麥芽糖酶-葡糖澱粉酶- 維基百科，自由的百科全書

麥芽糖酶-葡糖澱粉酶是α-葡糖苷酶消化酶。

它由兩個具有不同底物特異性的亞基組成。

重組酶研究表明，其N-末端催化結構域對麥芽糖具有最高活性，而C-末端結構域具有更廣泛的 ... 麥芽糖酶-葡糖澱粉酶 位於7號人類染色體的基因 語言 監視 編輯 麥芽糖酶-葡糖澱粉酶（英語：Maltase-glucoamylase）是一種由人體MGAM基因編碼的酶。

[6][7]麥芽糖酶-葡糖澱粉酶已知的結構PDB直系同源搜索:PDBeRCSBPDBID列表2QLY、​2QMJ、​3CTT、​3L4T、​3L4U、​3L4V、​3L4W、​3L4X、​3L4Y、​3L4Z、​3TON、​3TOP識別號別名MGAM；,MG,MGA,Maltase-glucoamylase外部IDOMIM：154360MGI：1203495HomoloGene：130099GeneCards：MGAM為以下藥物的標靶米格列醇[1]基因位置（人類）染色體7號染色體[2]基因座7q34起始141,907,813bp[2]終止142,106,747bp[2]基因位置（小鼠）染色體小鼠6號染色體[3]基因座6|6B1起始40,605,765bp[3]終止40,746,057bp[3]基因本體分子功能•hydrolaseactivity,actingonglycosylbonds•maltosealpha-glucosidaseactivity•hydrolaseactivity,hydrolyzingO-glycosylcompounds•催化活性•alpha-1,4-glucosidaseactivity•水解酶活性•amylaseactivity•glucan1,4-alpha-glucosidaseactivity•carbohydratebinding•alpha-glucosidaseactivity細胞組分•integralcomponentofmembrane•細胞膜•apicalplasmamembrane•外排體•膜•tertiarygranulemembrane•ficolin-1-richgranulemembrane生物學過程•polysaccharidedigestion•代謝•starchcatabolicprocess•maltosemetabolicprocess•neutrophildegranulation•碳水化合物代謝Sources:Amigo/QuickGO直系同源物種人類小鼠Entrez8972232714EnsemblENSG00000257335​ENSG00000282607ENSMUSG00000068587UniProtO43451無數據mRNA​序列NM_004668​NM_001365693NM_001171003​NM_001368875蛋白序列NP_004659​NP_001352622無數據基因位置​（UCSC）Chr7:141.91–142.11MbChr6:40.61–40.75MbPubMed​查找[4][5]維基數據檢視/編輯人類檢視/編輯小鼠麥芽糖酶-葡糖澱粉酶是α-葡糖苷酶消化酶。

它由兩個具有不同底物特異性的亞基組成。

重組酶研究表明，其N-末端催化結構域對麥芽糖具有最高活性，而C-末端結構域具有更廣泛的底物特異性和對葡萄糖寡聚體的活性。

[8] 在小腸中，這種酶與蔗糖-異麥芽糖酶和α-澱粉酶協同作用，以消化各種澱粉。

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