一种治疗慢性肠炎的中药及其制备方法 - Google

2025-01-10

文章推薦指數： 80 %

投票人數：10人

一种治疗慢性肠炎的中药及其制备方法，是由广藿香、紫苏叶、白术、大腹皮、甘葛、苍术、白蒺藜、豆蔻、枳实、香附、川芎、橘皮、虎杖、元胡、薏苡仁、黄芩、大血藤、 ... WO2015149389A1-一种治疗慢性肠炎的中药及其制备方法 -GooglePatents 一种治疗慢性肠炎的中药及其制备方法 DownloadPDF Info Publicationnumber WO2015149389A1 WO2015149389A1 PCT/CN2014/075336 CN2014075336W WO2015149389A1 WO2015149389A1 WO2015149389A1 WO2015149389A1 CN2014075336W CN2014075336W CN2014075336W WO2015149389A1 WO2015149389A1 WO2015149389A1 Authority WO WIPO(PCT) Priorartkeywords atractylodes whitepeony chinesemedicine traditionalchinese patchouli Priorartdate 2014-03-31 Applicationnumber PCT/CN2014/075336 Otherlanguages English(en) French(fr) Inventor 袁志贤 OriginalAssignee 袁志贤 Prioritydate(Theprioritydateisanassumptionandisnotalegalconclusion.Googlehasnotperformedalegalanalysisandmakesnorepresentationastotheaccuracyofthedatelisted.) 2014-03-31 Filingdate 2014-04-15 Publicationdate 2015-10-08 2014-03-31 PrioritytoCN201410124715.8A priority Critical patent/CN103861015A/zh 2014-03-31 PrioritytoCN201410124715.8 priority 2014-04-15 Applicationfiledby袁志贤 filed Critical 袁志贤 2015-10-08 PublicationofWO2015149389A1 publication Critical patent/WO2015149389A1/zh Links Espacenet GlobalDossier PatentScope Discuss 239000003814 drug Substances 0.000 title claims abstract description 31 238000002360 preparationmethod Methods 0.000 title claims abstract description 27 208000004232 Enteritis Diseases 0.000 title claims abstract description 21 230000001684 chronic Effects 0.000 title claims abstract description 16 240000002505 Pogostemoncablin Species 0.000 claims abstract description 23 235000011751 Pogostemoncablin Nutrition 0.000 claims abstract description 23 240000001341 Reynoutriajaponica Species 0.000 claims abstract description 21 235000018167 Reynoutriajaponica Nutrition 0.000 claims abstract description 21 239000000203 mixture Substances 0.000 claims abstract description 15 235000004348 Perillafrutescens Nutrition 0.000 claims abstract description 12 240000009301 Coixlacryma-jobi Species 0.000 claims abstract description 11 240000003877 Perillafrutescens Species 0.000 claims abstract description 9 238000002156 mixing Methods 0.000 claims abstract description 5 241000132012 Atractylodes Species 0.000 claims description 50 235000008598 Paeonialactiflora Nutrition 0.000 claims description 35 240000004600 Paeonialactiflora Species 0.000 claims description 35 210000001015 Abdomen Anatomy 0.000 claims description 21 210000004369 Blood Anatomy 0.000 claims description 21 239000008280 blood Substances 0.000 claims description 21 LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemicalcompound data:image/svg+xml;base64,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 data:image/svg+xml;base64,PD94bWwgdmVyc2lvbj0nMS4wJyBlbmNvZGluZz0naXNvLTg4NTktMSc/Pgo8c3ZnIHZlcnNpb249JzEuMScgYmFzZVByb2ZpbGU9J2Z1bGwnCiAgICAgICAgICAgICAgeG1sbnM9J2h0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnJwogICAgICAgICAgICAgICAgICAgICAgeG1sbnM6cmRraXQ9J2h0dHA6Ly93d3cucmRraXQub3JnL3htbCcKICAgICAgICAgICAgICAgICAgICAgIHhtbG5zOnhsaW5rPSdodHRwOi8vd3d3LnczLm9yZy8xOTk5L3hsaW5rJwogICAgICAgICAgICAgICAgICB4bWw6c3BhY2U9J3ByZXNlcnZlJwp3aWR0aD0nODVweCcgaGVpZ2h0PSc4NXB4JyB2aWV3Qm94PScwIDAgODUgODUnPgo8IS0tIEVORCBPRiBIRUFERVIgLS0+CjxyZWN0IHN0eWxlPSdvcGFjaXR5OjEuMDtmaWxsOiNGRkZGRkY7c3Ryb2tlOm5vbmUnIHdpZHRoPSc4NS4wJyBoZWlnaHQ9Jzg1LjAnIHg9JzAuMCcgeT0nMC4wJz4gPC9yZWN0Pgo8cGF0aCBjbGFzcz0nYm9uZC0wIGF0b20tMCBhdG9tLTEnIGQ9J00gMy40LDQ3LjUgTCAzNS4xLDI5LjInIHN0eWxlPSdmaWxsOm5vbmU7ZmlsbC1ydWxlOmV2ZW5vZGQ7c3Ryb2tlOiMzQjQxNDM7c3Ryb2tlLXdpZHRoOjEuMHB4O3N0cm9rZS1saW5lY2FwOmJ1dHQ7c3Ryb2tlLWxpbmVqb2luOm1pdGVyO3N0cm9rZS1vcGFjaXR5OjEnIC8+CjxwYXRoIGNsYXNzPSdib25kLTEgYXRvbS0xIGF0b20tMicgZD0nTSAzNS4xLDI5LjIgTCA0OC4zLDM2LjgnIHN0eWxlPSdmaWxsOm5vbmU7ZmlsbC1ydWxlOmV2ZW5vZGQ7c3Ryb2tlOiMzQjQxNDM7c3Ryb2tlLXdpZHRoOjEuMHB4O3N0cm9rZS1saW5lY2FwOmJ1dHQ7c3Ryb2tlLWxpbmVqb2luOm1pdGVyO3N0cm9rZS1vcGFjaXR5OjEnIC8+CjxwYXRoIGNsYXNzPSdib25kLTEgYXRvbS0xIGF0b20tMicgZD0nTSA0OC4zLDM2LjggTCA2MS41LDQ0LjQnIHN0eWxlPSdmaWxsOm5vbmU7ZmlsbC1ydWxlOmV2ZW5vZGQ7c3Ryb2tlOiNFODQyMzU7c3Ryb2tlLXdpZHRoOjEuMHB4O3N0cm9rZS1saW5lY2FwOmJ1dHQ7c3Ryb2tlLWxpbmVqb2luOm1pdGVyO3N0cm9rZS1vcGFjaXR5OjEnIC8+Cjx0ZXh0IHg9JzYyLjQnIHk9JzU0LjgnIGNsYXNzPSdhdG9tLTInIHN0eWxlPSdmb250LXNpemU6MTRweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID5PPC90ZXh0Pgo8dGV4dCB4PSc3Mi41JyB5PSc1NC44JyBjbGFzcz0nYXRvbS0yJyBzdHlsZT0nZm9udC1zaXplOjE0cHg7Zm9udC1zdHlsZTpub3JtYWw7Zm9udC13ZWlnaHQ6bm9ybWFsO2ZpbGwtb3BhY2l0eToxO3N0cm9rZTpub25lO2ZvbnQtZmFtaWx5OnNhbnMtc2VyaWY7dGV4dC1hbmNob3I6c3RhcnQ7ZmlsbDojRTg0MjM1JyA+SDwvdGV4dD4KPC9zdmc+Cg== CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 19 210000003491 Skin Anatomy 0.000 claims description 18 239000000843 powder Substances 0.000 claims description 18 240000006394 Sorghumbicolor Species 0.000 claims description 17 235000019713 millet Nutrition 0.000 claims description 17 XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances data:image/svg+xml;base64,PD94bWwgdmVyc2lvbj0nMS4wJyBlbmNvZGluZz0naXNvLTg4NTktMSc/Pgo8c3ZnIHZlcnNpb249JzEuMScgYmFzZVByb2ZpbGU9J2Z1bGwnCiAgICAgICAgICAgICAgeG1sbnM9J2h0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnJwogICAgICAgICAgICAgICAgICAgICAgeG1sbnM6cmRraXQ9J2h0dHA6Ly93d3cucmRraXQub3JnL3htbCcKICAgICAgICAgICAgICAgICAgICAgIHhtbG5zOnhsaW5rPSdodHRwOi8vd3d3LnczLm9yZy8xOTk5L3hsaW5rJwogICAgICAgICAgICAgICAgICB4bWw6c3BhY2U9J3ByZXNlcnZlJwp3aWR0aD0nMzAwcHgnIGhlaWdodD0nMzAwcHgnIHZpZXdCb3g9JzAgMCAzMDAgMzAwJz4KPCEtLSBFTkQgT0YgSEVBREVSIC0tPgo8cmVjdCBzdHlsZT0nb3BhY2l0eToxLjA7ZmlsbDojRkZGRkZGO3N0cm9rZTpub25lJyB3aWR0aD0nMzAwLjAnIGhlaWdodD0nMzAwLjAnIHg9JzAuMCcgeT0nMC4wJz4gPC9yZWN0Pgo8dGV4dCB4PScxMDAuNScgeT0nMTcwLjAnIGNsYXNzPSdhdG9tLTAnIHN0eWxlPSdmb250LXNpemU6NDBweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID5IPC90ZXh0Pgo8dGV4dCB4PScxMjYuMScgeT0nMTg2LjAnIGNsYXNzPSdhdG9tLTAnIHN0eWxlPSdmb250LXNpemU6MjZweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID4yPC90ZXh0Pgo8dGV4dCB4PScxMzguMCcgeT0nMTcwLjAnIGNsYXNzPSdhdG9tLTAnIHN0eWxlPSdmb250LXNpemU6NDBweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID5PPC90ZXh0Pgo8L3N2Zz4K data:image/svg+xml;base64,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 O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13 240000002943 Elettariacardamomum Species 0.000 claims description 12 235000006533 astragalus Nutrition 0.000 claims description 12 235000005300 cardamomo Nutrition 0.000 claims description 12 235000004347 Perilla Nutrition 0.000 claims description 11 239000000706 filtrate Substances 0.000 claims description 11 241001061264 Astragalus Species 0.000 claims description 10 210000000456 talusbone Anatomy 0.000 claims description 10 235000017784 Mespilusgermanica Nutrition 0.000 claims description 8 235000000560 Mimusopselengi Nutrition 0.000 claims description 8 235000007837 Vangueriainfausta Nutrition 0.000 claims description 8 239000000284 extract Substances 0.000 claims description 7 239000000571 coke Substances 0.000 claims description 6 238000010992 reflux Methods 0.000 claims description 6 238000001914 filtration Methods 0.000 claims description 5 238000010438 heattreatment Methods 0.000 claims description 5 235000013527 beancurd Nutrition 0.000 claims description 4 230000002829 reduced Effects 0.000 claims description 4 235000008247 Echinochloafrumentacea Nutrition 0.000 claims description 3 240000002533 Echinochloafrumentacea Species 0.000 claims description 3 240000007594 Oryzasativa Species 0.000 claims description 3 235000007164 Oryzasativa Nutrition 0.000 claims description 3 235000009566 rice Nutrition 0.000 claims description 3 239000002904 solvent Substances 0.000 claims description 3 238000009835 boiling Methods 0.000 claims description 2 241001573366 Astragalusmembranaceus Species 0.000 claims 2 240000002645 Mimusopselengi Species 0.000 claims 1 235000019764 SoybeanMeal Nutrition 0.000 claims 1 244000138993 panchioli Species 0.000 claims 1 -1 simmerfor1hour Substances 0.000 claims 1 239000004455 soybeanmeal Substances 0.000 claims 1 241000092665 Atractylodesmacrocephala Species 0.000 abstract description 3 238000000034 method Methods 0.000 abstract description 3 241000132011 Atractylodeslancea Species 0.000 abstract description 2 235000007226 Setariaitalica Nutrition 0.000 abstract description 2 240000005498 Setariaitalica Species 0.000 abstract description 2 239000007788 liquid Substances 0.000 abstract description 2 241000010428 Alpiniakatsumadae Species 0.000 abstract 1 240000005368 Arecacatechu Species 0.000 abstract 1 235000006226 Arecacatechu Nutrition 0.000 abstract 1 241001313857 Bletillastriata Species 0.000 abstract 1 235000007354 Coixlacrymajobi Nutrition 0.000 abstract 1 241000830532 Corydalisyanhusuo Species 0.000 abstract 1 240000000628 Cyperusrotundus Species 0.000 abstract 1 235000016854 Cyperusrotundus Nutrition 0.000 abstract 1 241000112528 Ligusticumstriatum Species 0.000 abstract 1 241000539605 Puerariaedulis Species 0.000 abstract 1 241000501113 Sargentodoxacuneata Species 0.000 abstract 1 240000004534 Scutellariabaicalensis Species 0.000 abstract 1 235000017089 Scutellariabaicalensis Nutrition 0.000 abstract 1 241001533104 Tribulusterrestris Species 0.000 abstract 1 238000002481 ethanolextraction Methods 0.000 abstract 1 238000000227 grinding Methods 0.000 abstract 1 239000004615 ingredient Substances 0.000 abstract 1 210000000952 Spleen Anatomy 0.000 description 33 230000000694 effects Effects 0.000 description 33 210000002784 Stomach Anatomy 0.000 description 28 206010012735 Diarrhoea Diseases 0.000 description 24 201000008286 diarrhea Diseases 0.000 description 24 206010047700 Vomiting Diseases 0.000 description 19 208000002193 Pain Diseases 0.000 description 16 230000036407 pain Effects 0.000 description 16 230000000968 intestinal Effects 0.000 description 14 206010062717 Increasedupperairwaysecretion Diseases 0.000 description 12 210000004185 Liver Anatomy 0.000 description 12 206010036790 Productivecough Diseases 0.000 description 12 210000003802 Sputum Anatomy 0.000 description 12 206010042674 Swelling Diseases 0.000 description 12 238000002052 colonoscopy Methods 0.000 description 12 230000002522 swelling Effects 0.000 description 12 208000004998 AbdominalPain Diseases 0.000 description 10 206010000060 Abdominaldistension Diseases 0.000 description 9 210000000936 Intestines Anatomy 0.000 description 9 241000283973 Oryctolaguscuniculus Species 0.000 description 8 240000002624 Mespilusgermanica Species 0.000 description 7 238000001784 detoxification Methods 0.000 description 7 239000000835 fiber Substances 0.000 description 7 239000002994 rawmaterial Substances 0.000 description 7 206010019233 Headache Diseases 0.000 description 6 210000004072 Lung Anatomy 0.000 description 6 230000017531 bloodcirculation Effects 0.000 description 6 235000005911 diet Nutrition 0.000 description 6 230000037213 diet Effects 0.000 description 6 230000002401 inhibitoryeffect Effects 0.000 description 6 230000003902 lesions Effects 0.000 description 6 206010008469 Chestdiscomfort Diseases 0.000 description 5 208000008313 Contusions Diseases 0.000 description 5 208000005171 Dysmenorrhea Diseases 0.000 description 5 206010013935 Dysmenorrhoea Diseases 0.000 description 5 210000001035 GastrointestinalTract Anatomy 0.000 description 5 210000002216 Heart Anatomy 0.000 description 5 235000009508 confectionery Nutrition 0.000 description 5 230000001605 fetal Effects 0.000 description 5 230000002496 gastric Effects 0.000 description 5 231100000869 headache Toxicity 0.000 description 5 210000002429 largeintestine Anatomy 0.000 description 5 239000002398 materiamedica Substances 0.000 description 5 231100000252 nontoxic Toxicity 0.000 description 5 230000002269 spontaneous Effects 0.000 description 5 238000005429 turbidity Methods 0.000 description 5 206010011224 Cough Diseases 0.000 description 4 206010018836 Haematochezia Diseases 0.000 description 4 208000002287 Hemorrhoids Diseases 0.000 description 4 206010027339 Menstruationirregular Diseases 0.000 description 4 201000010099 disease Diseases 0.000 description 4 229940079593 drugs Drugs 0.000 description 4 201000006549 dyspepsia Diseases 0.000 description 4 230000003000 nontoxic Effects 0.000 description 4 210000000813 smallintestine Anatomy 0.000 description 4 201000004647 tineapedis Diseases 0.000 description 4 206010001928 Amenorrhoea Diseases 0.000 description 3 206010023126 Jaundice Diseases 0.000 description 3 210000003097 Mucus Anatomy 0.000 description 3 206010030113 Oedema Diseases 0.000 description 3 241000229722 Perilla Species 0.000 description 3 235000010627 Phaseolusvulgaris Nutrition 0.000 description 3 240000005158 Phaseolusvulgaris Species 0.000 description 3 241001522129 Pinellia Species 0.000 description 3 210000004915 Pus Anatomy 0.000 description 3 206010037660 Pyrexia Diseases 0.000 description 3 206010072736 Rheumaticdisease Diseases 0.000 description 3 206010068760 Ulcers Diseases 0.000 description 3 201000000736 amenorrhea Diseases 0.000 description 3 231100000540 amenorrhea Toxicity 0.000 description 3 230000000767 anti-ulcer Effects 0.000 description 3 235000019789 appetite Nutrition 0.000 description 3 230000036528 appetite Effects 0.000 description 3 210000000038 chest Anatomy 0.000 description 3 238000003745 diagnosis Methods 0.000 description 3 235000012054 meals Nutrition 0.000 description 3 210000000056 organs Anatomy 0.000 description 3 239000000047 product Substances 0.000 description 3 230000000306 recurrent Effects 0.000 description 3 231100000397 ulcer Toxicity 0.000 description 3 206010000087 Abdominalpainupper Diseases 0.000 description 2 229960004373 Acetylcholine Drugs 0.000 description 2 241000675108 Citrustangerina Species 0.000 description 2 206010010774 Constipation Diseases 0.000 description 2 208000002173 Dizziness Diseases 0.000 description 2 206010059866 Drugresistance Diseases 0.000 description 2 208000000718 DuodenalUlcer Diseases 0.000 description 2 208000001848 Dysentery Diseases 0.000 description 2 206010013954 Dysphoria Diseases 0.000 description 2 206010013990 Dysuria Diseases 0.000 description 2 210000002683 Foot Anatomy 0.000 description 2 210000000232 Gallbladder Anatomy 0.000 description 2 240000004670 Glycyrrhizaechinata Species 0.000 description 2 235000001453 Glycyrrhizaechinata Nutrition 0.000 description 2 235000006200 Glycyrrhizaglabra Nutrition 0.000 description 2 235000017382 Glycyrrhizalepidota Nutrition 0.000 description 2 241000238631 Hexapoda Species 0.000 description 2 206010020772 Hypertension Diseases 0.000 description 2 210000003734 Kidney Anatomy 0.000 description 2 229940010454 Licorice Drugs 0.000 description 2 241000218378 Magnolia Species 0.000 description 2 206010028813 Nausea Diseases 0.000 description 2 229940100688 OralSolution Drugs 0.000 description 2 241000736199 Paeonia Species 0.000 description 2 235000006484 Paeoniaofficinalis Nutrition 0.000 description 2 241000207929 Scutellaria Species 0.000 description 2 241000913745 Spatholobus Species 0.000 description 2 206010042220 Stressulcer Diseases 0.000 description 2 OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemicalcompound data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 2 239000002253 acid Substances 0.000 description 2 238000004378 airconditioning Methods 0.000 description 2 230000003042 antagnostic Effects 0.000 description 2 230000001166 anti-perspirant Effects 0.000 description 2 239000003213 antiperspirant Substances 0.000 description 2 230000003247 decreasing Effects 0.000 description 2 238000007791 dehumidification Methods 0.000 description 2 230000029087 digestion Effects 0.000 description 2 230000001079 digestive Effects 0.000 description 2 238000001035 drying Methods 0.000 description 2 230000004634 feedingbehavior Effects 0.000 description 2 235000013305 food Nutrition 0.000 description 2 NTYJJOPFIAHURM-UHFFFAOYSA-N histamine Chemicalcompound data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 2 230000002147 killing Effects 0.000 description 2 235000014063 licoriceroot Nutrition 0.000 description 2 201000004792 malaria Diseases 0.000 description 2 210000004914 menses Anatomy 0.000 description 2 230000002175 menstrual Effects 0.000 description 2 230000005906 menstruation Effects 0.000 description 2 231100000957 nosideeffect Toxicity 0.000 description 2 230000036961 partial Effects 0.000 description 2 230000008506 pathogenesis Effects 0.000 description 2 230000035935 pregnancy Effects 0.000 description 2 230000001737 promoting Effects 0.000 description 2 230000001105 regulatory Effects 0.000 description 2 230000001568 sexual Effects 0.000 description 2 231100000486 sideeffect Toxicity 0.000 description 2 230000035922 thirst Effects 0.000 description 2 239000000341 volatileoil Substances 0.000 description 2 241000251468 Actinopterygii Species 0.000 description 1 240000002333 Amomumvillosum Species 0.000 description 1 206010002153 Analfissure Diseases 0.000 description 1 206010003011 Appendicitis Diseases 0.000 description 1 208000006820 Arthralgia Diseases 0.000 description 1 206010003497 Asphyxia Diseases 0.000 description 1 208000006673 Asthma Diseases 0.000 description 1 241000984231 Atractylodeschinensis Species 0.000 description 1 206010063659 Aversion Diseases 0.000 description 1 241000894006 Bacteria Species 0.000 description 1 210000000941 Bile Anatomy 0.000 description 1 210000000601 BloodCells Anatomy 0.000 description 1 206010006298 Breastpain Diseases 0.000 description 1 206010006312 Breastswelling Diseases 0.000 description 1 206010006451 Bronchitis Diseases 0.000 description 1 240000001548 Camelliajaponica Species 0.000 description 1 240000000218 Cannabissativa Species 0.000 description 1 206010007247 Carbuncle Diseases 0.000 description 1 210000003169 CentralNervousSystem Anatomy 0.000 description 1 206010008479 Chestpain Diseases 0.000 description 1 206010008631 Cholera Diseases 0.000 description 1 206010009269 Cleftpalate Diseases 0.000 description 1 241000007126 Codonopsispilosula Species 0.000 description 1 206010009887 Colitis Diseases 0.000 description 1 244000247747 Coptisgroenlandica Species 0.000 description 1 235000002991 Coptisgroenlandica Nutrition 0.000 description 1 208000004981 CoronaryDisease Diseases 0.000 description 1 210000000805 Cytoplasm Anatomy 0.000 description 1 206010012601 Diabetesmellitus Diseases 0.000 description 1 241000668709 Dipterocarpuscostatus Species 0.000 description 1 208000010515 Dystocia Diseases 0.000 description 1 208000005189 Embolism Diseases 0.000 description 1 241000196324 Embryophyta Species 0.000 description 1 208000010201 Exanthema Diseases 0.000 description 1 210000003414 Extremities Anatomy 0.000 description 1 206010015995 Eyelidptosis Diseases 0.000 description 1 210000003754 Fetus Anatomy 0.000 description 1 208000009531 FissureinAno Diseases 0.000 description 1 208000002513 FlankPain Diseases 0.000 description 1 241000233866 Fungi Species 0.000 description 1 210000004211 GastricAcid Anatomy 0.000 description 1 210000004051 GastricJuice Anatomy 0.000 description 1 208000005577 Gastroenteritis Diseases 0.000 description 1 206010019133 Hangover Diseases 0.000 description 1 208000000616 Hemoptysis Diseases 0.000 description 1 206010019909 Hernia Diseases 0.000 description 1 206010049077 Herniapain Diseases 0.000 description 1 206010020039 Hiccups Diseases 0.000 description 1 210000001624 Hip Anatomy 0.000 description 1 241000282313 Hyaenidae Species 0.000 description 1 208000008454 Hyperhidrosis Diseases 0.000 description 1 210000003405 Ileum Anatomy 0.000 description 1 208000008081 IntestinalFistula Diseases 0.000 description 1 210000003127 Knee Anatomy 0.000 description 1 241000207923 Lamiaceae Species 0.000 description 1 206010024971 Lowerrespiratorytractinfection Diseases 0.000 description 1 208000006662 Mastodynia Diseases 0.000 description 1 210000000214 Mouth Anatomy 0.000 description 1 241000699670 Mussp. Species 0.000 description 1 235000003805 MusaABBGroup Nutrition 0.000 description 1 210000002464 Muscle,Smooth,Vascular Anatomy 0.000 description 1 210000001331 Nose Anatomy 0.000 description 1 240000003982 Ocimumbasilicum Species 0.000 description 1 235000010676 Ocimumbasilicum Nutrition 0.000 description 1 241000237502 Ostreidae Species 0.000 description 1 240000004678 Panaxpseudoginseng Species 0.000 description 1 235000003140 Panaxquinquefolius Nutrition 0.000 description 1 240000001090 Papaversomniferum Species 0.000 description 1 240000004331 Plantagomajor Species 0.000 description 1 235000015266 Plantagomajor Nutrition 0.000 description 1 206010035664 Pneumonia Diseases 0.000 description 1 241000209504 Poaceae Species 0.000 description 1 231100000614 Poison Toxicity 0.000 description 1 241001619461 Poria Species 0.000 description 1 208000003251 Pruritus Diseases 0.000 description 1 235000014360 Punicagranatum Nutrition 0.000 description 1 240000006764 Punicagranatum Species 0.000 description 1 210000001187 Pylorus Anatomy 0.000 description 1 206010037844 Rash Diseases 0.000 description 1 206010052251 Respiratorytractcongestion Diseases 0.000 description 1 241000282898 Susscrofa Species 0.000 description 1 210000004243 Sweat Anatomy 0.000 description 1 241001122767 Theaceae Species 0.000 description 1 206010053476 Traumatichaemorrhage Diseases 0.000 description 1 206010046306 Upperrespiratorytractinfection Diseases 0.000 description 1 206010046788 Uterinehaemorrhage Diseases 0.000 description 1 206010046814 Uterineprolapse Diseases 0.000 description 1 241000700605 Viruses Species 0.000 description 1 235000006886 Zingiberofficinale Nutrition 0.000 description 1 240000007329 Zingiberofficinale Species 0.000 description 1 238000009825 accumulation Methods 0.000 description 1 230000003213 activating Effects 0.000 description 1 UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemicalcompound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 13.6,114.8 L 22.8,123.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 22.8,123.2 L 31.9,131.6' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 57.8,138.3 L 70.5,134.3' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 70.5,134.3 L 83.3,130.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 83.3,130.3 L 113.6,158.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 113.6,158.2 L 110.7,171.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 110.7,171.3 L 107.7,184.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 113.6,158.2 L 152.9,145.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 152.9,145.9 L 161.8,105.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 162.3,141.6 L 168.5,113.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-5' d='M 183.2,173.7 L 152.9,145.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 161.8,105.7 L 201.1,93.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 201.1,93.4 L 231.5,121.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 200.1,103.6 L 221.3,123.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 231.5,121.2 L 244.2,117.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 244.2,117.2 L 256.9,113.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 231.5,121.2 L 222.5,161.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 222.5,161.4 L 231.6,169.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 231.6,169.8 L 240.8,178.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 222.5,161.4 L 183.2,173.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 214.1,155.4 L 186.6,164.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='39.0' y='150.9' class='atom-1' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='39.0' y='165.4' class='atom-1' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >H</text>
<text x='99.7' y='206.6' class='atom-4' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='111.0' y='206.6' class='atom-4' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='265.8' y='117.1' class='atom-9' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='277.2' y='117.1' class='atom-9' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='247.9' y='197.5' class='atom-11' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='259.3' y='197.5' class='atom-11' style='font-size:16px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 3.4,31.9 L 6.6,34.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 6.6,34.9 L 9.8,37.8' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 14.0,39.1 L 18.4,37.7' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 18.4,37.7 L 22.9,36.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 22.9,36.3 L 31.4,44.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 31.4,44.1 L 30.4,48.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 30.4,48.7 L 29.4,53.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 31.4,44.1 L 42.4,40.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 42.4,40.6 L 44.9,29.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 45.1,39.5 L 46.8,31.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-5' d='M 50.9,48.5 L 42.4,40.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 44.9,29.4 L 56.0,25.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 56.0,25.9 L 64.5,33.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 55.7,28.8 L 61.6,34.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 64.5,33.7 L 68.9,32.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 68.9,32.3 L 73.4,30.9' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 64.5,33.7 L 62.0,45.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 62.0,45.0 L 65.2,47.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 65.2,47.9 L 68.4,50.9' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 62.0,45.0 L 50.9,48.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-10 atom-12' d='M 59.6,43.3 L 51.9,45.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='10.1' y='42.7' class='atom-1' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='10.1' y='48.0' class='atom-1' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >H</text>
<text x='27.1' y='58.4' class='atom-4' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='31.2' y='58.4' class='atom-4' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='73.7' y='33.3' class='atom-9' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='77.8' y='33.3' class='atom-9' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='68.7' y='55.8' class='atom-11' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='72.8' y='55.8' class='atom-11' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
</svg>
 CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 1 210000003484 anatomy Anatomy 0.000 description 1 230000000954 anitussive Effects 0.000 description 1 230000001760 anti-analgesic Effects 0.000 description 1 230000003110 anti-inflammatory Effects 0.000 description 1 210000000436 anus Anatomy 0.000 description 1 201000010188 anusdisease Diseases 0.000 description 1 230000001363 autoimmune Effects 0.000 description 1 230000036760 bodytemperature Effects 0.000 description 1 201000011510 cancer Diseases 0.000 description 1 235000013339 cereals Nutrition 0.000 description 1 235000018597 commoncamellia Nutrition 0.000 description 1 230000003750 conditioning Effects 0.000 description 1 230000037028 contractionfrequency Effects 0.000 description 1 238000007796 conventionalmethod Methods 0.000 description 1 201000008739 coronaryarterydisease Diseases 0.000 description 1 230000013872 defecation Effects 0.000 description 1 230000035622 drinking Effects 0.000 description 1 235000021271 drinking Nutrition 0.000 description 1 235000013399 ediblefruits Nutrition 0.000 description 1 239000002158 endotoxin Substances 0.000 description 1 238000005516 engineeringprocess Methods 0.000 description 1 230000002708 enhancing Effects 0.000 description 1 230000029578 entryintohost Effects 0.000 description 1 201000005884 exanthem Diseases 0.000 description 1 230000002964 excitative Effects 0.000 description 1 230000002550 fecal Effects 0.000 description 1 238000009472 formulation Methods 0.000 description 1 235000019525 fullness Nutrition 0.000 description 1 238000002309 gasification Methods 0.000 description 1 230000027119 gastricacidsecretion Effects 0.000 description 1 230000005176 gastrointestinalmotility Effects 0.000 description 1 238000003304 gavage Methods 0.000 description 1 235000008397 ginger Nutrition 0.000 description 1 235000008434 ginseng Nutrition 0.000 description 1 235000005035 ginseng Nutrition 0.000 description 1 230000023597 hemostasis Effects 0.000 description 1 229960001340 histamine Drugs 0.000 description 1 239000010015 huanglian Substances 0.000 description 1 235000003642 hunger Nutrition 0.000 description 1 238000007654 immersion Methods 0.000 description 1 230000036039 immunity Effects 0.000 description 1 230000002475 laxative Effects 0.000 description 1 239000008141 laxative Substances 0.000 description 1 238000002386 leaching Methods 0.000 description 1 201000005505 measles Diseases 0.000 description 1 230000027939 micturition Effects 0.000 description 1 230000037257 musclegrowth Effects 0.000 description 1 231100000862 numbness Toxicity 0.000 description 1 230000000414 obstructive Effects 0.000 description 1 239000003921 oil Substances 0.000 description 1 230000001151 othereffect Effects 0.000 description 1 235000020636 oyster Nutrition 0.000 description 1 244000045947 parasites Species 0.000 description 1 230000008855 peristalsis Effects 0.000 description 1 230000035479 physiologicaleffects,processesandfunctions Effects 0.000 description 1 239000002574 poison Substances 0.000 description 1 230000000607 poisoning Effects 0.000 description 1 231100000572 poisoning Toxicity 0.000 description 1 230000001141 propulsive Effects 0.000 description 1 201000003004 ptosis Diseases 0.000 description 1 230000002685 pulmonary Effects 0.000 description 1 238000010791 quenching Methods 0.000 description 1 230000000171 quenching Effects 0.000 description 1 230000000552 rheumatic Effects 0.000 description 1 150000003839 salts Chemicalclass 0.000 description 1 230000028327 secretion Effects 0.000 description 1 239000003998 snakevenom Substances 0.000 description 1 239000011780 sodiumchloride Substances 0.000 description 1 239000007787 solid Substances 0.000 description 1 230000001629 suppression Effects 0.000 description 1 230000035900 sweating Effects 0.000 description 1 230000001225 therapeutic Effects 0.000 description 1 239000000052 vinegar Substances 0.000 description 1 235000019156 vitaminB Nutrition 0.000 description 1 239000011720 vitaminB Substances 0.000 description 1 Classifications A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/88—Liliopsida(monocotyledons) A61K36/899—PoaceaeorGramineae(Grassfamily),e.g.bamboo,cornorsugarcane A61K36/8994—Coix(Job'stears) A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/23—ApiaceaeorUmbelliferae(Carrotfamily),e.g.dill,chervil,corianderorcumin A61K36/236—Ligusticum(licorice-root) A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/28—AsteraceaeorCompositae(AsterorSunflowerfamily),e.g.chamomile,feverfew,yarroworechinacea A61K36/284—Atractylodes A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/48—FabaceaeorLeguminosae(PeaorLegumefamily);Caesalpiniaceae;Mimosaceae;Papilionaceae A61K36/488—Pueraria(kudzu) A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/50—Fumariaceae(Fumitoryfamily),e.g.bleedingheart A61K36/505—Corydalis A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/53—LamiaceaeorLabiatae(Mintfamily),e.g.thyme,rosemaryorlavender A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/53—LamiaceaeorLabiatae(Mintfamily),e.g.thyme,rosemaryorlavender A61K36/535—Perilla(beefsteakplant) A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/53—LamiaceaeorLabiatae(Mintfamily),e.g.thyme,rosemaryorlavender A61K36/537—Salvia(sage) A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/70—Polygonaceae(Buckwheatfamily),e.g.spineflowerordock A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/185—Magnoliopsida(dicotyledons) A61K36/75—Rutaceae(Ruefamily) A61K36/754—Evodia A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/88—Liliopsida(monocotyledons) A61K36/889—Arecaceae,PalmaeorPalmaceae(Palmfamily),e.g.dateorcoconutpalmorpalmetto A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/88—Liliopsida(monocotyledons) A61K36/89—Cyperaceae(Sedgefamily) A61K36/8905—Cyperus(flatsedge) A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/88—Liliopsida(monocotyledons) A61K36/898—Orchidaceae(Orchidfamily) A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61K—PREPARATIONSFORMEDICAL,DENTAL,ORTOILETPURPOSES A61K36/00—Medicinalpreparationsofundeterminedconstitutioncontainingmaterialfromalgae,lichens,fungiorplants,orderivativesthereof,e.g.traditionalherbalmedicines A61K36/18—Magnoliophyta(angiosperms) A61K36/88—Liliopsida(monocotyledons) A61K36/906—Zingiberaceae(Gingerfamily) A61K36/9062—Alpinia,e.g.redgingerorgalangal A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61P—SPECIFICTHERAPEUTICACTIVITYOFCHEMICALCOMPOUNDSORMEDICINALPREPARATIONS A61P1/00—Drugsfordisordersofthealimentarytractorthedigestivesystem A—HUMANNECESSITIES A61—MEDICALORVETERINARYSCIENCE;HYGIENE A61P—SPECIFICTHERAPEUTICACTIVITYOFCHEMICALCOMPOUNDSORMEDICINALPREPARATIONS A61P1/00—Drugsfordisordersofthealimentarytractorthedigestivesystem A61P1/04—Drugsfordisordersofthealimentarytractorthedigestivesystemforulcers,gastritisorrefluxesophagitis,e.g.antacids,inhibitorsofacidsecretion,mucosalprotectants Abstract 一种治疗慢性肠炎的中药及其制备方法，是由广藿香、紫苏叶、白术、大腹皮、甘葛、苍术、白蒺藜、豆蔻、枳实、香附、川芎、橘皮、虎杖、元胡、薏苡仁、黄芩、大血藤、白芨和小米经过粉碎、煎煮、乙醇提取及混合等工序制备成的组合物液态制剂。

Description 一种治疔慢性肠炎的中药及其制备方法技术领域本发明涉及一种治疗肠炎的中药，具体涉及一种治疗慢性肠炎的中药及其制备方法。

背景技术肠指的是从胃幽门至肛门的消化管，肠是消化管中最长的一段，也是功能最重要的一段。

肠道是人体最大的消化器官，也是人体最大的排毒器官。

从生理学、解剖学、细胞学的角度来看，大肠排毒占人体排毒的85%以上；人体的80%免疫结构在肠道周围，内毒素的堆积是自体免疫力的杀手。

肠炎主要指胃肠炎、小肠炎和结肠炎，一般认为是由细菌、病毒、真菌和寄生虫等引起。

临床主要表现有恶心、呕吐、腹痛、腹泻、大便粘滞带血、大便不成形，部分病人可有发热及里急后重感觉。

近年来，随着人们生活水平的提高和生活方式的改变，慢性肠炎的发病率呈上升趋势，并且该病病程较长，难以根治，反复发作，严重影响着人们的身体健康和生活质量，且癌变率达5%左右。

尽管目前用于治疗肠炎的药物不算少，但西药治标不治本，用久了容易产生抗药性，副作用比较大，损害肝脏、肾脏及血细胞，而且药效不稳定，容易反复发作。

发明内容本发明的目的即在于针对上述不足，在祖传秘方的基础上，结合现代中西医技术，提供一种治疗慢性肠炎的中药，具体的说是提供这种中药及其制备方法，本发明肠炎治疗效果明显，而且无毒，无副作用，效果稳定，制取工艺简便易行。

本发明的技术方案如下所述：本发明制剂是由广藿香、紫苏叶、白术、大腹皮、甘葛、苍术、白蒺藜、豆蔻、枳实、香附、川芎、橘皮、虎杖、元胡、薏苡仁、黄芩、大血藤、白芨和小米制备成的组合物制剂，其中各组分的质量配比为：广藿香12-20g紫苏叶10-22g白术 8-18g 大腹皮10-18g甘葛8-15g苍术 10-20g 白蒺藜8-16g豆蔻12-20g枳实8-16g 香附10-18g川芎10-18g橘皮10-18g 虎杖8-15g元胡6-15g薏苡仁8-15g 黄芩10-18g大血藤8-16g白芨8—15g 小米10-20g。

为了获得更好的效果，本发明可优选的原料质量配比为: 广藿香12-18g紫紫苏苏叶叶1100--1188gg白术-12g 大腹皮12-L8g甘葛8-12g苍术0-15g 白蒺藜8-12g豆蔻12-16g枳实8-L2g香附10-15g川芎10-14g橘皮10-15g虎杖8-12g元胡6-K)g薏苡仁-12g 黄芩10-15g大血藤8-12g白芨8-1¾小米12-18g。

当然，为了获得进一步好的效果，本发明还可优选的原料质量配比为：广藿香15g紫苏叶12g白术9g大腹皮15g甘葛10g苍术12g白蒺藜12g豆蔻10g枳实8g香附12g川芎Hg橘皮12g虎杖8g元胡8g薏苡仁12g黄芩10g大血藤8g白芨10g小米15g。

上述治疗慢性肠炎中药的制备方法，包括如下步骤： 1)、将紫苏叶放入小锅进行小炒至表面微焦，然后经粉碎机粉碎并过80目筛，备用； 2)、将广藿香、白术、大腹皮、甘葛、白蒺藜、豆蔻、枳实、小米、黄芩、大血藤按比例配好，经过粉碎机粉碎成粉末并过90目筛，自然晾干，备用； 3)、将歩骤1)和2)中的各组分粉末混合在一起，加入纯净水煎煮两次，第一次加入10倍纯净水煎煮1小时，提取滤液备用；第二次加入6倍纯净水煎煮半小时，然后合并煎液并过滤，备用； 4)、将剩下的苍术、香附、川芎、橘皮、虎杖、元胡、薏苡仁、白芨按比例配好，经过粉碎机粉碎成粉末并过80目筛，自然晾干，备用； 5)、将歩骤4)中各组分粉末混合在一起，加入4〜6倍70%〜80%的乙醇，加热回流3〜5个小时，提取过滤获得滤液；然后在剩下的药渣中再次加入2〜4倍65%〜75%的乙醇，加热回流2〜3个小时，提取过滤获得滤液;将两次获得的滤液合并在一起，减压浓缩除去乙醇溶剂，干燥，获得干膏； 6)、将上述歩骤5)中获得的干膏进行超微粉碎成粉末并过200目筛，然后将粉末加入3)步骤中的合并煎液，混合摇匀即可制得。

制取的上述中药组合物溶液制剂可以用于口服，如果能够早中晚各适量饮用一次并长期饮用，效果更好。

本发明的理论依据在于: 广藿香，味辛，微温。

归脾、胃、肺经。

芳香化浊，开胃止呕，发表解暑。

用于湿浊中阻，脘痞呕吐，暑湿倦怠，胸闷不舒，寒湿闭暑，腹痛吐泻，鼻渊头痛。

用于湿阻中焦、脘闷纳呆之症候，在临床上常与虎杖等同用。

用于湿温出起，可配苍术、大腹皮、黄芩等同用。

用于感受秽浊、呕吐泄泻之症，可配紫苏叶、豆蔻、白蒺藜等同用。

对于胃寒呕吐之症，可配半夏同用；如湿热者，可配黄莲、竹茹；脾胃虚弱者，可配党参、甘草；妊娠呕吐，可配砂仁同用。

其治暑湿之症，不论偏寒、偏热，都可应用，临床经常与佩兰配伍同用。

用于外感风寒兼有湿阻中焦的症候，常配伍紫苏、陈皮等同用。

此外，可治鼻渊，常配猪胆汁等同用。

紫苏叶，性味：辛，微温，无毒，主治脾胃气滞，胸闷，呕吐之证。

本品具行气宽中，和胃止呕功效。

偏寒者，每与广藿香同用；偏热者，可与黄连同用。

偏气滞痰结者，常与半夏、厚朴同用。

凡气滞湿阻，胃气不和，脘腹胀闷，呕恶崖.漫者，可与广藿香、陈皮、半夏曲、茯苓等配伍，以行气化湿和中。

主治外感风寒，恶寒发热，头痛无汗，咳嗽气喘，脘腹胀闷，呕恶腹泻，咽中梗阻，妊娠恶阻，胎动不安，食鱼蟹中毒，痈疮蛇毒辣。

白术，白术味苦、甘，性温；归脾、胃经；芳香质柔，可升可降，守而不走具有健脾益气，燥湿利水，固表止汗，安胎的功效，主治脾气虚弱，食少腹胀，大便溏泻；痰饮，水肿，小便不利，湿痹酸痛，气虚自汗，胎动不安。

利水消肿、固表止汗、除湿治痹宜生用；健脾和胃宜炒用；健脾止泻宜炒焦用。

脾气不足，形痩面黄，不思饮食，脘腹胀满，大便溏薄者，可与人参、茯苓、炙甘草等配伍，以增健脾益气之功。

过去有报道白术对胃肠道功能（如胃酸的胃液分泌，推进性肠蠕动等）无影响，亦无抗溃疡、抗炎和镇痛作用，不影响正常体温，对中枢神经系统无明显抑制作用，后者被认为可以作为与苍术相区别的依据。

近报道，白术对家兔离体小肠自发活动的影响多不相同，白术能增强兔离体小肠自发性收缩活动，使其收缩幅度加大，白术油抑制肠管的自发运动，或白术对家兔离体小肠的自发运动影响不明显。

白术提取物50mg和200mg/kg灌胃给药，对动物水浸束缚应激性溃疡，有显著抑制效果。

大腹皮，味辛；性微温。

归脾、胃、大肠、小肠经。

主治胃肠气滞，脘腹胀闷，大便不爽。

该品辛能行散，主入脾胃经，能行气导滞，为宽中利气之捷药。

治食积气滞之脘腹痞胀，嗳气吞酸、大便秘结或泻而不爽，可与枳实等同用；若治湿阻气滞之脘腹胀满，可与广藿香、川芎、厚朴等同用。

古籍《日华子本草》：下一切气，止霍乱，通大小肠，健脾开胃，调中。

《开宝本草》：主冷热气攻心腹，大肠壅毒，痰膈，醋心。

并以姜盐同煎，入疏气药良。

《纲目》：降逆气，消肌肤中水气浮肿，脚气壅逆，瘴疟痞满，胎气恶阻胀闷。

《本草再新》：泻肺，和胃气，利湿追风，宽肠消肿，理腰脚气，治疟疾泻痢。

甘葛，性味甘、辛、凉，为解表药，主治外感发热、头项强痛、麻疹初起、疹出不畅、温病口渴、消渴、泄泻、痢疾、高血压、冠心病。

苍术，一般根状茎入药，为运脾药，性味苦温辛烈，有燥湿、化浊、止痛之效。

苍术具有燥湿健脾，祛风湿的功效。

主治湿阻中焦，风寒湿痹，脚膝肿痛，痿软无力，雀目夜盲。

《珍珠囊》日："能健胃安脾，诸湿肿非此不能除。

"《本草纲目》曰："治湿痰留饮……及脾湿下流，浊沥带下，滑泻肠风。

"《新修本草》称其能"利小便"调整胃肠运动功能，苍术煎剂、苍术醇提物在一定剂量范围内能明显缓解乙酰胆碱所致家兔离体小肠痉挛，而对肾上腺素所致小肠运动抑制，则有一定的对抗作用。

抗溃疡：苍术有较强的抗溃疡作用。

实验发现，茅苍术及北苍术对幽门结扎型溃疡、幽门结扎-阿司匹林溃疡、应激性溃疡有较强的抑制作用，两种苍术均能显著抑制溃疡、动物的胃液量、总酸度、总消化能力及胃黏膜损害。

白蒺藜，可以平肝解郁，祛风明目。

用于肝阳眩暈头痛，肝郁胁痛，风热头痛，目赤肿痛，皮肤瘙痒等症。

豆蔻为多年生常绿草本植物，产岭南。

高丈许，外形像芭蕉，叶大，披针形，花淡黄色，秋季结实，果实扁球形，种子像石榴子，可入药，有香味。

可用于化湿消痞，行气温中，开胃消食。

用于湿浊中阻，不思饮食，湿温初起，胸闷不饥，寒湿呕逆，胸腹胀痛，食积不消。

枳实，味苦；辛；寒。

归脾、胃、肝、心经。

功效积滞内停；痞满胀痛；大便秘结；泻痢后重；结胸；胃下垂；子宫脱垂；脱肛。

枳实对胃肠的作用：枳实、枳壳的水煎剂、酊剂及流浸膏对小鼠、家兔的离体肠管及家兔的在体肠管均有抑制作用，水煎液使胃、肠瘘狗的胃肠收缩节律有力，呈兴奋作用，但抑制狗在体胃肠运动.枳实提取物对乙酰胆碱和组胺所致肠管收缩有明显的拮抗作用。

香附可以理气解郁，调经止痛；安胎。

主胁肋胀痛；乳房胀育；疝气疼痛；月经不调；脘腹痞满疼痛；嗳气吞酸，呕恶；经行腹痛；崩漏带下；胎动不安。

用于肝郁气滞，胸、胁、脘腹胀痛，消化不良，胸脘痞闷，寒疝腹痛，乳房胀痛，月经不调，经闭痛经。

香附对胃肠的作用：按常规方法制备家兔离体肠管，用记紋鼓描记香附挥发油对离体肠管的影响。

结果表明，当香附挥发油浓度为 5μg/ml时可抑制肠管的收缩，当浓度增加至20μg/ml时，显明显的抑制作用，使肠管收缩幅度降低、张力下降。

SinghN亦报道，香附醇提取物20μg/ml浓度时，对离体兔回肠平滑肌有直接抑制作用，治气疾心腹胀满，胸膈噎塞，噫气吞酸，胃中痰逆呕吐及宿酒不解，不思饮食。

川芎味辛，性温，归肝、胆、心经，气香升散，具有活血行气，祛风止痛的功效，主治月经不调，痛经，经闭，难产，胞衣不下，产后恶露腹痛，肿块，心胸胁疼痛，跌打损伤肿痛，头痛眩晕目暗，风寒湿痹，肢体麻木，痈疽疮疡。

橘皮，味辛而微苦，温，入脾、肺经。

有理气调中，燥湿化痰功效，可用于治疗脾胃气滞，脘腹胀满，呕吐，或湿浊中阻所致胸闷、纳呆、便溏，但阴津亏损，内有实热者慎用，用于脾虚饮食减少、消化不良，以及恶心呕吐等症。

该品燥湿而能健脾开胃，适用于脾胃虚弱、饮食减少、消化不良、大便泄泻等症，常与白术、茯苓等配合应用。

因其既能健脾，又能理气，故往往用作补气药之佐使，可使补而不滞，有防止壅遏作胀作用。

虎杖，微苦，微寒。

归肝、胆、肺经，根状茎供药用，有活血、散瘀、通经、镇咳等功效，可以清热解毒，利胆退黄，祛风利湿，散瘀定痛，止咳化痰。

用于关节痹痛，湿热黄疸，经闭，产后瘀血不下，癥瘕，咳嗽痰多，水火烫伤，跌打损伤，痈肿疮毒。

元胡，为罂粟科植物，以块茎入药，有活血散瘀，理气止痛的作用，主治胃痛、痛经、跌打损伤等，它味辛、苦，性温。

有活血散瘀，利气止痛的功能，用于全身各部气滞血瘀之痛，痛经，经闭，症瘕，产后瘀阻，跌扑损伤，疝气作痛。

薏苡仁，性凉，味甘、淡，为禾本科植物薏苡的种仁。

有健脾渗湿，除痹止泻。

用于水肿、脚气、小便不利、湿痹拘挛、脾虚泄泻的功效。

功能主治：健脾渗湿，除痹止泻。

用于水肿、脚气、小便不利、湿痹拘挛、脾虚泄泻。

黄苓，黄苓别名山茶根、土金茶根。

为唇形科植物，以根入药。

有清热燥湿，凉血安胎，解毒功效。

主治温热病、上呼吸道感染、肺热咳嗽、湿热黄胆、肺炎、痢疾、咳血、目赤、胎动不安、高血压、痈肿疖疮等症。

黄芩的临床应用抗菌比黄连还好，而且不产生抗药性。

大血藤，味苦，平。

归大肠、肝经。

功能主治：清热解毒，活血，祛风。

用于肠痈腹痛，经闭痛经，风湿痹痛，跌扑肿痛。

具有败毒消痈，活血通络，祛风杀虫的作用。

治急、慢性阑尾炎，风湿痹痛，赤痢，血淋，月经不调，疳积，虫痛，跌扑损伤等症。

白芨，性寒、味苦、甘、涩，无毒；归肺、胃、肝经。

具有收敛止血，消肿生肌的功能。

主治肺痨略血，吐血，衄血，便血，外伤出血，痈疮肿毒，瘰疬，痔漏，烧烫伤，手足皲裂，肛裂等病症。

与本发明其他中药配伍，治疗肠炎效果明显。

小米，是粟（Setariaitalica)脱壳制成的粮食，因其粒小，直径1毫米左右，故名。

原产于中国北方黄河流域，中国古代的主要粮食作物，所以夏代和商代属于"粟文化"。

粟生长耐旱，品种繁多，俗称"粟有五彩"，小米性凉味甘，可以止呕消嗳，养肠胃，通便，止泄，补血益气，健脾，降糖消渴，养阴补虚，对胃肠道有很好的调理和滋补作用：主治消化不良：B族维生素可促进消化液分泌，维持和促进肠道蠕动，有利于排便。

及口角生疮的功效，并且养胃：中和胃酸，缓解胃痛。

小米具有防止泛胃、呕吐的功效。

从我国传统中医角度讲，慢性肠炎的病因病机，有饮食不节，戕伤中州，或外邪内侵，损及脾胃，或忧患郁怒，肝失疏泄，横逆犯胃，以及禀赋不足，脾胃虚弱等情形，其病表在"肠"，但与"胃"、"脾"、"肝"、"肾"却关系密切，病机特点是虚中夹实，因此通过本发明上述中药配伍以及制备方法获得的组合物，采用辩证的方法有效的达到调理肠道与五脏六腑的功效，无毒副作用，效果稳定，与西药相比达到事半功倍的疗效。

临床实验1: 1)、观察时间：在本发明技术方案未曾披露的情况下，选择2012年3月到2012年8月的6个月时间。

2)、观察对象：在广东省深圳市中医院消化科选择10例慢性肠炎病例：男6例，女4例；年龄：40—55岁5例，60—75岁5例；职业：普通上班族5例，退休人员5例。

病症：反复发作的腹痛、腹胀、腹泻、泻下粘液或脓血便，发作期大便3次/日以上，伴排便不畅或里急后重；舌苔多黄腻或白腻；全部病便均经纤维结肠镜检査确诊。

3)、使用方法：将本发明制剂口服液在餐后半小时服用，每日3 次，每次200ml，2个月为1疗程，3个疗程作为疗效观察。

4)、观察效果：在连续服用3个疗程后，临床症状、体征消失，纤维结肠镜复查正常，肠黏膜病变恢复正常的6例，临床症状明显减轻，体征基本消失，纤维结肠镜复查好转，肠黏膜病变明显改善的2例，治疗前后临床症状和体征无改善，纤维结肠镜复査无好转的2例，总有效率80%。

临床实验2: 1)、观察时间：在本发明技术方案未曾披露的情况下，选择2013年1月到2013年6月的6个月时间。

2)、观察对象：在广东省深圳市福田区中医院消化科选择20例病例：男12例，女8例；年龄：32—55岁10例，56—75岁10例；职业：曾担任领导岗位公务员10例，普通教师10例。

病症：反复发作的腹痛、腹胀、腹泻、泻下粘液或脓血便，发作期大便3次/日以上，伴排便不畅或里急后重；舌苔多黄腻或白腻；全部病便均经纤维结肠镜检査确诊。

3)、使用方法：将本发明制剂口服液在餐后半小时服用，每日3次，每次200ml，2个月为1疗程，3个疗程作为疗效观察。

4)、观察效果：在连续服用3个疗程后，临床症状、体征消失，纤维结肠镜复查正常，肠黏膜病变恢复正常的12例，临床症状明显减轻，体征基本消失，纤维结肠镜复查好转，肠黏膜病变明显改善的3例，治疗前后临床症状和体征无改善，纤维结肠镜复查无好转的5例，总有效率 75%。

临床实验3: 1)、观察时间：在本发明技术方案未曾披露的情况下，选择2013年9月到2014年2月的6个月时间。

2)、观察对象：在广东省深圳市松岗人民医院消化科选择30例病例：男12例，女18例；年龄：35—55岁16例，60—75岁14例；职业：普通民营企业主14例，普通退休教师16例。

病症：反复发作的腹痛、腹胀、腹泻、泻下粘液或脓血便，发作期大便3次/日以上，伴排便不畅或里急后重；舌苔多黄腻或白腻；全部病便均经纤维结肠镜检査确诊。

3)、使用方法：将本发明制剂口服液在餐后半小时服用，每日3次，每次200ml，2个月为1疗程，3个疗程作为疗效观察。

4)、观察效果：在连续服用3个疗程后，临床症状、体征消失，纤维结肠镜复査正常，肠黏膜病变恢复正常的18例，临床症状明显减轻，体征基本消失，纤维结肠镜复査好转，肠黏膜病变明显改善的6例，治疗前后临床症状和体征无改善，纤维结肠镜复查无好转的6例，总有效率80%。

结合以上临床数据及本发明的理论依据，可见本发明有益效果在于，本发明制成的制剂，对于治疗慢性肠炎具有良好效果，而且无毒，无副作用，效果稳定，制取工艺简便易行。

具体实肺式下面结合实施例对本发明详细加以说明：实施例1：本发明制剂是由广藿香、紫苏叶、白术、大腹皮、甘葛、苍术、白蒺藜、豆蔻、枳实、香附、川芎、橘皮、虎杖、元胡、薏苡仁、黄芩、大血藤、白芨和小米制备成的组合物制剂，其中各组分的质量配比为：广藿香12g紫苏叶10g白术10g大腹皮12g甘葛12g苍术15g白蒺藜10g豆蔻12g枳实8g香附15g川芎15g橘皮13g虎杖12g元胡8g薏苡仁10g黄芩12g大血藤13g白芨10g小米16g。

上述治疗慢性肠炎中药的制备方法，包括如下步骤： 1)、将紫苏叶放入小锅进行小炒至表面微焦，然后经粉碎机粉碎并过80目筛，备用； 2)、将广藿香、白术、大腹皮、甘葛、白蒺藜、豆蔻、枳实、小米、黄芩、大血藤按比例配好，经过粉碎机粉碎成粉末并过90目筛，自然晾干，备用； 3)、将步骤1)和2)中的各组分粉末混合在一起，加入纯净水煎煮两次，第一次加入8倍纯净水小火煎煮1小时，第二次加入4倍纯净水小火煎煮半小时，然后合并煎液并过滤，备用； 4)、将剩下的苍术、香附、川芎、橘皮、虎杖、元胡、薏苡仁、白芨按比例配好，经过粉碎机粉碎成粉末并过80目筛，自然晾干，备用； 5)、将歩骤4)中各组分粉末混合在一起，加入4〜6倍70%〜80%的乙醇，加热回流3〜5个小时，提取过滤获得滤液；然后在剩下的药渣中再次加入2〜4倍65%〜75%的乙醇，加热回流2〜3个小时，提取过滤获得滤液;将两次获得的滤液合并在一起，减压浓缩除去乙醇溶剂，干燥，获得干膏； 6)、将上述歩骤5)中获得的干膏进行超微粉碎成粉末并过200目筛，然后将粉末加入歩骤3)中的合并煎液，混合摇勾即可制得。

制取的上述中药组合物溶液制剂可以用于口服，如果能够早中晚各饮用一次并长期饮用，效果更好。

雄例2: 本发明还可优选的原料质量为（克）：广藿香12g紫苏叶10g白术10g大腹皮12g甘葛12g苍术15g白蒺藜10g豆蔻12g枳实8g香附15g川芎10g橘皮13g虎杖12g元胡8g薏苡仁10g黄芩12g大血藤13g白茇10g 制备方法如实施例1。

实施例3: 本发明还可优选的原料质量为（克）：广藿香15g紫苏叶12g白术9g大腹皮15g甘葛10g苍术12g白蒺藜12g豆蔻10g枳实8g香附12g川芎14g橘皮12g虎杖8g元胡8g薏苡仁12g黄芩10g大血藤8g白芨10g小米15g。

制备方法如实施例1。

鍾例4: 本发明还可优选的原料质量为（克）：广藿香18g紫苏叶15g白术12g大腹皮16g甘葛12g苍术15g白蒺藜13g豆¾15g枳实12g香附16g川芎g橘皮16g虎杖10g元胡12g薏苡仁15g黄苳16g大血藤13g白芨12g小米18g。

制备方法如实施例1< 实施例5: 本发明还可优选的原料质量为（克）：广藿香16g紫苏叶18g白术15g大腹皮14g甘葛15g苍术18g白蒺藜15g豆蔻18g枳实14g香附18g川芎16g橘皮14g虎杖12g元胡13g薏苡ί:二13；黄芩18g大血藤15g白芨15g小米18g。

制备方法如实施例1。

实施例6: 本发明还可优选的原料质量为〔克）：广藿香15g紫苏叶18g白术15g大腹皮16g甘葛15g苍术20g白蒺藜12g豆蔻20g枳实16g香附16g川芎18g橘皮15g虎杖15g元胡15g薏苡:二12黄芩16g大血藤16g白芨13g小米20g。

制备方法如实施例1。

上述实施例仅是本发明众多实施方式的几种，如将各配方按技术方案影响，也将落在本发明的权利保护范围之内。

Claims 权利要求 1、一种治疗慢性肠炎的中药，其特征在于，本发明制剂是由广藿香、紫苏叶、白术、大腹皮、甘葛、苍术、白蒺藜、豆蔻、枳实、香附、川芎、橘皮、虎杖、元胡、薏苡仁、黄芩、大血藤、白笈和小米制备成的组合物制剂，其中各组分的质量配比为：广藿香12-20g紫苏叶10-22g8-18g大腹皮10—18g甘葛8-15g苍术 10-20g 白蒺藜8-16g豆蔻12-20g枳实8-16g香附10-18g川芎10-18g橘皮 10-18g 虎杖8-15g元胡6-15g薏苡仁 8-15g 黄芩10-18g大血藤8-16g白芨8-15g小米10-20g。

2、根据权利要求1所述的治疗慢性肠炎的中药，其特征还在于，其中各组分的质量配比为：广藿香12-18g紫苏叶10-18g白术 8-12g 大腹皮12-18g甘葛8-12g苍术10-15g 白蒺藜8-12g豆蔻12-16g枳实 8-12g 香附10-15g川芎10-14g橘皮 10-15g 虎杖8-12g元胡6-10g薏苡仁 8-12g 黄芩10-15g大血藤8-12g白 8-12g 小米12-18g。

3、根据权利要求1或2所述的治疗慢性肠炎的中药，其特征还在于，其中各组分的质量配比为：广藿香15g紫苏叶12g白术9g大腹皮15g甘葛10g苍术12g白蒺藜12g豆蔻10g枳实8g香附12g川芎14g橘皮12g虎杖8g元胡8g薏苡仁12g黄芩10g大血藤8g白芨10g小米15g。

4、一种治疗慢性肠炎的中药的制备方法，其特征在于，其包括如下步骤： 1)、将紫苏叶放入小锅进行小炒至表面微焦，然后经粉碎机粉碎并过80目筛，备用； 2)、将广藿香、白术、大腹皮、甘葛、白蒺藜、豆蔻、枳实、小米、黄芩、大血藤按比例配好，经过粉碎机粉碎成粉末并过90目筛，自然晾干，备用； 3)、将歩骤1)和2)中的各组分粉末混合在一起，加入纯净水煎煮两次，第一次加入10倍纯净水小火煎煮1小时，提取滤液备用，第二次加入6倍纯净水小火煎煮半小时，然后合并煎液并过滤，备用； 4)、将剩下的苍术、香附、川芎、橘皮、虎杖、元胡、薏苡仁、白芨按比例配好，经过粉碎机粉碎成粉末并过80目筛，自然晾干，备用； 5)、将步骤4)中各组分粉末混合在一起，加入4〜6倍70%〜80%的乙醇，加热回流3〜5个小时，提取过滤获得滤液；然后在剩下的药渣中再次加入2〜4倍65%〜75%的乙醇，加热回流2〜3个小时，提取过滤获得滤液；将两次获得的滤液合并在一起，减压浓缩除去乙醇溶剂，干燥，获得干膏； 6)、将上述歩骤5)中获得的干膏进行超微粉碎成粉末并过200目筛，然后将粉末加入步骤3)中的合并煎液，混合摇匀即可制得。

制取的上述中药组合物溶液制剂可以用于口服，如果能够早中晚各适量饮用一次并长期饮用，效果更好。

PCT/CN2014/075336 2014-03-31 2014-04-15 一种治疗慢性肠炎的中药及其制备方法 WO2015149389A1 (zh) PriorityApplications(2) ApplicationNumber PriorityDate FilingDate Title CN201410124715.8A CN103861015A (zh) 2014-03-31 2014-03-31 一种治疗慢性肠炎的中药及其制备方法 CN201410124715.8 2014-03-31 Publications(1) PublicationNumber PublicationDate WO2015149389A1 true WO2015149389A1 (zh) 2015-10-08 Family ID=50900403 FamilyApplications(1) ApplicationNumber Title PriorityDate FilingDate PCT/CN2014/075336 WO2015149389A1 (zh) 2014-03-31 2014-04-15 一种治疗慢性肠炎的中药及其制备方法 CountryStatus(2) Country Link CN (1) CN103861015A (zh) WO (1) WO2015149389A1 (zh) Citations(4) *Citedbyexaminer,†Citedbythirdparty Publicationnumber Prioritydate Publicationdate Assignee Title CN1142367A (zh) * 1995-08-08 1997-02-12 蔡灵芝一种治疗肠粘连、肠梗阻的药物 CN1840050A (zh) * 2003-12-23 2006-10-04 江苏康缘药业股份有限公司一种加味藿香软胶囊的质量控制方法 CN101785835A (zh) * 2010-02-28 2010-07-28 泰一和浦（北京）中医药研究院有限公司一种治疗慢性肠炎的中药组合物及其制备方法 CN103877483A (zh) * 2014-03-31 2014-06-25 袁志贤一种治疗慢性胃炎的中药及其制备方法 FamilyCitesFamilies(3) *Citedbyexaminer,†Citedbythirdparty Publicationnumber Prioritydate Publicationdate Assignee Title CN1136902C (zh) * 2001-08-21 2004-02-04 广东庆发药业有限公司化湿消滞片及其制备方法 JP2006182679A (ja) * 2004-12-27 2006-07-13 DaichoKikaku:Kk ストレス性胃炎予防・治療剤 CN102772701A (zh) * 2012-06-14 2012-11-14 司明清一种治疗浅表性胃炎的中药口服液 2014 2014-03-31 CN CN201410124715.8A patent/CN103861015A/zh active Pending 2014-04-15 WO PCT/CN2014/075336 patent/WO2015149389A1/zh active ApplicationFiling PatentCitations(4) *Citedbyexaminer,†Citedbythirdparty Publicationnumber Prioritydate Publicationdate Assignee Title CN1142367A (zh) * 1995-08-08 1997-02-12 蔡灵芝一种治疗肠粘连、肠梗阻的药物 CN1840050A (zh) * 2003-12-23 2006-10-04 江苏康缘药业股份有限公司一种加味藿香软胶囊的质量控制方法 CN101785835A (zh) * 2010-02-28 2010-07-28 泰一和浦（北京）中医药研究院有限公司一种治疗慢性肠炎的中药组合物及其制备方法 CN103877483A (zh) * 2014-03-31 2014-06-25 袁志贤一种治疗慢性胃炎的中药及其制备方法 Non-PatentCitations(1) *Citedbyexaminer,†Citedbythirdparty Title WANG,YONGFENG:"biànzhèngzhìliáomànxìngchángyánjingyàn",HEBEIJOURNALOFTRADITIONALCHINESEMEDICINE,vol.35,no.7,31July2013(2013-07-31),pages1007 * AlsoPublishedAs Publicationnumber Publicationdate CN103861015A (zh) 2014-06-18 SimilarDocuments Publication PublicationDate Title KR101787432B1 (ko) 2017-10-18 녹용발효물과효모가수분해물을함유한생리불순및생리통개선한약조성물제조방법 CN104288701A (zh) 2015-01-21 一种治疗胆囊炎的中药组合物 CN103751579B (zh) 2016-06-29 治疗鼻咽癌放疗引起口腔粘膜炎的药物组合物及其制备方法 CN104383288A (zh) 2015-03-04 一种用于治疗牛肺炎的药物组合物及其制备方法 WO2015149394A1 (zh) 2015-10-08 一种治疗慢性胃炎的中药口服液 CN104042971A (zh) 2014-09-17 用于治疗阴虚毒热型肺癌的药物组合物及其制备方法 WO2015149393A1 (zh) 2015-10-08 一种治疗慢性胃炎的中药及其制备方法 CN105435197A (zh) 2016-03-30 一种治疗桥本氏病的药物组合物及其制备方法 CN104001045A (zh) 2014-08-27 一种用于治疗犬肺炎的药物及其制备方法 CN103230486B (zh) 2014-11-05 一种中药组合物及其制备方法以及在制备治疗脂肪肝药物中的应用 CN105435190A (zh) 2016-03-30 用于治疗寒热错杂型哮病的中药组合物及其制备方法 CN104998197A (zh) 2015-10-28 一种用于治疗肝癌的中药组合物 WO2015149390A1 (zh) 2015-10-08 一种治疗慢性肠炎的中药口服液及其制备方法 CN104984141A (zh) 2015-10-21 一种治疗便秘的方剂及其制备方法 CN104474430A (zh) 2015-04-01 一种治疗肝肾阴虚型霉菌性阴道炎的中药及制备方法 WO2015149391A1 (zh) 2015-10-08 一种治疗慢性肠炎的中药制剂及其制备方法 KR101555937B1 (ko) 2015-09-25 조기성숙지연을위한한약추출물농축액및그제조방법 WO2015149389A1 (zh) 2015-10-08 一种治疗慢性肠炎的中药及其制备方法 CN105920238A (zh) 2016-09-07 一种治疗气滞血瘀型盆腔炎的药物及其制备方法 CN105166546A (zh) 2015-12-23 一种奶牛配合饲料及其制备方法 CN105560693A (zh) 2016-05-11 治疗痔疮的药物组合物 CN104825977A (zh) 2015-08-12 一种治疗脾虚伤食型产后伤食的中药组合物及制备方法 CN105031332A (zh) 2015-11-11 一种治疗痰湿内阻型乳汁不通的中药组合物 CN103933427A (zh) 2014-07-23 用于治疗结节性霉素疹的药物组合物及其制备方法 CN104873693A (zh) 2015-09-02 一种用于止嗽的中药制剂、制备方法及应用 LegalEvents Date Code Title Description 2015-11-18 121 Ep:theepohasbeeninformedbywipothatepwasdesignatedinthisapplication Refdocumentnumber: 14887809 Countryofrefdocument: EP Kindcodeofrefdocument: A1 2016-09-30 NENP Non-entryintothenationalphasein: Refcountrycode: DE 2017-08-02 32PN Ep:publicnotificationintheepbulletinasaddressoftheadresseecannotbeestablished Freeformattext: NOTINGOFLOSSOFRIGHTSPURSUANTTORULE112(1)EPC(EPOFORM1205ADATED21/03/2017) 2017-12-20 122 Ep:pctapplicationnon-entryineuropeanphase Refdocumentnumber: 14887809 Countryofrefdocument: EP Kindcodeofrefdocument: A1

請為這篇文章評分？

延伸文章資訊

傳統醫學科認識中藥—黃柏- 臺中 - 台中榮總

(1)治療消化道感染：對急、慢性細菌性痢疾，或急性腸炎，證屬濕熱者，使用黃柏及其製劑，可獲得改善。 (2)外用局部感染及體表、皮膚疾病。注意事項：.

慢性腸炎中藥方劑 - 壹讀

慢性腸炎對於我們來說，它是一種很常見的疾病，但很多人都對慢性腸炎症狀不是太了解。那麼有哪些中藥方劑學來治療慢性腸炎呢?又有哪些慢性腸炎的治療 ...

慢性腸炎用中藥調理效果好，這有幾個秘方

腸炎常用的中藥方 - 三度漢語網

直腸炎的治療方法是非常多的，那麼在中藥當中我們可以選擇太子參、灸黃芪、白朮、甘草、罌慄殼和白芍，以及石榴皮和明礬，這位藥劑主要是適合那些慢性的查直腸炎患者，由於 ...

肠炎 - 中药方大全

方 | 汤 | 丸 | 法 | 性 | 三 | 治疗 | 疮 | 有 | 中药. 肠炎. 胃肠炎奇效方 · 肠炎汤2号 · 肠炎汤1号 ...

一种治疗慢性肠炎的中药及其制备方法 - Google

文章推薦指數： 80 %

請為這篇文章評分？

延伸文章資訊

最新文章

相關網站資訊

月子中心

剖腹產

下訂單英文書信

著迷

憂鬱症發作怎麼辦

心悸症狀

重度憂鬱症

一种治疗慢性肠炎的中药及其制备方法 - Google

文章推薦指數： 80 %

請為這篇文章評分？

延伸文章資訊

最新文章

相關網站資訊

月子中心

剖腹產

下訂單 英文 書信

著迷

憂鬱症發作怎麼辦

心悸症狀

重度憂鬱症

下訂單英文書信