Bio-optimized Curcuma longa extract is efficient on knee ...
文章推薦指數： 80 %
Two recent meta-analyses evaluating a large number of dietary supplements ranked curcumin as one of the most effective compounds for pain ... Skiptomaincontent Advertisement SearchallBMCarticles Search DownloadPDF Researcharticle OpenAccess Published:27July2019 Bio-optimizedCurcumalongaextractisefficientonkneeosteoarthritispain:adouble-blindmulticenterrandomizedplacebocontrolledthree-armstudy Y.Henrotin ORCID:orcid.org/0000-0002-2846-43981,2,3,M.Malaise4,R.Wittoek5,K.deVlam6,J.-P.Brasseur7,F.P.Luyten8,Q.Jiangang9,M.VandenBerghe10,R.Uhoda11,J.Bentin12,T.DeVroey13,L.Erpicum14,A.F.Donneau15&Y.Dierckxsens16 ArthritisResearch&Therapy volume 21,Article number: 179(2019) Citethisarticle 8347Accesses 26Citations 6Altmetric Metricsdetails ALettertothisarticlewaspublishedon11February2020 AbstractObjectivesComparisonoftwodosesofbio-optimizedCurcumalongaextract(BCL)inthemanagementofsymptomatickneeosteoarthritis(OA).MethodsAprospective,randomized,3-month,double-blind,multicenter,three-group,placebo-controlledtrialassessingPatientGlobalAssessmentofDiseaseActivity(PGADA)andserumsColl2-1,abiomarkerofcartilagedegradation,asco-primaryendpoints.Painonvisualanalogscale(VAS),KneeinjuryandOsteoarthritisOutcomeScore(KOOS),andparacetamol/non-steroidalanti-inflammatorydrug(NSAID)consumptionwereusedassecondaryendpoints.ResultsOnehundredfiftypatientswithkneeOAwerefollowedfor90 days.LowandhighdosesofBCLshowedagreaterdecreaseofPGADAthanplacebo.AnalysisofsColl2-1showedintheplaceboandBCLlow-dosegroups,butnotintheBCLhigh-dosegroup,atransientbutnon-significantincreaseofsColl2-1betweenT0andT1.Thereafter,inallgroups,sColl2-1decreasedbetweenT1andT3(allp 80%inallgroupsandcomparableintheplaceboandBCLgroups,demonstratingexcellentcompliance.ThiswasconfirmedbycurcuminmeasurementinPP.CurcuminserumlevelsdramaticallyincreasedatT1(p
延伸文章資訊
- 1EFFICIENT在劍橋英語詞典中的解釋及翻譯
We need someone really efficient who can organize the office and make it run smoothly. Thesaurus:...
- 2Efficient Definition & Meaning - Merriam-Webster
Efficient most often describes what is capable of producing desired results without wasting mater...
- 3What is Efficient Learning | IGI Global
What is Efficient Learning? Definition of Efficient Learning: Using a minimum of resources to ach...
- 4I was efficient | English examples in context | Ludwig
Among the seed extracts, it was found that AMS-I was efficient in quenching the hydroxyl radical ...
- 5he was efficient in his work 中文 - 查查綫上辭典
he was efficient in his work中文:他工作效率高…，點擊查查權威綫上辭典詳細解釋he was efficient in his work的中文翻譯，he was eff...
