How is dosage compensation accomplished in humans

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Dosage compensation and gene expression on the mammalian X ...In mammals this is accomplished by two processes—X chromosome inactivation that silences most genes on one X chromosome in females, leading to functional X ... tw | twDosage Compensation in Drosophila - NCBIThe first evidence that dosage compensation in Drosophila is achieved by regulating ... and both human and fly MSL2 show ubiquitin ligase activity directed ...THE PHENOMENON OF... · REGULATORS OF DOSAGE... · CHROMATIN...Large-Scale Population Study of Human Cell Lines Indicates that ...2008年1月18日 · Dosage compensation in humans involves X chromosome inactivation, ... We have carried out a large-scale analysis of gene expression in ... | Dosage compensation and sex-specific epigenetic landscape of the ...2017年6月15日 · pisum genome to autosomes and X chromosome has recently been performed [38]. We thus reanalyzed previously published A. pisum RNA-seq data from ... tw | twDosage compensation in male flies: Balance between sexes2012年7月19日 · In humans, for example, women have two X chromosomes, whereas men have only ... This is done by means of the dosage compensation complex, ... twMammalian X chromosome inactivation evolved as a dosage ...2012年4月3日 · Here we focused on protein-complex genes in humans to test for the evolution of dosage compensation in dosage-sensitive X-linked genes. We used ...Evolution of Sex Chromosome Dosage Compensation in Animals2017年8月23日 · For species with well-differentiated sex chromosomes, this can be readily accomplished by examining differences in DNA abundance between males ...X-chromosome-wide profiling of MSL-1 distribution and dosage ...2006年3月17日 · Abstract. In Drosophila, dosage compensation is achieved by a twofold up-regulation of the male X-linked genes and requires the association ...Distinct mechanisms mediate X chromosome dosage compensation ...2021年7月15日 · Three distinct molecular strategies to achieve DC have been previously described in nematodes, fruit flies, and mammals. Is this a consequence ...RNA sequencing reveals a complete but an unconventional type of ...2017年7月12日 · Sex chromosomal dose difference between sexes is often normalized by a gene regulatory mechanism called dosage compensation (DC).