19.May2-3,NDU,Taipei,Taiwan.. 133.S.R.Fan,Y.W.Lai,C.F.Lin,N.W.Chang,M.H.Tsai,C.M.Chen,andJ.C.Cheng2009IdentifyingDNAmethylationstatusinoralcancersusingCpGislandsmicroarray,InProc.ofthe14thTaiwanJointCancerConference:MolecularOncology-PushingCancerManagement,Astepforward.A1-56.May2-3,NDU,Taipei,Taiwan. 134.C.C.Lin,P.C.Shen,W.T.K.Cheng,C.J.Shen,andC.M.Chen2009Epigeneticaberrationofimprintinggenesinsomaticnucleartransferredcloningbovinegenomes,InProc.of2009InternationalSymposiumofStemCellsandBiogengineering.P1-1.May16-17,NCKUMedicalCollege,Tainan,Taiwan.(*本篇論文榮獲第五屆台灣幹細胞學會2009幹細胞與組織工程國際研討會壁報論文優勝獎). 135.S.T.Wen,C.W.Lai,C.C.Yen,H.L.Chen,andC.M.Chen.2009Identificationofmouseamnioticfluid-derivedstemcellsfromeGFPtransgenicmiceanditsapplicationontherepairsofhyperoxia-inducedlunginjury,InProc.of2009InternationalSymposiumofStemCellsandBiogengineering.P3-3..May16-17,NCKUMedicalCollege,Tainan,Taiwan.(*本篇論文榮獲第五屆台灣幹細胞學會2009幹細胞與組織工程國際研討會壁報論文優勝獎). 136.H.L.Chen,andC.M.Chen.2009Lactoferrin-enrichedMilkreducesneedforantibioticsinanimalfeedandenhancesoffspringgrowthperformance,InChina-TaiwanBiotechInteractionConference.Feb.4-7,2009.FuchouUniversity,China.. 137.C.M.Chen*.2009Theapplicationsofransgeniccloninganimalsinphamarceuticalproteindrugsandsubunitvaccines,InXthChineseExperimentalAnimalSocietyAnnualConference.Nov.26-27,2009.Taipei,Taiwan.(Invitedspeaker). 138.H.L.Chen,C.C.Yen,T.C.Tsai,andC.M.Chen*.2009Recombinantporcinelactoferrinexpressedinthemilkoftransgenicmiceenhancesoffspringgrowthperformance,InIXthInternationalConferenceonLactoferrin.PVIII-2.Oct.18-23,2009.Beijing,China. 139.C.M.Chen*,C.C.Yen,andH.L.Chen.2009Lactoferrinasanaturalregimenofselectivedecontaminationofthedigestivetract,InIXthInternationalConferenceonLactoferrin.PIX-2..Oct.18-23,2009.Beijing,China.. 140.C.M.Chen*,(Invitedspeaker)andH.L.Chen.2009Lactoferrin-enrichedmilkprotectsneonatalfromalethalchallengewithenterovirustype71,InChina-TaiwanBiotechInteractionConference.Feb.4-7,2009.FuchouUniversity,China. 141.C.J.Shen,S.C.Wu,W.T.K.Cheng,H.L.Chen,andC.M.Chen2009OPNpromotercontrolledbyDNAmethylation:Aberrantmethylationinclonedporcine,InAnnualMeetingofthe100thAmericanAssociationforCancerResearch(AACR).P3364.Denver,Colorado,USA. 142.Y.W.Lai,H.L.Chen,J.Chen,andC.M.Chen2009UseofmouseCpGislandsmicroarrayforhigh-throughputanalysisofthehepatocellularcarcinomainHBxproteinoverexpressedtransgenicmice,InAnnualMeetingofthe100thAmericanAssociationforCancerResearch(AACR).P5203.Denver,Colorado,USA.. 143.C.C.Lin,P.C.Shen,W.T.K.Cheng,C.J.Shen,andC.M.Chen2009Theaberrantepigeneticmodificationofimprintinggenesinclonedbovinegenomes,InProc.ofthe24thJointAnnualConferenceofBiomedicalSciences.P559.Mar.21-22,NDU,Taipei,Taiwan. 144.C.J.Shen,S.C.Wu,W.T.K.Cheng,T.C.Tsai,C.C.Chen,H.L.Chen,andC.M.Chen2009Aberrantreprogramminglifecycleofimprintedgenesinclonedporcinegenome,InProc.of2009InternationalSymposiumofStemCellsandBiogengineering.P1-2.May16-17,NCKUMedicalCollege,Tainan,Taiwan. 145.C.M.Chen*.(Invitedspeaker)2008/07PCDH21promoterhypermethylationandgenefunctionstudiesinsporadicbreasttumorsandcancercelllines,In2008TaiwanEpigenomicsSymposium.July,25-26,2008.NCCU,Chia-Yi,Taiwan. 146.Y.C.Hung,C.K.Chou,P.J.Tsai,andC.M.Chen2008InflammatoryroleofNF-kBinhyperoxia-inducedlunginjury,In2008Chinese-TaipeiSocietyofLaboratoryAnimalSciencesAnnealConference.Dec.4-5,2008.Taipei,Taiwan.(*本篇論文榮獲第十屆中華實驗動物學會2008學術研討會壁報論文優勝獎),pp.101. 147..L.Chen,W.E.Chen,Y.W.Lai,andC.M.Chen2008Epigeneticdownregulationofdeath-associatedproteinkinaseinhepatocellularcarcinoma,IntheAACRInternationalSpecialConference:InfectionandCancer–Biology,Therapeutics,andPrevention.B26,pp.40.HongKongAcademyofMedicine,HongKong. 148.C.J.Shen,S.C.Wu,W.T.K.Cheng,T.C.Tsai,C.H.Chen,H.L.Chen,andC.M.Chen2008Dissectingepigeneticchangesofimprintinggenesinclonedporcine,Inthe9thDevelopmentalBiologyConference.Sep.5-6..NationalChungHsingUniversity.O-06.(*本篇論文榮獲第九屆發育生物學研討會口頭發表最佳內容獎). 149.M.F.Lin,M.H.Lee,Y.C.Chen,L.S.Ju,M.Y.Huang,C.J.Chang,C.H.Chen,Y.W.Lai,C.J.Shen,andC.M.Chen2008CpGislandmicroarrayanalysisofgeneexpressioninurothelialcellcarcinoma,2008UrologyMedicalAnnualConference.PD10.Aug.30-31.Fu-JenCatholicUniversity,Taipeicounty,Taiwan.(*本篇論文榮獲2008台灣泌尿科醫學年會最佳海報論文獎). 150.H.L.Chen,C.C.Yen,andC.M.Chen.2008Lactoferrin-enrichedmilkreducesneedforantibioticsinanimalfeedandenhancesoffspringgrowthperformance,InInternationalConferenceof2008Nutrigenomics.17-18March,Paris,France. 151.Y.C.Chou,P.W.Huang,H.C.Ho,H.L.Chen,andC.M.Chen2008MolecularmechanismofpulmonarytumorigenesisinducedbyVEGF-A165overexpressioninthetissueoftransgenicmice,InProc.ofthe23thJointAnnualConferenceofBiomedicalSciences.P697.Mar.29-30,NDU,Taipei,Taiwan.(*本篇論文榮獲第二十三屆生物醫學年會之台灣生物化學及分子生物學學會最佳論文獎). 152.C.M.Chen*,Y.J.Lin,andH.L.Chen.2008Methylationprofilingoffiveselectedgenesonchromosome16inhumanhepatocellularcarcinomas,IntheAACRInternationalSpecialConference:InfectionandCancer–Biology,Therapeutics,andPrevention.B25.Dec.5-7,2008.HongKongAcademyofMedicine,HongKong.,pp.39.. 153.C.M.Chen,H.L.Chen,C.M.Hung,andW.T.K.Cheng2008Lactoferrin-enrichedmilkprotectsneonatalfromalethalchallengewithenterovirustype71,InInternationalConferenceof2008Nutrigenomics.17-18March,Paris,France. 154.J.T.Huang,C.P.Tseng,N.Sakanoto,S.C.Lu,C.M.Chen,andJ.C.Cheng2008AnovelNS5B-interactingproteinmodulateshepatitisCvirusreplication,In15thInternationalSymposiumonHepatitisCVirus&RelatedViruses.P417.October5-9,2008.MarriottRivercenter,SanAntonio,Texas,USA.. 155.S.T.Wen,H.L.Chen,andC.M.Chen2008Identificationofmouseamnioticfluid-derivedstemcellsfromeGFPtransgenicmiceanditsapplicationontherepairsofhyperoxia-inducedlunginjury,4thInternationalConferenceonStemCellResearchandTherapeutics.April17-18.Boston,MA,USA.. 156.C.J.Shen,S.C.Wu,W.T.K.Cheng,T.C.Tsai,H.L.Chen,andC.M.Chen2008Characterizationofepigeneticmethylationchangesoffourimprintinggenesinclonedporcine,4thInternationalConferenceonStemCellResearchandTherapeutics.April17-18.Boston,MA,USA.. 157.K.L.Lin,Y.J.Chen,H.L.Chen,andC.M.Chen.2008AnalysisofepigeneticalternationsinaflatoxinB1treatedlivercelllines,InProcofthe13thTaiwanJointCancerConference:CancerStemCell,MolecularImage.A-I-34.May3-4,NDU,Taipei,Taiwan. 158.J.C.Cheng,J.T.Huang,S.C.Lu,N.Sakamoto,C.M.Chen,C.P.Tseng.2008AnovelHCVNS5B-interactingproteinmodulatesHCVreplication:implicationinHCV-associatedhepatocellularcarcinomadiseaseprogressionandprevention,IntheAACR-InfectionandCancer:Biology,Therapeutics,andPrevention.Dec.5-7,2008.HongKongAcademyofMedicine,HongKong. 159..L.Chen,C.C.Yen,andC.M.Chen*.2007SyntheticPorcineLactoferricinwith20-ResiduePeptideExhibitsAntimicrobialActivityagainstEscherichiacoli,StaphylococcusaureusandCandidaalbicans,InSymposiumofInternationalDevelopmentsinScienceandHealthClaims.9-11May2007,Malta.Europe. 160.K.T.Chiu,C.P.Hsu,andC.M.Chen.2007GenemethylationprofilingoflungcancercellsusingCpGislandsmethylationmicroarray,In15thSymposiumonRecentAdvancesinCellularandMolecularBiology.pp.136.Candin,Taiwan. 161.Y.P.Kuan,H.L.Chen,andC.M.Chen.2007DNAdamageandgeneepigeneticchangesduringhyperoxiainjuryresponsetosupplementoxygentherapies,In15thSymposiumonRecentAdvancesinCellularandMolecularBiology.pp.140.Candin,Taiwan. 162.T.W.Chu,S.C.Wu,andC.M.Chen.2007DiscrepantgreenfluorescenceexpressioninpCX-EGFPtransgenicmiceanditsrelationshipwithpromoterDNAmethylation.,In15thSymposiumonRecentAdvancesinCellularandMolecularBiology.pp.149.Candin,Taiwan. 163.H.Y.Lin,H.L.Chen,S.D.Chen,andC.M.Chen.2007ProtocadheringammaA12(PCDH21),anewcandidatetumor-suppressorgene,itsassociationwithinhibitionofcellmigrationandcellproliferation,In15thSymposiumonRecentAdvancesinCellularandMolecularBiology.pp.151.Candin,Taiwan. 164.C.M.Chen.(Invitedspeaker)2007AberrantDNAmethylationpatternsinthegenomesofcancercellsandcloninganimalusingaCpGislandsmicroarray.Symposium3:CancerandGenomics/Epigenomics,InProc.ofthe22thJointAnnualConferenceofBiomedicalSciences.S10.NDU,Taipei,Taiwan. 165.Y.P.Kuan,H.L.ChenandC.M.Chen.2007DNAdamageandgeneepigeneticchangesduringhyperoxiainjuryresponsetosupplementoxygentherapies,InInternationalConferenceonCellularResponsestoDNADamageandTechnicalWorkshoponDNARepair.pp.17.Hsin-Chu,Taiwan.(*本篇論文榮獲第一屆DNA損傷暨細胞回應國際研討會之論文口頭發表優勝獎). 166.H.L.Chen,C.C.Yen,andC.M.Chen.2007ANewApproachtoProduceHumanExtracellularSuperoxideDismutase(ECSOD)intheMethylotrophicYeastPichiapastoris,InSymposiumofInternationalDevelopmentsinScienceandHealthClaims.9-11May2007,Malta. 167.K.T.Ho,Y.H.Chang,M.Y.Shiau,andC.M.Chen.2006IL-4,IL-10andCTLA-4genepolymorphismsinTaiwanesepatientswithankylosingspodylitis,InProc.ofthe1stInternationalConferenceonOsteoimmunology:InteractionsoftheImmuneandSkeletalSystems.Abs#55.Athens,Greece. 168.G.J.Huang,S.T.Chen,K.T.Yeh,C.M.Chen,andH.L.Chen.20063OST3BpromoteraberrantmethylationanditsclinicopathologicalfeaturesinTaiwanbreastcancertissues,InProc.ofthe21thJointAnnualConferenceofBiomedicalSciences.P505.NDU,Taipei,Taiwan. 169.C.M.Chen.(Invitedspeaker).2006DissectingofepigeneticaberrationinthegenomesofcancerandcloninganimalusingaCpGislandsmicroarray,InProc.oftheInternationalSymposiumonRecentAdvanceofStemCellResearch.Sep.1-2.Pp.16-17.TaipeiMedicalUniversity,Taipei,Taiwan. 170.C.M.Chen,W.E.Chen,Y.W.Lai,J.C.Wu,andH.L.Chen.2006Epigeneticdown-regulationofdeath-associatedproteinkinaseinhepato-cellularcarcinoma,InProc.ofthe12thInternationalSymposiumonViralHepatitisandLiverDisease.Jul.1-5.P433.Paris,France. 171.C.M.Chen*,J.C.Wu,andH.L.Chen.2006DissectingcomplexDNAmethylationchangesinhepatocellularcarcinoma:Anewmicroarraytechniqueforhigh-throughputalternatingepigeneticanalysis,InProc.ofthe1stInternationalSymposiumonHepatocellularCarcinoma.Jul.6-8.PastureInstitute,France. 172.L.P.Chen,D.S.Chao,S.Y.Lin,andC.M.Chen.2006DissectingofDNAmethylationprofilesintumorgenomesofcolorectalcancer,InProc.ofthe11thJointAnnualMeetingofCancerResearch.A-I-19.May6-7,NDU,Taipei,Taiwan. 173.P.W.Huang,H.C.Ho,Y.J.Chen,andC.M.Chen.2006HumanVEGFoverexpressioninlungtissueoftransgenicmiceregulatedbythepromoterofclaracellsecretoryproteingene,InProc.ofthe11thJointAnnualMeetingofCancerResearch.A-I-20.May6-7,NDU,Taipei,Taiwan. 174.W.E.Chen,J.C.Wu,andC.M.Chen.2006Epigeneticdown-regulationofdeath-associatedproteinkinaseinhepatocellularcarcinoma,InProc.ofthe21thJointAnnualConferenceofBiomedicalSciences.P095.NDU,Taipei,Taiwan.(*本篇論文榮獲第二十一屆生物醫學年會之台灣生物化學及分子生物學學會最佳論文獎). 175.J.W.Lai,F.J.Liou,A.L.Hsu,andC.M.Chen.2006MolecularcloningandcharacterizationofporcineFTSJ1andFTSJ2geneswhichhomologoustotheRRMJheatinducedproteininE.coli,InProc.ofthe21thJointAnnualConferenceofBiomedicalSciences.P096.NDU,Taipei,Taiwan. 176.G.J.Huang,H.L.Chen,S.T.Chen,andC.M.Chen.2005PromoterhypermethylationandaberrantmRNAexpressionofheparinsulfateD-glucosaminyl3-O-sulfotransferase(3OST3B)geneinTaiwanbreastcancertissues,In13thSymposiumonRecentAdvancesinCellularandMolecularBiology.pp.55.Candin,Taiwan. 177.J.Y.Huang,C.C.Lin,S.H.Yang,andC.M.Chen.2005ExpressionofEnterovirus71capsidproteinsVP1andVP4intransgenicmilksregulatedbyalpha-lactalbuminpromoterandcaseinleadersequences,In13thSymposiumonRecentAdvancesinCellularandMolecularBiology.pp.107.Candin,Taiwan. 178.C.J.Shen,S.C.Wu,W.T.K.Cheng,andC.M.Chen.2005Theaberrantepigeneticmodificationofimprintinggenesinclonedsowgenomes,In13thSymposiumonRecentAdvancesinCellularandMolecularBiology.pp.108.Candin,Taiwan. 179.W.C.Huang,C.C.Lin,andC.M.Chen.2005Functionalanalysisofanovelidentifiedextracellularlactase-phlorizinhydrolase(EC-LPH)genefromhumansmallintestine,InProc.ofthe20thJointAnnualConferenceofBiomedicalSciences.pp.302.Taipei,Taiwan.(*本篇論文榮獲第二十屆生物醫學年會之中華民國細胞與分子生物學會優秀看板論文獎). 180.C.Y.Lin,C.C.Yen,andC.M.Chen.2005Bacterialtoxicitychallengesstudyintransgenicmiceharboringbiologicallyactivelactoferrin,InProc.ofthe20thJointAnnualConferenceofBiomedicalSciences.pp.325.Taipei,Taiwan. 181.P.C.Yu,G.C.Chang,andC.M.Chen.2005DissectingDNAmethylationcharacteristicsindifferentchemo-sensitivityofIRESSA-treatedlungcancers,InProc.ofthe20thJointAnnualConferenceofBiomedicalSciences.pp.438.Taipei,Taiwan. 182.M.Y.Chiang,S.T.Chen,andC.M.Chen.2005Promoterhypermethylationandlossofexpressionoftheprotocadherin(PCDH21)geneinTaiwansporadicbreasttumors,InProc.ofthe20thJointAnnualConferenceofBiomedicalSciences.pp.442.Taipei,Taiwan. 183.C.M.Chen*,Y.J.Lin,andJ.C.Wu.2005Methylationprofilingoffivetumorsuppressorgenesonchromosome16inhumanhepatocellularcarcinomacells,Inthe41stAnnualMeetingofLiverCancerStudyGroupofJapan.Chiba,Tokyo.(*本篇論文榮獲日本肝癌學會SelectedPosterPresentationAward). 184.P.I.Chen,T.A.Yu,H.L.Chen,C.M.Chen,andC.H.Chiang.2005Expressionandcharacterizationofhumansuperoxidedismutasegeneintomatoplants.AnnualMeetingofPlantPathologyBulletin,,Taichung,Taiwan.. 185.Y.W.Lai,H.L.Chen,C.W.Lin,andC.M.Chen.2004Productionofrecombinantporcinelactoferrininmethylotrophicyeastandcharacterizationofitsglycosylationpatternandantibacterialactivity,In12thSymposiumonRecentAdvancesinCellularandMolecularBiology.pp.108.Candin,Taiwan. 186.M.L.Wang,C.M.Chen,T.C.Tsai,andH.L.Chen.2004Cloningandexpressionofhumanextracellularsuperoxidedismutase(ecSOD)geneinLactobacilluscasei,InProc.Ofthe19thJointAnnualConferenceofBiomedicalSciences.pp.207.Taipei,Taiwan. 187.Y.P.Chen,C.M.Chen,H.L.Chen,andC.W.Lin.2004AngiotensinconvertingenzymeinhibitoryactivityofKefirfermentationproductswithantihypertensionpeptides,pp.94.InProc.ofthe11thAsian-AustralasianAssoc.AnimalProductionCongress.KualaLumpur,Malaysia. 188.T.C.Tsai,S.H.Yang,andC.M.Chen.2004Thestudyofaberrantepigeneticmodificationinclonedmice,InProc.ofthe11thAsian-AustralasianAssoc.AnimalProductionCongress.pp.75.KualaLumpur,Malaysia. 189.Y.W.Lai,S.H.Yang,H.L.Chen,C.W.Lin,andC.M.Chen.2004ProductionofrecombinantporcinelactoferrinwithbactericidalactivityinPichiapastoris,InProc.ofthe11thAsian-AustralasianAssoc.AnimalProductionCongress.pp.87.KualaLumpur,Malaysia. 190.Y.P.Chen,C.M.Chen,H.L.Chen,andC.W.Lin.2004AngiotensinconvertingenzymeinhibitoryactivityofKefirfermentationproductswithantihypertensionpeptides,InProc.ofthe11thAsian-AustralasianAssoc.AnimalProductionCongress.pp.94.KualaLumpur,Malaysia. 191.C.M.Chen.2004EstablishmentofmouseCpGislandsmicroarrayanditsapplicationonstemcelldifferentiation,June,24th,InvitedSpeaking,WesternGeneralHospital,SchoolofMolecularandClinicalMedicine,UniversityofEdinburgh.Scotland,UK. 192.F.C.Liu,A.L.Hsu,andC.M.Chen.2004MyostatincDNAcloningandsequencinginTLRINo.1blackpig,J.Chin.Soc.Anim.Sci.33(suppl.):140. 193.C.M.Hung,H.C.Huang,H.L.Liu,T.F.Chen,Y.S.Cheng,C.W.Liao,H.L.Chen,andC.M.Chen.2004Effectofdietarysupplementinglactoferrinonthegrowthperformanceofbroilers,J.Chin.Soc.Anim.Sci.33(suppl.):236. 194.M.L.Wang,C.M.Chen,T.C.Tsai,andH.L.Chen.2004Expressionofhumanextracellularsuperoxidedismutasegeneinlactobacilluscaseiandcharacterizationofitsantioxidativeactivity,J.Chin.Soc.Anim.Sci.33(suppl.):289.(*本篇論文獲得93年度壁報展示最佳論文獎). 195.T.C.Tsai,H.L.Chen,andC.M.Chen.2003AnovelmethylationCpGislandmicroarray-basedscreeningofpotentialhumanimprintinggenes,InProc.Ofthe18thJointAnnualConferenceofBiomedicalSciences.pp.30.Taipei,Taiwan.(*本篇論文榮獲第十八屆生物醫學年會之台灣生物化學及分子生物學學會最佳論文獎). 196.Y.J.Lin,J.C.Wu,andC.M.Chen.2003Methylationstatusofmultipletumorsuppressorgenesinhepatomacanceranditsrelationshipwithclinicalpathology,InProc.Ofthe18thJointAnnualConferenceofBiomedicalSciences.pp.60.Taipei,Taiwan. 197.C.M.Chen,H.L.Chen,andTimH.M.Huang.2003LossofexpressionandaberrantpromotermethylationofthePCDH21(protocadherin)geneinhepatomaandbreasttumors,InAnnualMeetingofthe94thAmericanAssociationforCancerResearch.Toronto,Ontario,Canada. 198.Y.P.Chen,C.M.Chen,H.L.Chen,andC.W.Lin.2003AngiotensinconvertingenzymeinhibitoryactivityofKefirfermentationproducts,J.Chin.Soc.Anim.Sci.32(4):249. 199.C.M.Chen,H.L.Chen,andTimH.M.Huang.2003AberrantpromoterhypermethylationoftheProtocadheringammaA12geneinbreasttumors,InAACRSpecialConferenceofAdvancesinBreastCancerResearch:Genetics,BiologyandClinicalApplications.HuntingtonBeach,California,USA. 200.H.L.Chen,C.M.Chen,andTimH.M.Huang.2003Methylationtargetarrayforhigh-throughputanalysisofpromoterhypermethylationinmultiplebreasttumors,InAACRSpecialConferenceofAdvancesinBreastCancerResearch:Genetics,BiologyandClinicalApplications.HuntingtonBeach,California,USA. 201.Wu,S.C.,C.M.Chen,Jangwon.Lee,S.P.Lin,K.B.Choo,C.N.Weng,P.C.Yang,C.F.Tu,X.Yang,W.T.K.Cheng.2002Generationofdouble-genestransgenicpigsandtheircloning,InternationalSymposiumonAgriculturalBiotechnology(ISAB).PP.64-65(www.sinica.edu.tw/-npagrbt/isab/). 202.Wu,S.C.,C.J.Lin,C.F.Tu,S.P.Lin,S.R.Wang,C.H.Mao,C.M.Chen,K.BChoo,W.T.K.Cheng.2002RecentadvancesinstudiesrelatedtogenerationoftransgenicfarmanimalsinTaiwan,InternationalSymposiumonAgriculturalBiotechnology(ISAB).PP.59-61(www.sinica.edu.tw/-npagrbt/isab/). 203.P.S.Yan,A.Weinmann,H.Shi,S.H.Wei,F.J.Rodriguez,F.Rahmatpanah,H.LChen,C.M.Chen,A.Waha,T.Efferth,F.Rodel,P.Goodfellow,B.Brown,P.Farnham,andT.H.-M.Huang.2002IdentificationofE2Ftargetpromotersfrequentlyhypermethylatedinsolidtumors,InAnnualMeetingofthe93thAmericanAssociationforCancerResearch.SanFrancisco,California,USA. 204.C.M.Chen,H.L.Chen,P.S.Yan,andT.H.-M.Huang.2002Methylation“tissue”array:anoveltechniqueforsimultaneousanalysisofextensiveDNAhypermethylationinmultiplebreasttumors,InAnnualMeetingofthe93thAmericanAssociationforCancerResearch.SanFrancisco,California,USA. 205.C.M.Chen.2002DevelopmentofmethylationCpGislandMicroarrayanditsapplicationondissectingcomplexepigeneticalternationsincancers.AnnunalconferenceofChineseVeterinaryMedicineanAinalScienceSociety,VeteransGeneralHospital,InvitedSpeakerforSpecialLecture.pp.1.NationalChungHsingUniversity,Taichung,Taiwan. 206.C.M.Chen,H.L.Chen,H.Shi,C.W.Caldwell,G.J.R.Brock,P.S.Yan,andT.H.M.Huang.2002ComplexpatternsofDNAmethylationincancer,IntheCNIOCancerConference,CancerEpigenetics:DNAmethylationandchromatin.pp43-44.Madrid,Spanish. 207.W.T.K.Cheng,andC.M.Chen.2002ResearchrelatedtogenerationoftransgenicanimalinTaiwan,The6thAPECBiotechnologyWorkshop,ATCWGinTaipei.Aug.26–Sep.4,Taiwan. 208.C.J.Lin,C.M.Chen,andW.T.K.Cheng.2002Generationandanalysisoftransgenicmiceanddiarygoatharboringthealpha-LA-hFVIIIgene,J.Chin.Soc.Anim.Sci.31(4):137.(*本篇論文獲得壁報展示最佳論文獎). 209.C.H.Yu,C.M.Chen,andC.W.Lin.2002Genecloningofbovinelactoferricinantibacterialpeptideinmethyltropicyeast,PichiaPastoris,J.Chin.Soc.Anim.Sci.30(4):300.(*本篇論文獲得91年度壁報展示論文新人獎). 210.C.C.Lin,Y.C.Lin,F.Y.Chou,W.T.K.Cheng,andC.M.Chen.2001Humanlactase-phlorizinhydrolase-I(hLPH-1)genecloningandLA-hLPHtransgenicmiceproduction,InProc.Ofthe16thJointAnnualConferenceofBiomedicalSciences.pp.93.Taipei,Taiwan. 211.Chen,CM,Shinn-ChihWu,Chin-FuTu,Shu-WhaLin,Shau-PingLin,Kong-BungChoo,andWTKCheng.2001CurrentstatusandprospectsofresearchstudiesendeavoredtogenerationoftransgenicfarmanimalsinTaiwan,In:Proc.ofthe2ndInternationalSymposiumonBiotechnology.GroundHotel,Taipei,Taiwan. 212.S.Y.Bai,W.T.K.Cheng,andC.M.Chen.2001Generationoftransgenicmicecarryingdustallergengenes,DerpIIandDerpV,fordesensitivitytherapy,InProc.Ofthe16thJointAnnualConferenceofBiomedicalSciences.pp.87.Taipei,Taiwan. 213.C.Y.Lu,C.M.Chen,andC.W.Lin.2001DevelopmentofkefirgrainwithLactobacillitransformantcarryinghumanlactoferringene,J.Chin.Soc.Anim.Sci.30(4):259.(*本篇論文獲得90年度壁報展示最佳論文獎). 214.S.C.Liu,C.M.Chen,andY.H.Hu.2001exidentificationofduckembryobyusingpolymerasechainreaction,J.Chin.Soc.Anim.Sci.30(4):127. 215.Lin,C.J.,C.H.Wang,C.M.Chen,S.W.Lin,S.C.Wu,andW.T.K.Cheng.2001GenerationandanalysisoftransgenicgoatsharboringthecDNAofhumancoagulationfactorVIIIgene.In:Lifesciencesresearchandindustrializationinthe21stcentury,The5thBiotechnol.Symp.Associat.EastAsianRes.Univer.Hsanghai,China. 216.TimHuangandC.M.Chen.2001DissectingcomplexepigeneticalterationsincancerusingCpGislandmicroarray,InTrans-HHSWorkshop:Diet,DNAmethylationProcessesandHealthNatcherConferenceCenter.Aug.6-8.NIHMainCampus,WashingtonDC.USA. 217.P.S.Yan,C.M.Chen,H.Shi,F.Rahmatpanah,S.H.Wei,C.W.CaldwellandTimHuang.2001DissectingcomplexepigeneticalterationsinbreasttumorsusingCpGislandmicroarray,IntheSecondAnnualNorthwestMicroarrayConference.pp15.UniversityofWashington,SeattleWA,USA. 218.SusanH.Wei,C.M.Chen,H.Shi,P.S.Yan,J.Harnsomburana,C.R.Shyu,K.P.Nephew,R.Brown,andTimH.-M.Huang.2001MethylationMicroarrayAnalysisofLateStageOvarianCarcinomasDistinguishesDisease-FreeSurvivalinPatients,IntheAACRconference,CancerandChromosomalOrganization/EpigeneticsofCancer.ppA-20.PalmDesert,California,USA.(*本篇論文獲得美國癌症醫學會之年度最佳論文獎). 219.G.J.R.Brock,C.M.Chen,T.H.M.HuangandK.J.Johnson.2001AnoveltechniquefortheidentificationofCpGislandsexhibitingalteredmethylationpatterns(ICE-AMP),IntheAACRconference,CancerandChromosomalOrganization/EpigeneticsofCancer.ppA-19.PalmDesert,California,USA. 220.H.Shi,P.S.Yan,C.M.Chen,F.Rahmatpanah,C.Lofton-Day,C.W.Caldwell,andT.H.M.Huang.2001ExpressedCpGislandsequencetagmicroarraysfordualscreeningofDNAhypermethylationandgenesilencingincancercells,InAnnualMeetingofthe93thAmericanAssociationforCancerResearch.SanFrancisco,California,USA. 221.S.H.Wei,C.M.Chen,H.Shi,P.S.Yan,J.Harnsomburana,C.R.Shyu,F.Rahmatpanah,K.P.Nephew,G.Strathdee,R.Brown,andT.H.M.Huang.2001Identificationofmethylationmarkersfordistinguishingprogression-freesurvivalinlatestageovariancancerthroughCpGislandmicroarray,InAnnualMeetingofthe93thAmericanAssociationforCancerResearch.SanFrancisco,California,USA. 222.C.M.Chen,Y.C.Chang,H.L.Chen,andW.T.K.Cheng.2000Large-scaleproductionandcharacterizationofporcinegrowthhormoneinmethyltropicrecombinantyeast,InProc.ofthe9thAsian-AustralasianAssoc.AnimalProductionCongress.UniversityofNewSouthWales,Sydney,Australia. 223.J.C.Wu,andC.M.Chen.1999HumanandswinehepatitisEvirusinfectioninTaiwan,In1999AnnunalconferenceofChineseMedicineSociety.VeteransGeneralHospital,p40-41.Taipei,Taiwan. 224.C.J.Lin,W.T.K.Cheng,C.M.Chen,W.T.Lien,andS.C.Wu.1999Competenceofmousefetaldevelopmentinvivoandforeigngeneintegratedefficiencyafterpronuclearmicroinjection,J.Chin.Soc.Anim.Sci.28(suppl.):114. 225.Y.C.Lin,C.M.Chen,andC.W.Lin.1999GenecloningandexpressionoflactoferrininmethyltropicyeastPichiapastoris,J.Chin.Soc.Anim.Sci.29(suppl.):260.(*本篇論文獲得壁報展示論文新人獎). 226.Y.C.Tsai,W.T.K.Cheng,K.B.Choo,C.M.Chen,W.T.Lien,andS.C.Wu.1999ExpressionofhumanfactorIXinserumoMT-hFIXtransgenicmice,J.Chin.Soc.Anim.Sci.28(suppl.):158. 227.C.M.Chen.1998Sex-specificsequencesidentifiedfrombovineX-Yhomologousamelogeningeneandtheapplicationofthesesequencesforsex-determinationofcowembryos,Invitedspeaker,ChanghuaChristianHospital,Changhua,Taiwan,ROC. 228.S.C.Wu,C.M.Chen,S.P.Lin,K.B.Choo,andW.T.K.Cheng.1998ProductionoftransgenicmiceandpigletsusingthehumanIXfactorcDNAclones,In2ndAssociationofEastAsianResearchUniversities.p34-35.Taipei,Taiwan. 229..Wu,S.C.,S.P.Lin,C.M.Mao,S.R.Wang,C.M.Chen,M.C.Huang,T.T.Hsu,T.S.Yang,K.H.Lee,R.Chu,K.B.ChooandW.T.K.Cheng.1998ProductionoftransgenicmiceandpigletsusingtheporcinelactoferrincDNAandthehumanIXfactorcDNAclones,Proc.Symp.TransgenicAnimals.pp.6-7.PigResearchInstituteTaiwan. 230.S.C.Wu,C.H.Mao,C.M.Chen,M.C.Huang,L.M.Chu,andW.T.K.Cheng.1997Thestudyof-lactoalbumin-porcinelactoferrinfusiongeneinporcineandmouseembryos,J.Chin.Soc.Anim.Sci.26(suppl.):76. 231.W.T.K.Cheng,andC.M.Chen.1997Theapplicationofembryonicsexinginpreimplantationblasotocystdiagnosis,InProc.ofXIIAsianPacificFederationConferenceInternationalCollegeofSurgeons.TaipeiInternationalConferenceCenter,Taipei,Taiwan,ROC. 232.S.C.Wu,C.M.Chen,C.H.Mao,S.L.Wang,H.K.Wu,L.M.Chu,andW.T.K.Cheng.1996Thestudyoftransgenicmicecarryingporcinelactoferringene,J.Chin.Soc.Anim.Sci.25(suppl.):70. 233.S.P.Lin,S.C.Wu,C.M.Chen,C.H.YaiandW.T.K.Cheng.1996ConstructionandexpressionofalphalactoalbuminregulatoryandhumanclottingfactorIXhybridgene,J.Chin.Soc.Anim.Sci.25(suppl.):63.. 234.C.M.Chen,W.T.K.Cheng,andK.B.Choo.1994Analysisoftransgenicmice:Evidenceforfrequentdeletionsandsequenceaberrations,InProc.ofthe7thAAAPAnimalScienceCongress.Vol.IIIp.15-18.Bali,Indonesia. 235.K.B.Choo,andC.M.Chen.1994Cellulargenesandsequencesdisruptedbyhumanpapillomavirusintegrationincervicalcancer,InProc.ofthe3thInternationalCongressofGeneTherapy.Keystone,USA. 236.C.M.Chen,M.P.Shyu,W.T.K.Cheng,andK.B.Choo.1994DirectsequenceanalysisofintegratedHPV16-disruptedcellularsequenceincervicalcancers,InProc.ofthe9thJointAnnualConferenceofBiomedicalSciences.pp.39.CollegeofMedicine,NTU,Taipei,Taiwan. 237.C.M.Chen,W.T.K.Cheng,andK.B.Choo1993Analysisofthehumanpapillomavirustransgenestructureintransgenicmice,InProc.ofthe9thInternationalCongressofVirology.Vol.IPapillomavirus,pp.166.Glasgrow,Scotland,UK. 238.K.B.Choo,C.H.Chen,M.P.Shyu,andW.T.K.Cheng.1993PapidmappingofHPVintegrationincervicalcancerbiopsiesbyPCRprimerwalking,InProc.ofthe9thInternationalCongressofVirology.Vol.IW35celltransformation,pp.62.Glasgrow,Scotland,UK. C.專書  1.Y.W.Lan,C.M.Chen,andK.Y.Chong.2020InvitromethodstoevaluatetheeffectsofmesenchymalstemcellsonTGF-β1-inducedpulmonaryfibrosis.,In:InvitroModelsforStemCellTherapy:MethodsandProtocols.SpringerPublisher,Cambridge,MA,USA.ChapterX.(inpress). E.技術報告  1.C.M.Chen2005ProductionofrecombinanthumanFVIIItherapeuticproteinbyanimalbiotechnologyanditsapplicatioAgricultureBiotechnology.(ROC).3:21-27.(GPN2009305478). 2.C.M.Chen*,andH.L.Chen2005ThedevelopmentofCpGislandsmicroarraytechniqueanditsapplicationsonembryogenesisandtumorgenesis.LifeSci.Newsletter,NSC(ROC). 3.C.M.Chen2004TransgenicDNAdeterminationbyPCRscreeningandslotblotquantitativehybridization.In:TransgenicAnimalTechnologyandProtocol.M.C.Huang.MinistryofEducationPress,Taiwan(ROC).Pp.335-340.(ISBN957-01-7605-9. 4.C.M.Chen2004Theresearchanddevelopmentoftransgenicanimalbiotechnologyinbiomedicalsciences.In:TheDevelopmentofAnimalBiotechnologyIndustry.PungTungAgriculturalBiotechnologyParkCouncilofAgriculture,ExecutiveYuanPress,Taiwan(ROC).Pp.2. 5.C.M.Chen2004Therecombinationmechanismofconcatamerizationandintegrationofexogenousgenesinthechromosomeoftransgenicanimals.In:TransgenicAnimalTechnologyandProtocol.M.C.Huang.MinistryofEducationPress,Taiwan(ROC).Pp.189-200.(ISBN95. 6.C.M.Chen2004TheprotocolfortransgenicDNApurificationandquantification.In:TransgenicAnimalTechnologyandProtocol.M.C.Huang.MinistryofEducationPress,Taiwan(ROC).Pp.297-302.(ISBN957-01-7605-9. 7.S.H.Wei,T.C.Yip,C.M.Chen,andT.H.M.Huang2003IdentifyingclinicopathologicalassociationofDNAhypermethylationincancersusingCpGislandmicroarrays.In:DNAMethylationandCancerTherapy.MosheSzyf,McGillUniversityPress.Montreal,Quebec,Canada.Pp.1-11.(ISBN1417574585. 8.C.M.Chen2003Thedevelopmentandapplicationoftransgenicanimalsystemsinbiopharmaceuticals.BiotechTaiwan(ROC).Vol.1:16-. 9.C.M.Chen*andH.L.Chen2003Applicationsofmethylatedgenemicroarrayonbiologyresearch.In:ResearchTechnologytoAdiopocyteBiology.S.T.DingandW.T.K.Cheng.NationalLibraryPress,TaiwanPp.124-130.(ISBN957-01-5467-5). 10.C.M.Chen*,andH.D.Yen2000ThereportofanimalsciencecongressintheAsian-Australasianassociationofanimalproductionsocieties.Natl.Sci.Coun.Monthly(ROC)28:982-985.(ISSN0250-1651). 11.C.M.Chen,W.T.K.Cheng,C.C.Chang,T.L.Weng,Y.N.Jiang,andJ.T.Hsu1999CaprahircusXchromosomeamelogenin(gAML-X)mRNA,completecds.,752basepairs.Accessionnumber:AF21589. 12.C.M.Chen*,C.C.Chang,T.L.Weng,andW.T.K.Cheng1999CaprahircusamelogeningenelocatedonYchromosome(gAML-Y),completeintron5sequence,1780basepairsAccessionnumber:AF21588. 13.C.M.Chen*,C.C.Chang,T.L.Weng,andW.T.K.Cheng1999CaprahircusamelogeningenelocatedonXchromosome(gAML-X),completeintron5sequence,1577basepairs.Accessionnumber:AF21588. 14.C.M.Chen,W.T.K.Cheng,C.C.Chang,T.L.Weng,Y.N.Jiang,andJ.T.Hsu1999CaprahircusYchromosomeamelogenin(gAML-Y)mRNA,completecds.,746basepairs.Accessionnumber:AF21588. 15.C.M.Chen*,C.L.Hu,andW.T.K.Cheng1999techniquesofbovineembryosexing.Natl.Sci.Coun.Monthly(ROC)27:381-392.(ISSN0250-1651. 16.W.T.K.Cheng,C.M.Chen,C.L.Hu,C.H.Wang,andK.B.Choo1996BostauruschromosomeYamelogenin(AMLY)gene,completeintron5sequences,1539basepairs.Accessionnumber:L4860. 17.W.T.K.Cheng,C.M.Chen,C.L.Hu,C.H.Wang,andK.B.Choo1996BostauruschromosomeXamelogenin(AMLX)gene,completeintron5sequences,1684basepairs.Accessionnumber:L4860. 18.C.M.Chen*,W.T.K.Cheng,andK.B.Choo1995HomosapiensPID-2gene,chromosomerecombinationsite,papillomavirusintegration-disruptedcellularlocus.Accessionnumber:L4299. 19.C.M.Chen*,W.T.K.Cheng,andK.B.Choo1995HomosapiensPID-3gene,chromosomerecombinationsite,papillomavirusintegration-disruptedcellularlocus.Accessionnumber:L4230. 20.C.M.Chen*,W.T.K.Cheng,andK.B.Choo1995HomosapiensPID-1gene,chromosomerecombinationsite,derivedfromCaSkicellline.Accessionnumber:L4299. 21.C.M.Chen1994Majorhistocompatibilitycomplexanditsroleinpoultryproductions.World'spoultryScienceAssoc.(ROC)19:22-3. F.專利  1.C.M.Chen,andH.L.Chen2020/11-2038/11.Methodfortreatingor/andpreventingcalciumdeficiency-relateddiseases.USAPatent,NO.US10,829,517B2. 2.H.L.Chen,C.M.Chen2010-2029NovelAntihypertensivePeptideAndUseThereof.USAPatent,No.7,763,281B2. 3.C.M.Chen*,andH.L.Chen2008NovelEnterovirustype71capsidproteinVP1(EV71-VP1)geneanditsproductionmethod.USAPatent,,No.US-2010-0125918-A1. 4.C.M.Chen*,andH.L.Chen2008NovelEnterovirustype71capsidproteinVP1(EV71-VP1)geneanditsproductionmethod.TaiwanPatent,,No.097139140;pending. 5.C.M.Chen,H.L.ChenandC.C.Huang2008NovelMerBenzymeactasapotentialantidoteagainstmethylmercurytoxicityexpressedintransgenicmilks.TaiwanPatent,No.097141690. 6.S.C.Wu,W.T.K.Cheng,C.M.Chen,S.P.Lin,C.H.Yen,andP.C.Yang2007-2026.MethodforexpressinghumanclottingfactorIXandlactoferrinproteinsinthelactatingmilkoftransgenicnon-humanmammals.TaiwanPatent,No.I273. 7.W.T.K.Cheng,C.M.Chen,S.H.Lin,C.H.Wang,C.J.Lin,andS.C.Wu2007-2025.MethodfortransgenicanimalsproducingbiologicallyactivehumanfactorVIIIintheirmilkdrivenbymammary-specificexpressioncassettewithintactorB-domain-deletedgeneconstructs.TaiwanPaten,No.I287578. 8.H.L.Chen,C.M.Chen2007NovelAntihypertensivePeptideAndUseThereof.TaiwanPatent,,No.096135346. 9.F.C.Liu,C.M.Chen2007IsolationofPorcineColipaseAndUseThereof.TaiwanPatent,No.11/901,989. 10.S.C.Wu,W.T.K.Cheng,C.M.Chen,S.P.Lin,C.H.Yen,andP.C.Yang2006-2025.Methodforexpressionmultiplerecombinantproteinsinthemilkoftransgenicnon-humanmammals.USAPatent,No.7,087,808. 11.C.M.Chen*,H.L.Chen,andW.T.K.Cheng2006-2025TransgenicAnimalsProducingLow-LactoseMilkandNewlyIdentifiedHumanSmallIntestinalExtracellularLactase-phlorizinHydrolase(ecLPH)Gene.USAPatent,No.7,501,554B. 12.C.M.Chen*,H.L.Chen,andW.T.K.Cheng2006TransgenicAnimalsProducingLow-LactoseMilkandNewlyIdentifiedHumanSmallIntestinalExtracellularLactase-phlorizinHydrolase(ecLPH)Gene.TaiwanPatent,No.095117017. 13.C.M.Chen,P.S.Yan,andT.H.M.Huang2002Methylationtargetarray(MTA)forhigh-throughputanalysisofpromoterhypermethylationinmultipletissuegenomes.USA,Canada,Europe,Japan,AustraliaPatents,(pending. 14.C.M.ChenW.T.K.Cheng,C.H.Hsu2002Allergen-containingtransgenicmilkforallergytreatment.EuropeanPatent,Applicationnumber:02252702.2;pendin. 15.C.M.Chen*,C.C.Chang,T.L.Weng,andW.T.K.Cheng2001-2019.Procedureforgenderdeterminationofgoatembryosbysex-specificsequencesofgoatamelogeningene.TaiwanPatent,No.140,077. 16.C.H.Hsu,W.T.K.Cheng,C.M.Chen2001Allergen-containingtransgenicmilkforallergytreatment.USAPatent,09/877,160. 17.C.H.Hsu,W.T.K.Cheng,C.M.Chen2001Allergen-containingtransgenicmilkforallergytreatment.USAPatent,09/877,16. 18.C.M.Chen*,andM.F.Kuo2000TheProcessforgrowthimprovementoffowlsusingrecombinantrGH-enrichedyeastcultureasfeedstuffadditive.USAPatent,No.09/563,742. 19.W.T.K.Cheng,C.M.Chen,C.L.Hu,C.H.Wang,andK.B.Choo1999-2017.Processforsexingcowembryos.USAPatent,No.5,876,942. 20.W.T.K.Cheng,C.M.Chen,C.L.Hu,C.H.Wang,andK.B.Choo1999-2017Sex-specificsequencesidentifiedfromamelogeningeneintheHolsteindairycattleandmethoddevelTaiwanPatent,No.101,194. G.學術活動  1.陳全木等2020主辦台灣發育生物學國際研討會(2020InternationalConferenceofTaiwanDevelopmentalBiologySociety).舉辦日期:2020/08/07-08. 2.陳全木等2020協辦國際生物催化暨農業生物科技學會國際研討會.舉辦日期:2020/10/23-24. 3.陳全木等2020主辦全國生科論文三分鐘口說競賽.舉辦日期:2020/11/07(中區初賽)、2020/11/28(全國總決賽). 4.陳全木等2010年澳洲Lorne基因體國際研討會. 5.陳全木等2010頂尖大學研發長訪英暨『台-英高等教育論壇. 6.陳全木等2009/09頂尖大學研發長訪歐盟-比利時、德國、法國. 7.陳全木等2009第100屆AACR美國癌症年.